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24 April 2025 | Story Martinette Brits | Photo Barend Nagel
Mainstream Final Project
Five postgraduate students from Ethiopia and Togo with Prof Corli Witthuhn, coordinator of the MAINSTREAM project, during their academic exchange visit to the University of the Free State. From the left: Prudence Bilabina, Ame Houngo, Prof Corli Witthuhn, Gemedo Shengu, Fanny Sibabi, and Debela Bedada.

The University of the Free State (UFS) has welcomed a cohort of international students as part of the Mobility 4 Agricultural International Networks Supporting Thematic Resilience and Enhancing Adaptation and Mitigation (MAINSTREAM) project, a significant European Union-funded initiative aimed at boosting agricultural education and research across the African continent.

A group of postgraduate students from Togo and Ethiopia have recently joined the University of the Free State as part of the MAINSTREAM project. “Two doctoral students from Togo – Ame Houngo and Fanny Sibabi – are based in the Department of Sustainable Food Systems and Development and will be supervised by Dr Alba du Toit and Prof Maryke Labuschagne,” says Prof Corli Witthuhn from the Department of Sustainable Food Systems and Development at the UFS, who serves as the coordinator of the MAINSTREAM project. Master’s student Prudence Bilabina, also from Togo, is hosted by the Department of Agricultural Economics under the supervision of Prof Henry Jordaan.

From Ethiopia, doctoral student Debela Bedada and master’s student Gemedo Shengu are both pursuing their research in the Department of Agricultural Economics, supervised by Prof Nicky Matthews and Dr Janus Henning respectively.

A Ugandan student will soon join them on 22 April for a three-month traineeship. “He is an undergraduate Agriculture student who will register for a service-learning module at the UFS and spend the three months working on a farm,” explains Prof Witthuhn. The student hails from the Mountains of the Moon University in Uganda.

By June 2025, the university anticipates the arrival of four more students from Uganda – three at master’s level and one traineeship participant – bringing the total number of MAINSTREAM students hosted by UFS this year to ten.

 

Building a climate-resilient future through agricultural education

The MAINSTREAM project aims to foster education and skills improvement in agricultural knowledge systems, with a strong focus on climate change resilience. According to Prof Witthuhn, the project “strives to influence the common agenda for addressing education and skills improvement … targeting transformations with the tertiary agricultural education community, policy, and industry actors”.

An important aspect of the initiative is its emphasis on inclusion, particularly regarding African women who remain underrepresented in higher education agricultural programmes. “Mobility schemes will also be used to break cross-African gendered perceptions of agriculture … and to further provide for a gender-sensitive learning environment and institutional culture,” Prof Witthuhn notes.

The UFS’ participation forms part of a larger network of partner institutions across Africa and Europe, including Arsi University (Ethiopia), the University of Kara (Togo), the Mountains of the Moon University (Uganda), Jaramogi Oginga Odinga University of Science and Technology (JOOUST, Kenya), the University of Sine Saloum El Hadji Ibrahima Niasse (USSEIN, Senegal), and the Weihenstephan-Triesdorf University of Applied Science (Germany).

 

Strengthening research, networks, and collaboration at the UFS

This four-year project, running from 2024 to 2027, will host two cohorts of students. “We are a partner in the project that will run over four years … one of the UFS master’s students, Rinus Behrens from the Department of Sustainable Food Systems and Development, is currently spending four months at JOOUST in Kenya as part of the programme,” adds Prof Witthuhn.

The presence of these students at the UFS marks a pivotal moment for both the institution and its international counterparts. “For the institution, it creates the opportunity for new networks, new research opportunities, internationalisation of our research endeavour, and increased research outputs,” she says.

During their stay, master’s and doctoral students will engage in academic research aligned with their fields of study, while traineeship students will gain hands-on agricultural experience on farms in the Bloemfontein area.

Bedada says the programme is already making a meaningful impact on his academic journey. “I am analysing the impact of agricultural mechanisation on food security and production. It is a big opportunity, because it gives me a chance to expand my knowledge and skills, and to develop my research work to international level.”

Similarly, Houngo says the experience so far has been enriching. “I have already learned a lot, and I hope to replicate the experience in my hometown,” he shares.

Behind the scenes, UFS staff and departments are instrumental in ensuring the programme’s success. “They provide host departments, academic leadership, and supervision to the six students,” says Prof Witthuhn, emphasising the collaborative effort required to support this international initiative.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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