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19 September 2024 | Story Anthony Mthembu | Photo Anthony Mthembu
GEADO donates sanitary towels to community development initiative 2024
From left to right: Morwesi Malebo, Founder of ‘Give a Flower for a Change’, and Geraldine Lengau, Senior Officer in the Unit for Institutional Change and Social Justice at UFS.

As part of its ongoing Dignity Kit Awareness Campaign, launched in 2023, the Gender Equality and Anti-Discrimination Office (GEADO) at the University of the Free State (UFS) recently contributed to a community development initiative titled ‘Give a Flower for a Change.’ A batch of sanitary towels was recently officially handed over at the UFS Bloemfontein Campus, facilitated by Geraldine Lengau, Senior Officer in the Unit for Institutional Change and Social Justice.

According to Lengau, GEADO has made several similar donations on campus, benefitting initiatives such as the ‘No Student Hungry’ (NSH) programme, staff members through the Office of Organisational Development and Employee Wellness, as well as student walk-ins, among others. This latest donation extends the reach of the Dignity Kit Campaign beyond the campus community. ‘’This forms part of our mandate to raise awareness, particularly in uplifting the dignity of women. It is essential for the university to provide these dignity kits, as it demonstrates its commitment to addressing gender-based violence, supporting survivors, and promoting awareness,’’ said Lengau. She further emphasised that such donations foster a broader effort by the university to create a culture of respect, empathy, and support for surrounding communities, thus advancing social justice as articulated in the UFS’s Vision 130 strategic plan. 

Supporting Give a flower for a Change

The sanitary towels were handed over to Morwesi Malebo, founder of ‘Give a Flower for a Change’. According to Malebo, the initiative works closely with Unity Primary School in Bloemfontein, aiming to uplift the lives of children, particularly those from previously disadvantaged households. ‘’I have heard of instances at the school where some learners resorted to using cloth during their periods because they lacked access to sanitary towels,” Malebo shared. The donation will now help provide the necessary supplies to these children.

The initiative relies heavily on donations, accepting sanitary towels, school shoes, toiletries, and other essential items. Malebo stressed the significant impact of these contributions, noting that the learners are ‘’incredibly grateful, and the positive change in their lives is visible.” Without such resources, learners often feel self-conscious, which affects their performance at school. Collaborations with partners like GEADO, Malebo added, are crucial to the development of communities like hers. Consequently, she hopes to expand the initiative to high schools across Bloemfontein and maintain a strong partnership with GEADO.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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