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08 April 2025 | Story Precious Shamase | Photo Kaleidoscope Studios
Sellwane Moloi
Sellwane Jeanette Moloi celebrates graduating with a PhD in plant stress biology, contributing vital research toward global food security through drought-tolerant wheat studies.

Embarking on a PhD is a transformative journey, one filled with intellectual challenges, personal growth, and the potential to contribute meaningfully to one's field. For Sellwane Jeanette Moloi – who has graduated with her PhD on Friday 4 April during the afternoon session – the path was illuminated by a deep fascination with plants and a determination to address the critical issue of global food security.

 

A spark of curiosity

"The initial spark came from a deep curiosity about plants," Moloi shared. "I was intrigued by how plants function and the key mechanisms that help them survive when exposed to various environmental stress factors. Learning different techniques used to study and analyse plant responses to environmental factors made me even more intrigued." This curiosity fuelled a rigorous exploration into plant stress biology, focusing on how wheat thrives under drought conditions.

 

Navigating the challenges

Reflecting on the experience, however, the PhD journey was not without its hurdles. "One of the most challenging aspects was staying motivated and managing pressure," Moloi confessed. "Setbacks and slow progress can also be overwhelming." Overcoming these obstacles required a strategic approach: "I had to break down larger tasks into manageable tasks and also seek support from my supervisors."

Doubts inevitably arose, especially when experiments did not go as planned. "There were moments when I asked myself what I had actually gotten myself into," she admitted. However, the unwavering support of supervisors, colleagues, friends, and family provided the necessary reassurance. "They always assured me things would work out; I needed to hang in there."

 

Key discoveries and achievements

Amid the challenges, significant discoveries were made. Notably, Moloi found that a drought-tolerant wheat variety suppressed photosynthesis as a potential strategy to avert oxidative stress damage, maintaining cell membrane integrity during stressful conditions. This unexpected turn stressed the complexity of plant survival mechanisms.

Moloi’s dedication and hard work culminated in significant achievements, including winning the best PhD poster in plant physiology at the 46th South Africa Association of Botanists Conference in 2020, 3rd Prize at the University of Johannesburg Postgraduate Symposium in 2023 and publishing two research articles in high-impact journals. These accomplishments are a testament to her research prowess and contribution to the field.

 

Developing essential skills

Beyond the research itself, the PhD journey fostered critical skills vital for future success. ‘Critical thinking, logical reasoning, and problem-solving’ were highlighted as key takeaways. "As a PhD student, your mind is constantly engaged in critically analysing results and providing logical reasoning. I believe these skills are valuable in tackling certain situations and providing solutions to problems."

 

Balancing life and research

Balancing research with other aspects of life proved challenging. "That was challenging, but I created a schedule that worked for me," the graduand explained. "This included dedicating certain days (weekends or holidays) or hours to specific tasks, such as lab work or writing. One thing I would advise a PhD student is that they should make time to rest to avoid burnout."


Contribution to food security

Moloi's research holds significant implications for global food security, a pressing issue in the face of climate change and a growing population. "I hope my research will provide insight into how wheat as a cereal crop thrives under drought stress conditions, and the information can be used by plant breeding initiatives in developing more drought-tolerant crops," she stated. "The opportunity to contribute to the field of plant stress biology – my research focuses on understanding plant response mechanisms under drought, and acquiring such information can address issues related to global food security."


Advice for future PhD candidates

For students embarking on their PhD journey, Moloi offered valuable advice: "This degree requires one to be highly motivated and ask for help whenever there are setbacks. There will always be setbacks in research; you need to go back to the drawing board and look for solutions." She also emphasised the importance of seeking support for mental and emotional well-being. "It is okay to feel overwhelmed; the work can be too much at times. Students need to ask for help. We have professionals on campus who can assist with mental or emotional issues."

Furthermore, Moloi shared personal lessons: "Time management and prioritising important tasks. I also learned that it is important to allow yourself to rest. This degree can affect your mental or emotional health." And a candid reflection: "I did not have much of a social life, and I spent most of my time in the lab."

 

Looking ahead

With a PhD in hand, Moloi aspires to become an expert in her field, collaborating with other researchers and mentoring future students. Her journey exemplifies the dedication, resilience, and intellectual curiosity required to excel in academia and contribute to addressing pressing global challenges.

The university provided essential support throughout her studies, ensuring access to facilities even during the COVID-19 pandemic. "I always had access to the facilities on campus to do my research, even during the COVID-19 pandemic."

Celebrating milestones along the way was crucial, with fellow postgraduates sharing in each other's achievements. "My fellow postgraduates and I often went out for lunch to celebrate everyone's achievements." And the support system was extensive: "Everyone – family, supervisors, friends, and colleagues.”

News Archive

New world-class Chemistry facilities at UFS
2011-11-22

 

A world-class research centre was introduced on Friday 18 November 2011 when the new Chemistry building on the Bloemfontein Campus of the University of the Free State (UFS) was officially opened.
The upgrading of the building, which has taken place over a period of five years, is the UFS’s largest single financial investment in a long time. The building itself has been renovated at a cost of R60 million and, together with the new equipment acquired, the total investment exceeds R110 million. The university has provided the major part of this, with valuable contributions from Sasol and the South African Research Foundation (NRF), which each contributed more than R20 million for different facets and projects.
The senior management of Sasol, NECSA (The South African Nuclear Energy Corporation), PETLabs Pharmaceuticals, and visitors from Sweden attended the opening.

Prof. Andreas Roodt, Head of the Department of Chemistry, states the department’s specialist research areas includes X-ray crystallography, electrochemistry, synthesis of new molecules, the development of new methods to determine rare elements, water purification, as well as the measurement of energy and temperatures responsible for phase changes in molecules, the development of agents to detect cancer and other defects in the body, and many more.

“We have top expertise in various fields, with some of the best equipment and currently competing with the best laboratories in the world. We have collaborative agreements with more than twenty national and international chemistry research groups of note.

“Currently we are providing inputs about technical aspects of the acid mine water in Johannesburg and vicinity, as well as the fracking in the Karoo in order to release shale gas.”

New equipment installed during the upgrading action comprises:

  • X-ray diffractometers (R5 million) for crystal research. Crystals with unknown compounds are researched on an X-ray diffractometer, which determines the distances in angstroms (1 angstrom is a ten-billionth of a metre) and corners between atoms, as well as the arrangement of the atoms in the crystal, and the precise composition of the molecules in the crystal.
  • Differential scanning calorimeter (DSC) for thermographic analyses (R4 million). Heat transfer and the accompanying changes, as in volcanoes, and catalytic reactions for new motor petrol are researched. Temperature changes, coupled with the phase switchover of fluid crystals (liquid crystals -watches, TV screens) of solid matter to fluids, are measured.
  • Nuclear-magnetic resonance (NMR: Bruker 600 MHz; R12 million, one of the most advanced systems in Africa). A NMR apparatus is closely linked with the apparatus for magnetic resonance imaging, which is commonly used in hospitals. NMR is also used to determine the structure of unknown compounds, as well as the purity of the sample. Important structural characteristics of molecules can also be identified, which is extremely important if this molecule is to be used as medication, as well as to predict any possible side effects of it.
  • High-performance Computing Centre (HPC, R5 million). The UFS’ HPC consists of approximately 900 computer cores (equal to 900 ordinary personal computers) encapsulated in one compact system handling calculations at a billion-datapoint level It is used to calculate the geometry and spatial arrangements, energy and characteristics of molecules. The bigger the molecule that is worked with, the more powerful the computers must be doing the calculations. Computing chemistry is particularly useful to calculate molecular characteristics in the absence of X-ray crystallographic or other structural information. Some reactions are so quick that the intermediary products cannot be characterised and computing chemistry is of invaluable value in that case.
  • Catalytic and high-pressure equipment (R6 million; some of the most advanced equipment in the world). The pressures reached (in comparison with those in car tyres) are in gases (100 times bigger) and in fluids (1 500 times) in order to study very special reactions. The research is undertaken, some of which are in collaboration with Sasol, to develop new petrol and petrol additives and add value to local chemicals.
  • Reaction speed equipment (Kinetics: R5 million; some of the most advanced equipment in the world). The tempo and reactions can be studied in the ultraviolet, visible and infrared area at millisecond level; if combined with the NMR, up to a microsecond level (one millionth of a second.

Typical reactions are, for example, the human respiratory system, the absorption of agents in the brain, decomposition of nanomaterials and protein, acid and basis polymerisation reactions (shaping of water-bottle plastic) and many more.

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