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18 August 2025 | Story Somila Nazo | Photo Supplied
Prof Martin Nyaga
Prof Martin Nyaga delivered a keynote on Africa’s scientific leadership in genomics and global health at the African Academy of Sciences Summit in Accra, Ghana.

Prof Martin Nyaga, one of Africa’s foremost experts in genomics and global health, recently delivered a powerful call for Africa’s leadership in global science at the African Academy of Sciences (AAS) Summit in Accra, Ghana. 

As Head of the Next Generation Sequencing (NGS) Unit at the University of the Free State (UFS) and Director of the WHO Collaborating Centre for Vaccine Preventable Diseases Surveillance and Pathogen Genomics, Prof Nyaga urged the scientific community to recognise Africa not just as a participant in global research, but as a driver of innovation and change. 

 

A summit of vision and collaboration 

Themed Unpacking the Pact for the Future: Imperatives for Advancing Scientific Cooperation with Africa, the summit took place from 2 – 4 July 2025. Hosted by the AAS in partnership with the African Union, the Government of Ghana, the University of Ghana, and other global partners, the summit brought together leading scientists, policymakers, and international stakeholders to discuss Africa’s role in shaping the future of global science, research and innovation. 

The event was attended by high-level dignitaries, including the President of Ghana, His Excellency John Dramani Mahama, and the former President of Nigeria, His Excellency Olusegun Obasanjo – a clear indication of strong political will to prioritise science, health and innovation across the continent. 

 

Advancing Africa’s voice in global health 

On 2 July 2025, Prof Nyaga delivered his keynote address, Advances, Opportunities and Priorities for Global Health in Africa. He highlighted Africa’s growing capabilities in genomics and public health, underscoring the opportunities for scientific leadership. 

Following his address, he joined an expert panel with representatives from Tanzania, Ghana and Nigeria to discuss strategies for advancing scientific cooperation in global health. His contributions focused on: strengthening research collaborations; building capacity within Africa; increasing African ownership in health innovations, and enhancing the translation of research into policy and practice. 

Prof Nyaga also used the platform to spotlight the work of the UFS Next Generation Sequencing (UFS-NGS) Unit. As a WHO Collaborating Centre, the unit plays a critical role in pathogen tracking, monitoring vaccine-preventable diseases, and supporting public health preparedness across Africa and beyond. 

 “This engagement provided an opportunity to highlight the impactful research from the UFS-NGS Unit – not only in academic publications, but in demonstrating tangible public health benefits to policy makers,” said Prof Nyaga.  “It elevated the University of the Free State’s standing as a leader in genomic science, while opening new opportunities for collaboration for South Africa and the continent. Our research priorities are increasingly shaping global health and innovation agendas.” 

 

From Ghana to the G20 

The outcomes of the summit will feed into a communiqué to be presented at the 2025 G20 Summit, to be hosted by South Africa. Prof Nyaga’s thought leadership ensures that Africa’s scientific voice - and South Africa’s research priorities - will be represented at one of the world’s most influential multilateral platforms. 

For more information about UFS partnerships in Africa, contact the Office for International Affairs at partnerships@ufs.ac.za.  

News Archive

Dr Charlotte Boucher and Lindi Heyns examine possible anti-microbial activity in the skin of Western olive toad species
2014-12-22

 

Researchers Lindi Heyns and Dr Charlotte Boucher are working together on an interdisciplinary project between the Departments of Zoology and Entomology and Veterinary Biotechnology at the University of the Free State (UFS). The focus of their research is on the preliminary biochemical description of skin secretions in some South African toads.

The project forms part of an Honours study executed by Dwayne Pike under Heyns’ supervision. He is co-supervised by Dr Boucher who is assisting with the biochemical and microbiological assays.

Dr Boucher said, “Amphibians are characterised by the presence of cutaneous glands spread over the skin. There are two types of glands, namely mucous and granular (poison), located on the inner surface of the epidermis. Mucous glands are widely dispersed over the skin, while granular glands can be grouped and enlarged in specific regions. Mucous glands are generally associated with maintenance of humidity and cutaneous respiration, whereas granular glands function in chemical defence against predators and/or microbial infection. Studies indicate that the compounds produced by the granular glands belong to numerous chemical classes with diverse pharmacological activities.”

The products secreted by granular glands are rich in low molecular weight constituents of varied molecular types, including proteins, peptides and toxins. These secretions make the toad foul-tasting to predators and even toxic to other frog species. In addition, amphibians offer an attractive source of novel antimicrobials. Studies indicate that as a response to inhabiting microorganism-rich environments they synthesise and secrete a diverse array of antimicrobial peptides (AMPs) as an innate form of defence. Extensive research by various other research groups has been carried out on antimicrobial peptides of the genus Rana; however, hardly any studies have investigated the antimicrobial activity of African frog species.

The focus of this preliminary project is to determine the protein composition of the glandular secretions of the Western olive toad (Amietophrynus poweri), using biochemical tests, such as SDS-PAGE also known as protein gel electrophoresis combined with mass-spectrometry used to identify unknown peptides and proteins. This will give us an overview of the composition of the glandular secretions. Furthermore, we are also looking at microbiological tests, which include assays that test for possible anti-microbial activity against various bacterial and fungal species.

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