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22 April 2025 | Story André Damons | Photo Supplied
Dr Tafadzwa Maramura
Dr Tafadzwa Clementine Maramura is a Senior Lecturer and NRF-Rated Researcher in the Department of Public Administration and Management at the UFS.

With roughly half the world’s population experiencing severe water scarcity for at least part of the year, according to the UN World Water Development Report 2024, a researcher from the University of the Free State (UFS) seeks to understand how South Africa and the rest of the African continent can ensure that every person has access to water.

Besides Dr Tafadzwa Clementine Maramura, Senior Lecturer and NRF-Rated Researcher in the Department of Public Administration and Management at the UFS, research focusing on service delivery, especially delivery of water to the most vulnerable and poorest households, her work also focuses on the water-health nexus. In February she was appointed the Secretary for the Institutional Governance and Regulations Framework – a sub-specialist group for the International Water Association (IWA), becoming the first black African female to be appointed to this position.

According to statistics quoted by Greenpeace, 5.52 billion people out of a population of 7.78 billion in 186 countries face water insecurity, of which, 1.34 billion are Africans, accounting for more than 90% of the continent’s population. The United Nations World Water Development Report 2024: water for prosperity and peace; facts, figures, and action examples state that as of 2022, 2.2 billion people were without access to safely managed drinking water.

 

Research focus

With this, and with the Sustainable Development Goals (SDGs) – especially Goal 6 (clean water and sanitation) – in mind, Dr Maramura seeks to understand how South Africa and the rest of Africa can ensure that everyone gets access to this particular resource. “My research focuses on water governance and sustainable service delivery, public policies, and the green economy in the African, as well as the South African, context. What I found is interesting and really saddening at the same time. When you break it down, you realise that one in every three people in Africa don’t have access to potable water.

“Water is a basic human right, you can survive without electricity and other luxuries, but not without water. Each time you brush your teeth or flush your toilet with at least 15 litres of clean water or you are watering your garden with clean water, there are people that actually don’t have access to basic drinking water,” says Dr Maramura.

She is also investigating what the government is doing to ensure it delivers on this service it is mandated to, as South Africa has all the policies in place, and the best constitution in the world, but still the poor and most vulnerable communities do not have water.

“Access to clean water is not just a basic need; it is a matter of dignity, equality, and survival. As a young African woman, through my research, I see first-hand how the burden of water scarcity falls disproportionately on women and girls, robbing us as women, of education, economic opportunities, and health.

“But we are not just victims – we are leaders in this fight. By empowering women and investing in sustainable water solutions, we can transform our communities and break the cycle of poverty. The time for action is now because water is life, and every African deserves it.”

 

The water-health nexus

Dr Maramura has book chapters coming out in June this year that focus on the water-health nexus in failed states, thereby merging SDG 3 and 6 on health and water respectively. Water plays an indispensable role in the world as it is important for accomplishing several other SDGs, such as zero hunger, poverty eradication, good health and well-being, and affordable and clean energy. It all depends on the achievement of goal 6.

Says Dr Maramura: “You cannot solve problems in isolation; you cannot look at the water problem in isolation. If you have a water problem, you have a health and education problem because kids can’t go to school if there is no water. Hospitals can’t function when there is no water.

“SDG 3 speaks to health and SDG 6 speaks to water and that is where the nexus is, nexus meaning connection between water and health. How can we ensure that we merge the two together and ensure researchers working on health and water can find common ground to address any challenges arising from the lack of water so that we don’t have these health issues?”

South Africa is an upper-middle-income country but still struggles to deliver potable water to everyone and many communities in the country still rely on ventilated pit latrines due to limited access to modern sanitation facilities. With the deadline for achieving the 17 SDGs only five years away, South Africa is at risk of failing to achieve the SDGs.

 

Solving the water problems

According to Dr Maramura, there is no magic wand that can be used to solve all the country's water problems, but a collaborative and comprehensive effort is needed. “There is work that needs to be done. The government, private sector, the communities, as well as other role players need to work together. South Africa is a water-stressed country with rainfall below the global average. We realised that we have scarce groundwater resources.

“The community needs to understand, participate, and be aware of how much damage we can do by just drilling boreholes and digging wells. The private sector needs to know what it is that they can do to ensure that they also play a part through their corporate social responsibility and philanthropic dimensions in assisting the community.”

From the government side, she says, the policies are there so the government needs to consult with the communities, the private sector, and all other relevant stakeholders. They need to involve affected communities and after consultations, they need to engage these communities because they understand their problem best.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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