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08 April 2025 | Story Precious Shamase | Photo Kaleidoscope Studios
Sellwane Moloi
Sellwane Jeanette Moloi celebrates graduating with a PhD in plant stress biology, contributing vital research toward global food security through drought-tolerant wheat studies.

Embarking on a PhD is a transformative journey, one filled with intellectual challenges, personal growth, and the potential to contribute meaningfully to one's field. For Sellwane Jeanette Moloi – who has graduated with her PhD on Friday 4 April during the afternoon session – the path was illuminated by a deep fascination with plants and a determination to address the critical issue of global food security.

 

A spark of curiosity

"The initial spark came from a deep curiosity about plants," Moloi shared. "I was intrigued by how plants function and the key mechanisms that help them survive when exposed to various environmental stress factors. Learning different techniques used to study and analyse plant responses to environmental factors made me even more intrigued." This curiosity fuelled a rigorous exploration into plant stress biology, focusing on how wheat thrives under drought conditions.

 

Navigating the challenges

Reflecting on the experience, however, the PhD journey was not without its hurdles. "One of the most challenging aspects was staying motivated and managing pressure," Moloi confessed. "Setbacks and slow progress can also be overwhelming." Overcoming these obstacles required a strategic approach: "I had to break down larger tasks into manageable tasks and also seek support from my supervisors."

Doubts inevitably arose, especially when experiments did not go as planned. "There were moments when I asked myself what I had actually gotten myself into," she admitted. However, the unwavering support of supervisors, colleagues, friends, and family provided the necessary reassurance. "They always assured me things would work out; I needed to hang in there."

 

Key discoveries and achievements

Amid the challenges, significant discoveries were made. Notably, Moloi found that a drought-tolerant wheat variety suppressed photosynthesis as a potential strategy to avert oxidative stress damage, maintaining cell membrane integrity during stressful conditions. This unexpected turn stressed the complexity of plant survival mechanisms.

Moloi’s dedication and hard work culminated in significant achievements, including winning the best PhD poster in plant physiology at the 46th South Africa Association of Botanists Conference in 2020, 3rd Prize at the University of Johannesburg Postgraduate Symposium in 2023 and publishing two research articles in high-impact journals. These accomplishments are a testament to her research prowess and contribution to the field.

 

Developing essential skills

Beyond the research itself, the PhD journey fostered critical skills vital for future success. ‘Critical thinking, logical reasoning, and problem-solving’ were highlighted as key takeaways. "As a PhD student, your mind is constantly engaged in critically analysing results and providing logical reasoning. I believe these skills are valuable in tackling certain situations and providing solutions to problems."

 

Balancing life and research

Balancing research with other aspects of life proved challenging. "That was challenging, but I created a schedule that worked for me," the graduand explained. "This included dedicating certain days (weekends or holidays) or hours to specific tasks, such as lab work or writing. One thing I would advise a PhD student is that they should make time to rest to avoid burnout."


Contribution to food security

Moloi's research holds significant implications for global food security, a pressing issue in the face of climate change and a growing population. "I hope my research will provide insight into how wheat as a cereal crop thrives under drought stress conditions, and the information can be used by plant breeding initiatives in developing more drought-tolerant crops," she stated. "The opportunity to contribute to the field of plant stress biology – my research focuses on understanding plant response mechanisms under drought, and acquiring such information can address issues related to global food security."


Advice for future PhD candidates

For students embarking on their PhD journey, Moloi offered valuable advice: "This degree requires one to be highly motivated and ask for help whenever there are setbacks. There will always be setbacks in research; you need to go back to the drawing board and look for solutions." She also emphasised the importance of seeking support for mental and emotional well-being. "It is okay to feel overwhelmed; the work can be too much at times. Students need to ask for help. We have professionals on campus who can assist with mental or emotional issues."

Furthermore, Moloi shared personal lessons: "Time management and prioritising important tasks. I also learned that it is important to allow yourself to rest. This degree can affect your mental or emotional health." And a candid reflection: "I did not have much of a social life, and I spent most of my time in the lab."

 

Looking ahead

With a PhD in hand, Moloi aspires to become an expert in her field, collaborating with other researchers and mentoring future students. Her journey exemplifies the dedication, resilience, and intellectual curiosity required to excel in academia and contribute to addressing pressing global challenges.

The university provided essential support throughout her studies, ensuring access to facilities even during the COVID-19 pandemic. "I always had access to the facilities on campus to do my research, even during the COVID-19 pandemic."

Celebrating milestones along the way was crucial, with fellow postgraduates sharing in each other's achievements. "My fellow postgraduates and I often went out for lunch to celebrate everyone's achievements." And the support system was extensive: "Everyone – family, supervisors, friends, and colleagues.”

News Archive

Heart diseases a time bomb in Africa, says UFS expert
2010-05-17

 Prof. Francis Smit

There are a lot of cardiac problems in Africa. Sub-Saharan Africa is home to the largest population of rheumatic heart disease patients in the world and therefore hosts the largest rheumatic heart valve population in the world. They are more than one million, compared to 33 000 in the whole of the industrialised world, says Prof. Francis Smit, Head of the Department of Cardiothoracic Surgery at the Faculty of Health Sciences at the University of the Free State (UFS).

He delivered an inaugural lecture on the topic Cardiothoracic Surgery: Complex simplicity, or simple complexity?

“We are also sitting on a time bomb of ischemic heart disease with the WHO (World Health Organisation) estimating that CAD (coronary artery disease) will become the number-one killer in our region by 2020. HIV/Aids is expected to go down to number 7.”

Very little is done about it. There is neither a clear nor coordinated programme to address this expected epidemic and CAD is regarded as an expensive disease, confined to Caucasians in the industrialised world. “We are ignoring alarming statistics about incidences of adult obesity, diabetes and endemic hypertension in our black population and a rising incidence of coronary artery interventions and incidents in our indigenous population,” Prof. Smit says.

Outside South Africa – with 44 units – very few units (about seven) perform low volumes of basic cardiac surgery. The South African units at all academic institutions are under severe threat and about 70% of cardiac procedures are performed in the private sector.

He says the main challenge in Africa has become sustainability, which needs to be addressed through education. Cardiothoracic surgery must become part of everyday surgery in Africa through alternative education programmes. That will make this specialty relevant at all levels of healthcare and it must be involved in resource allocation to medicine in general and cardiothoracic surgery specifically.

The African surgeon should make the maximum impact at the lowest possible cost to as many people in a society as possible. “Our training in fields like intensive care and insight into pulmonology, gastroenterology and cardiology give us the possibility of expanding our roles in African medicine. We must also remember that we are trained physicians as well.

“Should people die or suffer tremendously while we can train a group of surgical specialists or retraining general surgeons to expand our impact on cardiothoracic disease in Africa using available technology maybe more creatively? We have made great progress in establishing an African School for Cardiothoracic Surgery.”

Prof. Smit also highlighted the role of the annual Hannes Meyer National Registrar Symposium that culminated in having an eight-strong international panel sponsored by the ICC of EACTS to present a scientific course as well as advanced surgical techniques in conjunction with the Hannes Meyer Symposium in 2010.

Prof. Smit says South Africa is fast becoming the driving force in cardiothoracic surgery in Africa. South Africa is the only country that has the knowledge, technology and skills base to act as the springboard for the development of cardiothoracic surgery in Africa.

South Africa, however, is experiencing its own problems. Mortality has doubled in the years from 1997 to 2005 and half the population in the Free State dies between 40 to 44 years of age.

“If we do not need health professionals to determine the quality and quantity of service delivery to the population and do not want to involve them in this process, we can get rid of them, but then the political leaders making that decision must accept responsibility for the clinical outcomes and life expectancies of their fellow citizens.

“We surely cannot expect to impose the same medical legal principles on professionals working in unsafe hospitals and who have complained and made authorities aware of these conditions than upon those working in functional institutions. Either fixes the institutions or indemnifies medical personnel working in these conditions and defends the decision publicly.

“Why do I have to choose the three out of four patients that cannot have a lifesaving operation and will have to die on their own while the system pretends to deliver treatment to all?”

Prof. Smit says developing a service package with guidelines in the public domain will go a long way towards addressing this issue. It is also about time that we have to admit that things are simply not the same. Standards are deteriorating and training outcomes are or will be affected.

The people who make decisions that affect healthcare service delivery and outcomes, the quality of training platforms and research, in a word, the future of South African medicine, firstly need rules and boundaries. He also suggested that maybe the government should develop health policy in the public domain and then outsource healthcare delivery to people who can actually deliver including thousands of experts employed but ignored by the State at present.

“It is time that we all have to accept our responsibilities at all levels… and act decisively on matters that will determine the quality and quantity of medical care for this and future generations in South Africa and Africa. Time is running out,” Prof. Smit says.
 

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