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09 April 2025 | Story Anthony Mthembu | Photo Supplied
Divine Wayela Bitalo
Divine Bitalo, Counselling Psychologist and PhD student at the University of the Free State (UFS), graduates with a Master of Social Science in Counselling Psychology during the UFS April 2025 graduations.

In what she describes as the result of ‘’being curious enough to see if it will all work out’’, Divine Bitalo, Counselling Psychologist and PhD student at the University of the Free State (UFS), is set to walk across the graduation stage in the Callie Human Centre on 9 April 2025. Bitalo will receive her Master of Social Science in Counselling Psychology, joining three other students in her category during the April graduation ceremony. 

 

A journey through rejection and reflection 

While this milestone is one of great joy and fulfilment, it follows three challenging years marked by repeated rejections. Bitalo shared that she had applied to several institutions for a place in a master's programme – but each application was met with disappointment. 

“That period made me question my inherent worth and whether I was meant to be doing the work which I so deeply wanted to do,’’ she recalled.  The impact on her mental health was profound, as she could not practice as a Counselling Psychologist without a master’s qualification. 

Everything changed when she received her acceptance letter from the UFS. That moment, she said, was filled with immense gratitude and marked the turning point in her academic and personal journey.   

 

Lessons from a season of waiting 

Bitalo believes the setbacks taught her valuable life lessons. “It shattered the mentality that there’s only one way to achieve your goals or live your life,” she said. ‘’Had I moved straight from my honours to my master’s, I would have retained that rigid thinking -  and I don’t think I would have developed the capacity to understand that human beings are fallible.” 

She went on to share a deeply personal insight: “There is no one scripture, no single speech, or perfect word of encouragement that can magically fix everything. Sometimes, we just have to sit with the uncertainty and wait to see if we make it.” 

The period of waiting, she said, also shaped the kind of professional she is becoming. “The patients I now see benefit from a better version of me - one who has walked through uncertainty and has come out stronger on the other side.”  

 

Research, recognition and a PhD

As part of her master’s programme, Bitalo produced a research thesis titled Fatherhood, manhood, and personhood: South African fathers’ experiences of parental identity development. The study, which has since been published by Taylor & Francis, explores how South African men understand and interpret fatherhood. 

‘’There was a time when fatherhood was primarily about provision and protection. Today, a new generation of fathers is bringing tenderness and emotional care into the role,” she explained. “My study looks at how we can marry these two approaches.’’ 

Now having completed her master’s degree, Bitalo is already working towards a PhD focused on emerging adulthood, with particular attention to the markers of adulthood in the South African context.

Looking back, she views her graduation as a powerful symbol of resilience and faith. “Walking across that stage represents more than just academic achievement – it’s proof that sometimes things really do work out, even when everything around you suggests otherwise.”  

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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