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Lebakeng soars: Allan Gray nominee and beacon of achievement

18 October 2024 | Story Precious Shamase | Photo Supplied

The University of the Free State (UFS) celebrates Lebakeng Mokhele, a remarkable student nominated for the prestigious Allan Gray Student Achievers programme. This recognition highlights Mokhele’s exceptional academic journey, fuelled by dedication and a commitment to making a difference.

Mokhele is a beneficiary of the Centre for Global Change, exemplifying the positive impact of the centre.

Triumph over adversity

Despite facing significant challenges during his first year, Mokhele persevered and achieved remarkable success. Starting his academic journey on foot and enduring seven months without electricity, he demonstrated exceptional discipline and dedication to his studies.

Using a candle for light, Mokhele diligently pursued his academic goals, ultimately earning the prestigious title of Best First-Year in the Department of Computer Science and Informatics. His achievement was even more impressive considering the obstacles he overcame. Mokhele's story serves as a testament to the power of perseverance and the importance of maintaining focus in the face of adversity.

Mokhele’s story is one of perseverance. Growing up, he wanted to become a medical doctor. He credits his mother as his unwavering pillar of support. Additionally, he acknowledges Dr Amon Magwiro and Annemarie van Noordwyk for their guidance and mentorship.

A Well-Rounded Achiever

Currently pursuing an Honours in Business Management, Mokhele has a list of impressive accomplishments:

Top achiever awards across various departments
Best academic performer among all students in 2019
Golden Key International Honour Society member
Best performer in the Department of Business Management in 2020

Ambitious Goals and Aspiring Vision

He aspires to earn a PhD in Business Management while simultaneously establishing a thriving mixed farming enterprise. The Allan Gray programme offers him an opportunity to network and gain exposure to the financial industry – a developing passion sparked by the COVID-19 pandemic.

Leadership and Community Focus

His dedication extends beyond academics. He is actively involved in extracurricular activities, including organising community soccer tournaments. He demonstrates strong leadership through his roles as:

President of Enactus UFS
Treasurer of Youth in Agriculture and Rural Development in Maluti-a-Phofung
His farming venture currently employs workers and plans for expansion are underway. Through his ‘bucks n bucks’ consultancy, he assists aspiring entrepreneurs.

Sharing his Wisdom

Mokhele emphasises the importance of applying knowledge and seeking information. He encourages fellow students:

Focus on discipline: It is the key to overcoming challenges.
Find your ‘why’: Drive yourself with a clear purpose.
Never give up: Success is possible even when facing setbacks.

Gratitude and Acknowledgement

Lebakeng expresses his deepest gratitude to his family, lecturers, the Centre for Global Change (including Prof Otomo and his team), and everyone who have supported him.

A Final Note

For those interested in learning more about Mokhele’s business venture, visit his website: www.bucksnbucks.co.za

News Archive

Nuclear Medicine on the forefront of cancer research

2017-07-10

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma. The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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