Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
30 April 2025 | Story Leonie Bolleurs | Photo Supplied
Dr Palesa Mohajane
Dr Palesa Mohajane, scientist production at the Department of Water and Sanitation, received her PhD from the UFS for her research on the impact of pandemic-related burials on groundwater quality.

Dr Palesa Mohajane, a scientist production at the Department of Water and Sanitation in Hartbeespoort, was recently awarded her doctoral degree at the University of the Free State’s (UFS) autumn graduation ceremony. Her thesis, titled Modelling the effect of pandemic-induced burials on groundwater contamination: a hydrogeological and epidemiological assessment, looks at the impact of increased burial rates on groundwater quality.

 

Safeguarding groundwater resources

Dr Mohajane explains that witnessing the dramatic rise in burial rates during the COVID-19 pandemic – including instances of mass burials – and the resulting strain on cemeteries, raised concerns about the potential risk of groundwater contamination. This became a motivator for her research.

Her study bridges the gap between environmental science and epidemiology, developing tools to predict how disease outbreaks and related deaths can impact groundwater systems. “By focusing on this intersection, the study contributes knowledge that informs not only responsible cemetery management, but also the protection of groundwater resources important to public health,” she says.

Dr Mohajane highlights the environmental risks that come with an increase in burial activity during pandemics. “When death rates rise sharply, cemeteries experience a surge in burials, which accelerates decomposition within confined spaces. As bodies decompose, they release organic and inorganic pollutants, which can seep through geological layers and affect groundwater quality.”

She notes that if cemeteries are established without proper hydrogeological assessments, these substances can infiltrate the soil and contaminate water sources, posing a threat to both environmental and human health.

 

Using advanced tools to predict groundwater pollution

Dr Mohajane conducted her research during the post-pandemic period when the longer-term environmental effects of COVID-19-related burial practices began to surface. “Groundwater sampling and quality testing were conducted between September 2023 and January 2024. This period provided a suitable time frame to monitor contaminant release and assess the hydrochemical effects of the burial practices,” she explains.

Langberg Cemetery was selected as a case study due to its representative geological and human-made characteristics, making it a strong candidate for validating the research models. “This site allowed for real-world testing of the mathematical models and simulations, offering important insights into how contaminants move through soil and rock layers and impact groundwater,” says Dr Mohajane.

Her findings revealed that groundwater contamination is influenced by multiple interacting factors – including burial depth, body mass, and geological features. She explains that shallower burials allow pollutants to reach the water table more rapidly, while deeper burials may delay but not prevent eventual leaching. Larger body masses produce more decomposing material, increasing the number of pollutants released. Geological conditions such as fractures and varied rock formations also play a role in the spread of contaminants.

Dr Mohajane’s work has serious implications for both public health and water sustainability. The presence of elevated levels of total dissolved solids, electrical conductivity, specific ions, alkalinity, and mineralisation indicates potential health hazards. As groundwater is an important source of drinking water, she stresses the urgency of addressing these risks. “We need to use advanced tools to predict and prevent groundwater pollution before it occurs. With proper water management systems, we can reduce the environmental impact of pandemics,” she says.

She also emphasises the importance of continuous monitoring to detect pollutant levels that exceed safety limits. “Improving burial practices – including thorough geological assessments before establishing cemeteries and optimising burial depths – can help reduce contaminant migration. These measures are important to protect community water resources,” she adds.

 

Measures to protect groundwater and public health

Dr Mohajane’s research proposes a range of practical measures to safeguard groundwater and public health. Cemeteries should only be developed after detailed geological evaluations, and clear regulations must guide cemetery design to manage increased burial needs during pandemics. Regular water quality monitoring using modern detection tools is key, along with the inclusion of environmental assessments in public health planning.

“These policy measures, if adopted at both regional and national levels, can help to reduce the risk of groundwater pollution and support long-term public health,” she says.

Ultimately, this research supports South Africa’s efforts to protect its groundwater by encouraging collaboration between scientists and policy makers. It offers predictive tools, evidence-based guidelines for sustainable cemetery management, and highlights how scientific research can shape practical, effective policies. The goal is to ensure that groundwater remains a safe and secure resource during future public health and environmental crises.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept