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04 April 2025 | Story Andre Damons | Photo Supplied
Prof Wayne Truter
Prof Wayne Truter, Research Professor at the UFS Centre for Mineral Biogeochemistry, and Executive Management of the UFS Green Futures Hub.

Hosting the South African Circular Agriculture Initiative (SACAI) – an initiative of the Department of Science, Technology and Innovation’s (DSTI) – will help position the Green Futures Hub at the University of the Free State (UFS) as a leader in circularity in agriculture.

The UFS Green Futures Hub was selected to host the SACAI from 1 January 2025-31 March 2026. The funding received will be used to conduct workshops with stakeholders to develop a strategy to strengthen South Africa’s science, technology, and innovation for a circular economy in the agriculture sector.

The SACAI, under the leadership of Prof Wayne Truter, Research Professor at the UFS Centre for Mineral Biogeochemistry, and Executive Management of the UFS Green Futures Hub, aims to advance the principles of the circular economy and modernise agriculture in line with the South African government's aspirations. These goals are outlined in the Science, Technology, and Innovation (STI) Decadal Plan (2022-2032) and the Circular Economy STI Strategy.

 

Elevating the UFS’ visibility

The UFS Green Future Hub is a virtual platform in the Faculty of Natural and Agricultural Sciences (NAS), to facilitate integration and leverage capabilities to facilitate third stream funding and industry collaboration. It provides an interface and support structure for researchers to engage with funders and partners through the Hub.

Prof Truter says it is a great honour and privilege to have been awarded this initiative. “The funding that comes with SACAI will elevate our visibility in agriculture in the country and will help position Green Futures Hub as a leader in circularity in agriculture. A key objective of SACAI is to leverage science, technology, and innovation to enhance the value of the national system of innovation (NSI) within the agriculture sector. 

“The initiative will align with the priorities set out in the Circular Economy STI Strategy (2024-2034), focusing on resource efficiency, regenerative agriculture, sustainable agro-processing, and biorefinery development in South Africa. Through collaborations with other public research institutions, the hub will drive STI implementation in these critical areas,” says Prof Truter.

 

Objectives of SACAI 

The objective of SACAI is to give effect to the (i) circular economy, and (ii) modernising agriculture, aspirations of the South African government. The SACAI aims to advance the principles of the circular economy and modernise agriculture in line with the South African government’s aspirations. 

Simultaneously, Prof Truter explains, the objectives of the SACAI align with the vision of the UFS Green Futures Hub to be a global leader in advancing the understanding and application of sustainable practices for life with land and water, in developing contexts. By leveraging the latest advancements in research, technology, and innovation, the hub aims to create a thriving future where communities harmonise with natural and agricultural environments, ensuring the well-being of current and future generations, which has a particular focus on modernising agriculture and capacity development. 

Through STI, the SACAI will support the South African agriculture sector to adopt, scale and accelerate circular practices and technology. The SACAI will act through a hub-and-spoke model, to build and strengthen a national system of innovation, and associated capability, and will establish and strengthen strategic regional and international STI partnerships, to directly support industry and other sector stakeholders, serving as a facilitator of relevant research and related outputs.

 

UFS’ Vision 130 

“A South African Circular Agricultural Initiative perfectly aligns with our research-led, student-centred, and regionally engaged university by driving innovation and knowledge production in sustainable agriculture. This initiative will enable the university to contribute to development and social justice by advancing circular farming practices that reduce waste, optimise resources, and promote environmental sustainability, particularly in rural areas. 

“This fosters greater food security and resilience, benefiting marginalised communities, and addressing social inequalities within the agricultural sector. By involving our students, this initiative will directly support the student-centred approach, offering hands-on learning experiences that equip graduates with cutting-edge skills in circular economy principles,” says Prof Truter. 

The university’s Vision 130 focus on diversity, inclusion, and equity is reflected in the initiative’s emphasis on sharing knowledge and resources equitably, ensuring maximum societal impact and advancing a more just and sustainable agricultural system across South Africa.

Prof Vasu Reddy, UFS Deputy Vice-Chancellor: Research and Internationalisation, says: “This accolade speaks volumes of the calibre of our scholars and the recognition of our expertise in the agricultural domain. The UFS is exceptionally proud of Prof Truter’s drive, initiatives, vision and foresight. Under his leadership, we will augment and inflect even further our standing and position in the circular economy of agriculture. Reddy added: “We will not simply be the heartland but the growing soul and substance of what agriculture might become through research, implementation and impact. We are watching this space with deep curiosity.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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