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18 August 2025 | Story Somila Nazo | Photo Supplied
Prof Martin Nyaga
Prof Martin Nyaga delivered a keynote on Africa’s scientific leadership in genomics and global health at the African Academy of Sciences Summit in Accra, Ghana.

Prof Martin Nyaga, one of Africa’s foremost experts in genomics and global health, recently delivered a powerful call for Africa’s leadership in global science at the African Academy of Sciences (AAS) Summit in Accra, Ghana. 

As Head of the Next Generation Sequencing (NGS) Unit at the University of the Free State (UFS) and Director of the WHO Collaborating Centre for Vaccine Preventable Diseases Surveillance and Pathogen Genomics, Prof Nyaga urged the scientific community to recognise Africa not just as a participant in global research, but as a driver of innovation and change. 

 

A summit of vision and collaboration 

Themed Unpacking the Pact for the Future: Imperatives for Advancing Scientific Cooperation with Africa, the summit took place from 2 – 4 July 2025. Hosted by the AAS in partnership with the African Union, the Government of Ghana, the University of Ghana, and other global partners, the summit brought together leading scientists, policymakers, and international stakeholders to discuss Africa’s role in shaping the future of global science, research and innovation. 

The event was attended by high-level dignitaries, including the President of Ghana, His Excellency John Dramani Mahama, and the former President of Nigeria, His Excellency Olusegun Obasanjo – a clear indication of strong political will to prioritise science, health and innovation across the continent. 

 

Advancing Africa’s voice in global health 

On 2 July 2025, Prof Nyaga delivered his keynote address, Advances, Opportunities and Priorities for Global Health in Africa. He highlighted Africa’s growing capabilities in genomics and public health, underscoring the opportunities for scientific leadership. 

Following his address, he joined an expert panel with representatives from Tanzania, Ghana and Nigeria to discuss strategies for advancing scientific cooperation in global health. His contributions focused on: strengthening research collaborations; building capacity within Africa; increasing African ownership in health innovations, and enhancing the translation of research into policy and practice. 

Prof Nyaga also used the platform to spotlight the work of the UFS Next Generation Sequencing (UFS-NGS) Unit. As a WHO Collaborating Centre, the unit plays a critical role in pathogen tracking, monitoring vaccine-preventable diseases, and supporting public health preparedness across Africa and beyond. 

 “This engagement provided an opportunity to highlight the impactful research from the UFS-NGS Unit – not only in academic publications, but in demonstrating tangible public health benefits to policy makers,” said Prof Nyaga.  “It elevated the University of the Free State’s standing as a leader in genomic science, while opening new opportunities for collaboration for South Africa and the continent. Our research priorities are increasingly shaping global health and innovation agendas.” 

 

From Ghana to the G20 

The outcomes of the summit will feed into a communiqué to be presented at the 2025 G20 Summit, to be hosted by South Africa. Prof Nyaga’s thought leadership ensures that Africa’s scientific voice - and South Africa’s research priorities - will be represented at one of the world’s most influential multilateral platforms. 

For more information about UFS partnerships in Africa, contact the Office for International Affairs at partnerships@ufs.ac.za.  

News Archive

Heart diseases a time bomb in Africa, says UFS expert
2010-05-17

 Prof. Francis Smit

There are a lot of cardiac problems in Africa. Sub-Saharan Africa is home to the largest population of rheumatic heart disease patients in the world and therefore hosts the largest rheumatic heart valve population in the world. They are more than one million, compared to 33 000 in the whole of the industrialised world, says Prof. Francis Smit, Head of the Department of Cardiothoracic Surgery at the Faculty of Health Sciences at the University of the Free State (UFS).

He delivered an inaugural lecture on the topic Cardiothoracic Surgery: Complex simplicity, or simple complexity?

“We are also sitting on a time bomb of ischemic heart disease with the WHO (World Health Organisation) estimating that CAD (coronary artery disease) will become the number-one killer in our region by 2020. HIV/Aids is expected to go down to number 7.”

Very little is done about it. There is neither a clear nor coordinated programme to address this expected epidemic and CAD is regarded as an expensive disease, confined to Caucasians in the industrialised world. “We are ignoring alarming statistics about incidences of adult obesity, diabetes and endemic hypertension in our black population and a rising incidence of coronary artery interventions and incidents in our indigenous population,” Prof. Smit says.

Outside South Africa – with 44 units – very few units (about seven) perform low volumes of basic cardiac surgery. The South African units at all academic institutions are under severe threat and about 70% of cardiac procedures are performed in the private sector.

He says the main challenge in Africa has become sustainability, which needs to be addressed through education. Cardiothoracic surgery must become part of everyday surgery in Africa through alternative education programmes. That will make this specialty relevant at all levels of healthcare and it must be involved in resource allocation to medicine in general and cardiothoracic surgery specifically.

The African surgeon should make the maximum impact at the lowest possible cost to as many people in a society as possible. “Our training in fields like intensive care and insight into pulmonology, gastroenterology and cardiology give us the possibility of expanding our roles in African medicine. We must also remember that we are trained physicians as well.

“Should people die or suffer tremendously while we can train a group of surgical specialists or retraining general surgeons to expand our impact on cardiothoracic disease in Africa using available technology maybe more creatively? We have made great progress in establishing an African School for Cardiothoracic Surgery.”

Prof. Smit also highlighted the role of the annual Hannes Meyer National Registrar Symposium that culminated in having an eight-strong international panel sponsored by the ICC of EACTS to present a scientific course as well as advanced surgical techniques in conjunction with the Hannes Meyer Symposium in 2010.

Prof. Smit says South Africa is fast becoming the driving force in cardiothoracic surgery in Africa. South Africa is the only country that has the knowledge, technology and skills base to act as the springboard for the development of cardiothoracic surgery in Africa.

South Africa, however, is experiencing its own problems. Mortality has doubled in the years from 1997 to 2005 and half the population in the Free State dies between 40 to 44 years of age.

“If we do not need health professionals to determine the quality and quantity of service delivery to the population and do not want to involve them in this process, we can get rid of them, but then the political leaders making that decision must accept responsibility for the clinical outcomes and life expectancies of their fellow citizens.

“We surely cannot expect to impose the same medical legal principles on professionals working in unsafe hospitals and who have complained and made authorities aware of these conditions than upon those working in functional institutions. Either fixes the institutions or indemnifies medical personnel working in these conditions and defends the decision publicly.

“Why do I have to choose the three out of four patients that cannot have a lifesaving operation and will have to die on their own while the system pretends to deliver treatment to all?”

Prof. Smit says developing a service package with guidelines in the public domain will go a long way towards addressing this issue. It is also about time that we have to admit that things are simply not the same. Standards are deteriorating and training outcomes are or will be affected.

The people who make decisions that affect healthcare service delivery and outcomes, the quality of training platforms and research, in a word, the future of South African medicine, firstly need rules and boundaries. He also suggested that maybe the government should develop health policy in the public domain and then outsource healthcare delivery to people who can actually deliver including thousands of experts employed but ignored by the State at present.

“It is time that we all have to accept our responsibilities at all levels… and act decisively on matters that will determine the quality and quantity of medical care for this and future generations in South Africa and Africa. Time is running out,” Prof. Smit says.
 

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