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14 October 2024 | Story Reuben Maeko | Photo Reuben Maeko
Diabetes Open Day 2024
Dr Deepa Alexander (Senior Lecturer/Head: Clinical Unit Paediatrics and Child Health) and Dietetics student Anri Nel testing blood glucose and recording the blood glucose values of the children with type 1 diabetes.

The University of the Free State (UFS) Department of Nutrition and Dietetics, in collaboration with the Department of Paediatrics and Child Health, recently hosted a successful Diabetes Open Day designed for children and adolescents with type 1 diabetes mellitus.

The open day, which aimed to provide a supportive environment to learn, connect, and have fun, took place on Friday 27 September in the CR de Wet/Bophelong Building on the Bloemfontein Campus. The day welcomed 10 children and 10 caregivers, offering a comprehensive programme tailored to address the unique needs of young individuals living with diabetes. The participants, aged five to thirteen, engaged in a variety of activities that educated them about their condition, but also empowered them to take control of their health in a positive and proactive way.

Angelique Carson-Porter, Lecturer in the Department of Nutrition and Dietetics and one of the organisers, stated, “Healthy eating is a cornerstone of diabetes management. Rather than viewing dietary restrictions as limitations, diabetes-friendly cooking classes encourage individuals to explore a world of new flavours and ingredients.” The department offered cooking workshops that teaches parents how to prepare delicious, low-sugar, and nutrient-rich dishes.

Education combined with fun activities

The Diabetes Open Day aimed to bring together children who face the same daily challenges in managing type 1 diabetes. Education combined with fun activities were used to teach the children to improve and control their blood sugar levels. The final-year Dietetics students provided practical advice on managing blood sugar levels, the importance of a balanced diet, and the role of physical activity in diabetes care.

While education and support were central to the day’s agenda, the organisers ensured that fun was a key component of the experience. The day included various engaging activities, all designed to promote physical well-being and emotional expression. These activities aimed to help children see that managing diabetes does not mean missing out on the joys of childhood.

Additionally, the open day offered a safe space for children to express their emotions and share their experiences with peers who understand their journey. This sense of community is crucial for building resilience and fostering a supportive network that extends beyond the event.

This event provided the final-year Dietetics students at the UFS with teaching and learning opportunities, as they were caring for and educating these children, as well as preparing the correct food for them. The students were also responsible for planning the open day, developing educational material to take home, and creating games to teach them the importance of physical activity in the management of type 1 diabetes.

Managing diabetes

According to Katleho Stemmer, a student who participated in the open day, managing diabetes can be a challenging experience, but it does not mean it has to be boring or burdensome. Health experts and diabetes patients alike, she continues, are finding innovative ways to transform their routines and make diabetes management a more engaging and enjoyable process. From interactive cooking classes to fitness challenges and support groups, there are countless ways to turn diabetes management into a fun and motivating journey.

“The key to successfully managing diabetes lies in consistency and a positive mindset. By incorporating fun activities, engaging communities, and a creative approach, individuals can transform their diabetes management routines into an enjoyable and sustainable lifestyle.

“Diabetes doesn’t have to define one's life – it can be an opportunity to explore new hobbies, make new friends, and adopt a healthier, more balanced way of living. With the right support and a little bit of fun, managing diabetes can become less of a challenge and more of an empowering adventure. These gatherings help foster a sense of community and mutual support,” she says.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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