Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
16 April 2025 | Story Andre Damons | Photo Kaleidoscope Studios
Ambrose du Plessis
Dr Ambrosé du Plessis, lecturer in the Department of Public Administration and Management, at his graduation of the University of the Free State (UFS) April graduation ceremonies.

With coalition governments becoming more common in South Africa and proven to be unstable, a lecturer at the University of the Free State (UFS) devised an alternative contextual coalition-led framework towards a functioning political-administrative dichotomy. This instability adversely affects service delivery. 

The framework was devised by Dr Ambrosé du Plessis, lecturer in the UFS Department of Public Administration and Management, as part of his PhD research and focused on the City of Johannesburg Metropolitan Municipality. He hopes it can offer valuable lessons for the broader context of South Africa’s evolving political landscape, particularly in light of the 2024 national coalition-led Government of national Unity (GNU). 

Dr Du Plessis graduated with a Doctor of Philosophy with specialisation in Public Administration and management at the UFS April graduation ceremonies. Prof Liezel Lues, Professor of Public Administration and Management, in the Department of Public Administration and Management, was his supervisor. 

Dr Du Plessis is part of the newest cohort of the Emerging Scholar Accelerator (ESAP) mentoring programme for mostly lecturers who are less than five years post-PhD. This group falls within the Transformation of the Professoriate Mentoring Programme which aims to grow a critical mass of excellent emerging scholars at the university who are equipped to assume senior academic and research positions. 

 

Political-administrative dichotomy

With his thesis titled ‘The Political-Administrative Dichotomy in coalition-led metropolitan municipalities: A South African Perspective’, he focuses on the interface between politics and administration. Says Dr Du Plessis: “The political-administrative dichotomy discourse is unable to account for coalition politics in most of South Africa’s metropolitan municipalities. More importantly, political and administrative instability has become common in most of South Africa’s coalition-led metropolitan municipalities.

“What makes my research particularly interesting is that it transcends Public Administration by incorporating contributions from Political Science through critical discourse analysis. I also conducted interviews with political office-bearers, the South African Local Government Association in Gauteng province, as well as subject experts – both national and international – in public administration, political science, and constitutionalism, to uncover deeper nuances relating to local lived experiences and international perspectives,” says Dr Du Plessis. 

According to him, the increasing prevalence of coalition-led governments in South Africa’s metropolitan municipalities necessitates a reconceptualisation of the political-administrative interface. Traditional interpretations of the political-administrative dichotomy have proved inadequate in explaining the multifaceted and dynamic interactions characteristic of contemporary coalition governance. This study responds to that gap by proposing a nuanced, context-sensitive, and theoretically enriched framework that better reflects the realities of coalition-led metropolitan municipal governance in the South African context.

 

The findings of the research 

“Building on comparative and critical discourse analyses, this research advances a polychotomous framework – one that transcends mono-theoretical and discipline-bound approaches by integrating insights from Public Administration and Political Science. The framework acknowledges the existence of both formal and informal political-administrative relationships and interrogates how these configurations influence governance outcomes in coalition-led municipalities, with specific reference to the City of Johannesburg (CoJ) Metropolitan Municipality.

“The findings underscore the limitations of classical dichotomy theory, particularly in accounting for the intersectionality between coalition politics and the institutional architecture of local government. In contrast to the dichotomy discourse, which narrowly focuses on political principals and administrative office-bearers, this research situates the interface within a broader institutional and societal matrix that includes political parties, non-state actors, and citizen constituencies.”

Dr Du Plessis say although this study was confined to local government and the CoJ, he believes it makes a meaningful knowledge contribution with real-world impact, paving the way for continued exploration and innovation in both research and practice concerning the political-administrative interface in coalition-led metropolitan municipalities. “More importantly, I hope it sparks critical reflection on the central nervous system of government and governance in South Africa, highlighting the urgent need to reconfigure not only political and administrative arrangements, but also the broader governance frameworks required to manage coalition politics effectively.”

 

PhD journey 

Obtaining his PhD, Dr Du Plessis says, is extremely emotional as he hopes to have inspired the broader family and future generations of students. It is both a liberating and proud moment for him for which he is deeply grateful and extremely overjoyed. This is not only the achievement of a personal and academic goal, but also the fulfilment of a journey filled with perseverance, growth, and purpose.

Like most PhDs, his journey was characterised by challenges that not only tested his intellectual ability but also his drive to succeed. There were moments of “profound loneliness”, self-doubt and even an overwhelming sense of guilt and shame. He had to deal with mental health challenges and experienced the well-known imposter syndrome. However, the support from his wife, Natasha, and Prof Lues, as well as colleagues like Dr Marevé Biljohn, Head of the Department of Public Administration and Management, the Faculty of Economic and Management Sciences PhD support group under the leadership of Prof Tina Kotze and Mrs Igna du Plooy and the REAP programme under the leadership of Dr Henriette van der Berg and Dr Karen Booysen, were essential in completing his PhD. They guided him through the academic and emotional trials of this journey with unwavering compassion.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept