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14 April 2025 | Story André Damons | Photo André Damons
Health Sciences Medal winners
Three of the Dean’s medal winners: Celine Taute, Angelique Johnson and Dr Monique Davidson after the graduation ceremony.

It was a big week for the newest University of the Free State (UFS) graduate, Angelique Johnson, who not only graduated with a Bachelor of Medical Science Honours in Pharmacology degree with distinction, but she was also awarded the Dean’s medal in the Faculty of Health Sciences at the university’s April graduation ceremonies.

Only a day before crossing the graduation stage on Friday 11 April, Angelique was also awarded the UFS Faculty of Health Sciences floating trophy for achieving the best results in respect of a bachelor honours degree in the faculty. 

“It’s honestly an honour. Receiving the Dean’s Medal feels surreal — it’s a reminder that the effort I put in didn’t go unnoticed. It’s also motivating and makes me feel proud to represent my faculty in such a positive way.

“Graduating with distinction feels incredibly rewarding — it’s a validation of all the late nights, hard work, and perseverance. Achieving this required discipline, time management, and a genuine passion for the material. I also leaned on a strong support system and made sure to stay consistent throughout the academic year,” says Angelique.

 

Dean’s Medal winners

The Dean’s medal was also awarded to Celine Taute, Alexander van Wyk and Dr Monique Davidson who all graduated last year. Taute, who graduated with a Bachelor of Medical Science with specialisation in Radiation Sciences degree (obtained with distinction), was awarded the Dean’s medal for achieving the best results as a third-year student. Van Wyk graduated with Bachelor of Biokinetics degree with distinction and received the Dean’s medal for achieving the best results as a fourth-year student while Dr Davidson received was awarded for obtaining the best results as a fifth-year student. 

Dr Davidson graduated with the degree Bachelor of Medicine and Bachelor of Surgery with distinction. Just like Johnson, Dr Davidson, Taute and Van Wyk was also awarded the faculty’s floating trophy for achieving the best results in their respective study years at Thursday’s (10 April 2025) prize-giving ceremony. 

 

Driven by passion 

According to Angelique, she will now pursue an MBChB degree as her passion for medicine drives her to go beyond simply making small changes — she wants to create a meaningful, lasting impact. “To borrow and adapt the words of Prof Gert van Zyl, Dean of the Faculty of Health Sciences, I don’t just aim to create ripples or waves in the field of healthcare — I aspire to create a tsunami of positive change in people’s lives and in the medical profession.”

In 2023 she completed a BSc in Human Physiology (cum laude) from the University of Pretoria (UP). She decided to enrol for an Honours in Pharmacology degree after developing a strong interest in how the body responds to different substances, especially at the cellular and molecular levels.

“Pharmacology felt like a natural extension of that curiosity — it dives deeper into the mechanisms of drug action and how they can be used to treat disease. I wanted to better understand how physiological processes can be manipulated for therapeutic benefit, and pharmacology offered the perfect balance between science and real-world medical application,” she concludes.

 

Provide comfort 

According to Celine, both the Dean’s medal as well as the awards came as a big surprise because she did not set out to achieve them. “I feel immensely blessed and thankful. Things that are worth it, require some sacrifices.” 

“I am so grateful. I set out to do my best and trusted that God would sort out the details. Discipline and hard work were key in my success. A person is not an island, so having family that always believed in me even when I didn't, helped me get through those tough exams,” says Celine. 

Celine, who is currently busy with an honour’s degree whereafter she will embark on a two-year internship, says she chose to specialise in radiation as she wanted to provide comfort and education to the mostly cancer patients and their families who radiation treatment can help.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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