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08 April 2025 | Story Precious Shamase | Photo Supplied
Sifiso Banda
Sifiso Banda balances library duties and academic goals, showcasing innovation and resilience at the UFS Qwaqwa Campus.

In the heart of the University of the Free State Qwaqwa Campus, Sifiso Banda's story is one of ambition, and the seamless fusion of seemingly disparate worlds. Balancing his role as Senior Assistant Officer: Circulations and TK Mopeli Makerspace in the library with the rigorous demands of a BSc Honours Degree in Computer Science, Banda has not only excelled but also inspired.

 

Overcoming challenges fuelled by dreams

"Computer Science is my primary passion," Banda explains, his voice resonating with determination. "Being in academia allows me to interact with ever-evolving technologies. I love problem-solving and creating new ideas to help my community. “However, the path was far from easy. Juggling a demanding job with intense academic pressure led to sleepless nights and near-burnout. "It required immense professionalism in time planning and management," he confesses. "I almost gave up, but the unwavering support of my colleagues and supervisors kept me going."

Banda's journey is a testament to the power of perseverance, fuelled by a deep sense of responsibility and gratitude. "I had to remind myself daily who I was doing this for," he says, his voice filled with emotion. "My late mother used her last savings to register me for university, giving me an opportunity she never had. That memory pushed me through the pain."

 

From theory to practice: Innovating library technology

His unique position within the library has provided an unexpected synergy with his Computer Science studies. "I saw a gap to bridge theory with practical application," Banda explains. "I want to use my tech skills to innovate and make education engaging, developing systems and apps that simplify student life."

He discovered that library science extends far beyond traditional book management. "It's not just borrowing and cataloguing," he says. "There are diverse career paths for a computer scientist, such as systems librarian."

Banda's practical application of his computer science knowledge is evident in his daily work. He plays a key role in managing and configuring the library's technology, including RFID self-check machines and automated chutes. Notably, a YouTube demonstration he created showcases his ability to bridge the digital divide for library users.

The most daunting challenge was his mini-dissertation. "It demanded immense time, often encroaching on my work hours," he recalls. "Balancing coding, documentation, and assisting patrons was incredibly difficult."

 

Evolving technology and support

His fascination with computer science stems from its dynamic nature. "Technology evolves daily," he says. "I'm particularly drawn to artificial intelligence and machine learning, as I envision a future where everything is digitised. My childhood dream was to build robots that could assist in households."

Banda credits several mentors for their profound impact on his academic journey. Prof Richard Ocaya, Prof Lehlohonolo Koao, Dr Andronicus Akinyelu, and Adebola Musa all provided crucial guidance and support. He also acknowledges the invaluable emotional support from Nonhlanhla Moleleki, a counsellor, and Khethiwe Bhiyo, his academic adviser. "The community at large played a vital role," he emphasises.

His advice to students working while studying is simple yet powerful: "Everything is possible with consistency, persistence, determination, and dedication. Keep focused, no matter how long it takes."

His research project, an online dining hall purchasing system, exemplifies his commitment to community-driven innovation. "It has reduced wait times and queues across our campuses," he says proudly.

Looking ahead, Banda plans to pursue a master's degree, aiming to combine his library experience with his technical expertise. "I envision libraries becoming increasingly digitised, and I want to be part of that evolution," he states.

The skills he gained – time management, multitasking, collaboration, and the courage to seek help – will be invaluable in his future endeavours. "Most importantly, believe in yourself," he concluded.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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