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21 August 2025 | Story Tshepo Tsotetsi | Photo Tshepo Tsotetsi
EMS Womens Function
From the left: Prof Brownhilder Neneh, Vice-Dean of the Faculty of Economic and Management Sciences; Prof Hester C. Klopper, Vice-Chancellor and Principal of the UFS; Simone Williams, Faculty Manager; and Dr Celeste Campher, Senior Lecturer in the Faculty of Economic and Management Sciences, at the Women’s Function held on the Bloemfontein Campus on 18 August.

The University of the Free State’s (UFS) Faculty of Economic and Management Sciences recently hosted a Women’s Function on the UFS Bloemfontein Campus – an event that paid tribute to women’s leadership in academia during Women’s Month. The gathering, held on 18 August 2025, was marked by a historic conversation with Prof Hester C. Klopper, UFS Vice-Chancellor and Principal, who earlier this year became the first woman to lead the university in its 121-year history.

The function brought together women academics and professional staff in an atmosphere of connection and reflection to converse on breaking barriers, building futures, and empowering women in higher education. In conversation with colleagues, Prof Klopper shared her personal journey in higher education, her leadership philosophy, and the values that have guided her career. The occasion created a meaningful platform for colleagues to reflect on the role of women in shaping the future of the faculty and the university.

 

Breaking barriers, building futures

Prof Klopper described her appointment as both humbling and historic: “It is an extraordinary honour to be entrusted with this responsibility. This milestone is not just a personal achievement, but also a reflection of the progress we have made as a university and as a society in recognising and valuing diversity in leadership. I stand on the shoulders of many trailblazers who paved the way, and I hope my appointment inspires women to believe that there are no limits to what they can achieve.”

She shared pivotal moments across her career journey – from transitioning into academia to international leadership experiences that shaped her vision. “You become aware of a growing, burning desire to plough back what you have learned; to pay forward in some way after receiving so many opportunities for growth, so much exposure to great role models, and such incredible learning experiences,” she said.

Acknowledging the challenges women still face in higher education, Prof Klopper reflected: “Academia has traditionally been male-dominated. In order to overcome stereotyping and bias, I drew on the values instilled by my parents – hard work, believing in yourself, non-discrimination, fairness, and care. These have been incredibly valuable in my journey.” She also highlighted the importance of supportive partnerships when balancing professional and family responsibilities.

Prof Brownhilder Neneh, Vice-Dean: Research, Engagement and Internationalisation in the Faculty, said these reflections captured the very purpose of the gathering. “With Prof Klopper serving as the first female Vice-Chancellor and Principal of the UFS, it was important to create a platform for her to inspire and empower women academics,” she said. “By sharing her career journey and insights, she demonstrated how barriers can be overcome in higher education leadership.” 

She added that the conversation reinforced an important message: “Women, too, can achieve whatever they aspire to become. Prof Klopper reminded us that one must be clear about the message they want to communicate, know what they stand for, and remain consistent, authentic and honest. She emphasised the importance of always considering what you bring to the table – your expertise and knowledge – which ultimately opens doors. She also reminded us that women need to create their own values and live them, be intentional, and show up. There is no single recipe – each person must find their own rhythm and pursue it deliberately.”

Prof Klopper echoed with a message of encouragement to young women: “Have the courage to embrace your own authentic leadership style. Do not allow others to define who you are – believe in your own abilities. Knowledge without action is incomplete. Lead with heart, take intellectual risks, and remember that talent exists everywhere, but you have the power to create opportunity.”

Prof Neneh added that the event was not only a celebration but also a call to action: “Women play a vital role in enriching the academic project by bringing diverse experiences, perspectives, and leadership approaches. I hope colleagues left encouraged to pursue their aspirations with confidence and inspired to embrace mentorship, sponsorship, and solidarity among women academics.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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