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19 February 2025 | Story Leonie Bolleurs | Photo Supplied
Prof Hagenmeier and Prof Jacobs
Prof Lynette Jacobs and Dr Cornelius Hagenmeier, one of her hosts at the Mittweida University of Applied Sciences (HSMW). Prof Jacobs, a visiting professor at this institution, had the opportunity to visit the HSMW on a guest scholarship grant from the State of Saxony.

Since its foundation in 1867, Mittweida University of Applied Sciences (HSMW) has had internationality as a trademark. In its early decades, more than half of its students came from abroad to study at this institution in Saxony, Germany. Today, the university is working with more than 100 partners worldwide, including the University of the Free State (UFS).

In September last year, the UFS signed a memorandum of understanding (MOU), outlining the intention to collaborate on the exchange of academic staff and researchers for teaching, lectures, and research, as well as for the sharing of expertise. Additionally, the institutions are also looking at student exchange opportunities, conducting joint research projects, hosting symposia, seminars, and conferences together, and exchanging academic information and materials.

Internationalisation as a cross-cutting process

Recently, Prof Lynette Jacobs, the interim Director of the Office for International Affairs at the UFS, visited the institution as a visiting professor at the HSMW, after receiving a guest professorship grant from the Free State of Saxony in Germany.

This opportunity not only provided her with the chance to gain insight into the HSMW and build an understanding of the possibilities for collaboration between the two institutions but also allowed her to directly contribute to their strategy development. She worked on a research project with her hosts, Prof Ramona Kusche, Dean of Studies, Global Communications in Business and Culture, and Dr Cornelius Hagenmeier, Head of Internationalisation. “We responded to the question of the extent to which the HSMW has achieved the goals of its 2018 internationalisation strategy,” she says.

In this study, they found that the HSMW is known for its attractive study programmes, forward-thinking content, interactive approaches, and its innovativeness and agility. This is reflected in the views of staff and students who participated in the interviews and the survey. It also became clear that the HSMW’s internationalisation strategy intentionally draws on the character and strengths of the university, which has enabling structures and appropriate governance frameworks for internationalisation. She says this research provided her with an opportunity to reflect on the UFS’ institutional strategic plans for internationalisation and how to strengthen the strategy and its implementation.

Internationalisation strategies in a different context

“The engagement with the HSMW provided me with an important additional perspective for the internationalisation strategy revision process at the UFS,” she states, adding that spending time at the HSMW gave her a unique understanding of the development and implementation of internationalisation strategies in a different context.

Besides reviewing the HSMW’s 2018 internationalisation strategy, Prof Jacobs has also collaborated on other research projects. She co-authored both a Routledge book chapter and a manuscript of a scientific article by Prof Kusche, Dr Hagenmeier, and others. As a result of the contacts she made during her visiting professorship, she is also now involved in the guest-editing of a special issue of the journal Internationalisation of Higher Education – Policy and Practice with the theme Institutional Internationalisation Strategies in a Rapidly Changing Global Environment.

Prof Jacobs delivered a number of guest lectures during her stay in Saxony, for instance, ‘Different ways of knowing, being and relating’ (to master’s students) and ‘South African culture, Ubuntu and Pan-Africanism’ (to undergraduate students).  She furthermore engaged in various dialogue sessions and workshops with lecturers and researchers at the HSMW, focusing on the integration of international and intercultural dimensions in curricula or in their research. She participated in discussions with some young female academics on science and career development and contributed to an international workshop on Institutional Internationalisation Strategies in a Rapidly Changing Global Environment, where initial research findings were presented that will inform the strategy's upcoming revision.

The young but growing partnership between the UFS and the HSMW promises benefits for both institutions. Two complementary face-to-face internationalisation colloquium sessions are scheduled for 2025:  the first during the HSMW International Week in June, and the second on the UFS Bloemfontein Campus in September.  This will further deepen the collaboration, building a shared understanding of integrated internationalisation, contributing to scholarship of internationalisation, and enriching the academic and cultural exchange between the universities. Collaboration in terms of mentorship programmes between the two universities is on the cards, while specific departments at the UFS (e.g. the Department of Social Work and the Department of Facilities) have already started their collaboration in 2024.

For more information about partnerships, contact the Office for International Affairs at partnerships@ufs.ac.za.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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