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18 August 2025 | Story Somila Nazo | Photo Supplied
Prof Martin Nyaga
Prof Martin Nyaga delivered a keynote on Africa’s scientific leadership in genomics and global health at the African Academy of Sciences Summit in Accra, Ghana.

Prof Martin Nyaga, one of Africa’s foremost experts in genomics and global health, recently delivered a powerful call for Africa’s leadership in global science at the African Academy of Sciences (AAS) Summit in Accra, Ghana. 

As Head of the Next Generation Sequencing (NGS) Unit at the University of the Free State (UFS) and Director of the WHO Collaborating Centre for Vaccine Preventable Diseases Surveillance and Pathogen Genomics, Prof Nyaga urged the scientific community to recognise Africa not just as a participant in global research, but as a driver of innovation and change. 

 

A summit of vision and collaboration 

Themed Unpacking the Pact for the Future: Imperatives for Advancing Scientific Cooperation with Africa, the summit took place from 2 – 4 July 2025. Hosted by the AAS in partnership with the African Union, the Government of Ghana, the University of Ghana, and other global partners, the summit brought together leading scientists, policymakers, and international stakeholders to discuss Africa’s role in shaping the future of global science, research and innovation. 

The event was attended by high-level dignitaries, including the President of Ghana, His Excellency John Dramani Mahama, and the former President of Nigeria, His Excellency Olusegun Obasanjo – a clear indication of strong political will to prioritise science, health and innovation across the continent. 

 

Advancing Africa’s voice in global health 

On 2 July 2025, Prof Nyaga delivered his keynote address, Advances, Opportunities and Priorities for Global Health in Africa. He highlighted Africa’s growing capabilities in genomics and public health, underscoring the opportunities for scientific leadership. 

Following his address, he joined an expert panel with representatives from Tanzania, Ghana and Nigeria to discuss strategies for advancing scientific cooperation in global health. His contributions focused on: strengthening research collaborations; building capacity within Africa; increasing African ownership in health innovations, and enhancing the translation of research into policy and practice. 

Prof Nyaga also used the platform to spotlight the work of the UFS Next Generation Sequencing (UFS-NGS) Unit. As a WHO Collaborating Centre, the unit plays a critical role in pathogen tracking, monitoring vaccine-preventable diseases, and supporting public health preparedness across Africa and beyond. 

 “This engagement provided an opportunity to highlight the impactful research from the UFS-NGS Unit – not only in academic publications, but in demonstrating tangible public health benefits to policy makers,” said Prof Nyaga.  “It elevated the University of the Free State’s standing as a leader in genomic science, while opening new opportunities for collaboration for South Africa and the continent. Our research priorities are increasingly shaping global health and innovation agendas.” 

 

From Ghana to the G20 

The outcomes of the summit will feed into a communiqué to be presented at the 2025 G20 Summit, to be hosted by South Africa. Prof Nyaga’s thought leadership ensures that Africa’s scientific voice - and South Africa’s research priorities - will be represented at one of the world’s most influential multilateral platforms. 

For more information about UFS partnerships in Africa, contact the Office for International Affairs at partnerships@ufs.ac.za.  

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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