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17 October 2024 | Story André Damons | Photo Supplied
Dr Mutshidzi Mulondo
Dr Mutshidzi Mulondo, academic in the Division of Public Health within the Faculty of Health Sciences at UFS.

Dr Mutshidzi Mulondo, an academic in the Division of Public Health within the Faculty of Health Sciences, at the University of the Free State (UFS), has won a prestigious Global Health Award at the margins of the Global Health Summit in London, the UK.

Dr Mulondo, who is a Novartis Reimagining Healthcare Scholar and a Visiting Scholar at the Beaver College of Health Sciences at Appalachian State University, in the US, was a finalist in two categories: ‘Mental Health and Well-being’ and ‘Rising Star’. She won the Zenith Global Health Award under the category ‘Mental Health and Well-being’. The awards ceremony took place on 28 September and saw health professionals and academics gather in Europe for the auspicious occasion.

“This nomination and selection are an honour that bears testament to my dedication and commitment to SDG 3 (Good Health and Well-being). I hope this win serves as inspiration to young people, particularly to young women in academia and in the sciences,” says Dr Mulondo. The awards are an esteemed platform renowned for celebrating global recognition and excellence, fostering collaboration and innovation in the healthcare sector. They further serve as recognition for contributions made through education, research and/or technology and innovation.

Eco-anxiety

Dr Mulondo, who was invited to attend the summit for the first time, joined a panel of speakers on the session theme ‘mental health and climate change’ where she shared insights on eco-anxiety – the intersection of climate change and mental health which was coined by Albrecht as the chronic fear of environmental change.

Research by the McKinsey Health Institute, says Dr Mulondo, a fellow of the UFS Emerging Scholar Accelerator Programme (ESAP) and member of the UNESCO AG for Women in Science, indicates that more than 75% of young people are pessimistic about the future due to climate change. Most young people in the activism frontlines experience activist burn-out from consistent campaigning, while others experience eco-gaslighting from those who feel climate change is a non-issue. These negative emotions are further exacerbated by young people’s exposure to social media of constant images and conversations about environmental degradation due to climate change.

Pact for the future

Dr Mulondo flew to London from New York after participating in the 79th United Nations General Assembly’s Summit of the Future and Science Summit, as well as the New York Climate Week. She further provided insights into the adoption of the Pact for the Future which was adopted during the Summit of the Future. “With only 17% of the Sustainable Development Goals (SDGs) targets on track to be achieved by 2030, 18% stagnant and 17% regressed to pre-2015 when the goals were first adopted (SDG Report 2024), Mental Health still remains among 10 global health issues to track according to the World Health Organisation (WHO),” says Dr Mulondo.

“The Summit of the Future, which is regarded as a once-in-a-generation high-level event,” she continues, “was aimed at establishing a new global consensus to safeguard the present and future generations. Current challenges such as health pandemics, political unrest, and climatic changes were factored into discussions to keep apace with the changing world in the adoption of the Pact for the Future”.

Recommendations and mitigation efforts should focus on encouraging those experiencing eco-anxiety to focus on joining collective action efforts (i.e. campaigns to clean ocean and beach environments (etc,) so that they feel they are doing something towards saving the planet. “This will help alleviate the feelings of ‘hopelessness’ which some experience from not knowing what to do about the environmental degradation. Furthermore, intergenerational collaboration is necessary for young people to voice their concerns and innovative ideas on the issue, while the older generation listens and further shares their lived wisdom. Ultimately, collective support (Ubuntu) is what is needed as part of the mitigation efforts,” concludes Dr Mulondo.

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Dr Charlotte Boucher and Lindi Heyns examine possible anti-microbial activity in the skin of Western olive toad species
2014-12-22

 

Researchers Lindi Heyns and Dr Charlotte Boucher are working together on an interdisciplinary project between the Departments of Zoology and Entomology and Veterinary Biotechnology at the University of the Free State (UFS). The focus of their research is on the preliminary biochemical description of skin secretions in some South African toads.

The project forms part of an Honours study executed by Dwayne Pike under Heyns’ supervision. He is co-supervised by Dr Boucher who is assisting with the biochemical and microbiological assays.

Dr Boucher said, “Amphibians are characterised by the presence of cutaneous glands spread over the skin. There are two types of glands, namely mucous and granular (poison), located on the inner surface of the epidermis. Mucous glands are widely dispersed over the skin, while granular glands can be grouped and enlarged in specific regions. Mucous glands are generally associated with maintenance of humidity and cutaneous respiration, whereas granular glands function in chemical defence against predators and/or microbial infection. Studies indicate that the compounds produced by the granular glands belong to numerous chemical classes with diverse pharmacological activities.”

The products secreted by granular glands are rich in low molecular weight constituents of varied molecular types, including proteins, peptides and toxins. These secretions make the toad foul-tasting to predators and even toxic to other frog species. In addition, amphibians offer an attractive source of novel antimicrobials. Studies indicate that as a response to inhabiting microorganism-rich environments they synthesise and secrete a diverse array of antimicrobial peptides (AMPs) as an innate form of defence. Extensive research by various other research groups has been carried out on antimicrobial peptides of the genus Rana; however, hardly any studies have investigated the antimicrobial activity of African frog species.

The focus of this preliminary project is to determine the protein composition of the glandular secretions of the Western olive toad (Amietophrynus poweri), using biochemical tests, such as SDS-PAGE also known as protein gel electrophoresis combined with mass-spectrometry used to identify unknown peptides and proteins. This will give us an overview of the composition of the glandular secretions. Furthermore, we are also looking at microbiological tests, which include assays that test for possible anti-microbial activity against various bacterial and fungal species.

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