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04 April 2025 | Story Precious Shamase | Photo Supplied
Robson Nkosi
Robson Nkosi in his academic regalia at the graduation for his honours degree.

Robson Siphosihle Nkosi's journey is a compelling narrative of resilience, determination, and academic achievement – a story that resonates deeply within the University of the Free State (UFS) community. Born in Mpumalanga and raised under challenging circumstances, Nkosi's path to academic success is a testament to his unwavering spirit.

 

Unwavering determination

His early life was marked by significant loss, having been raised initially by his grandmother, and subsequently by his mother, who tragically passed away just before his final year of high school at Bee Maseko Secondary School, a quintile 1 school in Sheepmoor, Mpumalanga. Facing financial hardship, he relied on the support of friends to complete his matriculation.

Despite these adversities, Nkosi's determination shone through. With the invaluable assistance of his high school teacher, Mokoena Libakiso – whom he now considers his mother – he applied to the UFS to pursue a teaching degree. Although initially accepted, funding delays resulted in his offer being withdrawn. Securing funding later, he enrolled in a BSocSci degree, majoring in Communication Science and Sociology, demonstrating his adaptability and commitment to higher education.

Nkosi’s initial aspiration to switch to a Bachelor of Education degree was redirected by the NSFAS N+1 rule. However, he refocused his goals, setting his sights on a PhD and a career in higher education lecturing. This strategic vision fuelled his academic pursuits.


Leadership. Excellence. PhD.

His leadership skills were honed during his final undergraduate year, serving as the Qwaqwa Campus SRC Deputy President and ISRC Treasurer General. His academic excellence was consistently recognised through academic merit bursaries and the UFS Partial Tuition Fee Bursary, which supported his honours studies. Living in Botshabelo and commuting to Bloemfontein, Nkosi demonstrated his dedication.

During his honours year, he not only excelled as a student, but also as a tutor and Career Ambassador. His academic prowess led to an invitation from his honours lecturer, Yzelle Du Plessis, to facilitate Communication Science classes. He completed his honours degree cum laude, specialising in Leadership Communication.

Nkosi's academic journey continued with a master’s in communication science, funded by the National Research Foundation (NRF). Simultaneously, he gained practical teaching experience as a junior lecturer. He recently completed his master's degree and is now pursuing a PhD in Communication Science, while continuing to teach final-year and honours students on the Bloemfontein Campus.


A life dedicated to education and leadership

His short-term goal is to secure a permanent lecturing position, while his long-term ambition is to become a professor of Communication Science and potentially assume a leadership role in higher education, the public sector, or civil society.

Robson Nkosi's story is a powerful example of resilience, academic excellence, and the transformative impact of education. His dedication and gratitude to those who supported him underscore the importance of community and mentorship. He stands as an inspiration to the UFS community, demonstrating that with determination and perseverance, even the most challenging circumstances can be overcome.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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