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19 February 2025 | Story Leonie Bolleurs | Photo Supplied
Prof Hagenmeier and Prof Jacobs
Prof Lynette Jacobs and Dr Cornelius Hagenmeier, one of her hosts at the Mittweida University of Applied Sciences (HSMW). Prof Jacobs, a visiting professor at this institution, had the opportunity to visit the HSMW on a guest scholarship grant from the State of Saxony.

Since its foundation in 1867, Mittweida University of Applied Sciences (HSMW) has had internationality as a trademark. In its early decades, more than half of its students came from abroad to study at this institution in Saxony, Germany. Today, the university is working with more than 100 partners worldwide, including the University of the Free State (UFS).

In September last year, the UFS signed a memorandum of understanding (MOU), outlining the intention to collaborate on the exchange of academic staff and researchers for teaching, lectures, and research, as well as for the sharing of expertise. Additionally, the institutions are also looking at student exchange opportunities, conducting joint research projects, hosting symposia, seminars, and conferences together, and exchanging academic information and materials.

Internationalisation as a cross-cutting process

Recently, Prof Lynette Jacobs, the interim Director of the Office for International Affairs at the UFS, visited the institution as a visiting professor at the HSMW, after receiving a guest professorship grant from the Free State of Saxony in Germany.

This opportunity not only provided her with the chance to gain insight into the HSMW and build an understanding of the possibilities for collaboration between the two institutions but also allowed her to directly contribute to their strategy development. She worked on a research project with her hosts, Prof Ramona Kusche, Dean of Studies, Global Communications in Business and Culture, and Dr Cornelius Hagenmeier, Head of Internationalisation. “We responded to the question of the extent to which the HSMW has achieved the goals of its 2018 internationalisation strategy,” she says.

In this study, they found that the HSMW is known for its attractive study programmes, forward-thinking content, interactive approaches, and its innovativeness and agility. This is reflected in the views of staff and students who participated in the interviews and the survey. It also became clear that the HSMW’s internationalisation strategy intentionally draws on the character and strengths of the university, which has enabling structures and appropriate governance frameworks for internationalisation. She says this research provided her with an opportunity to reflect on the UFS’ institutional strategic plans for internationalisation and how to strengthen the strategy and its implementation.

Internationalisation strategies in a different context

“The engagement with the HSMW provided me with an important additional perspective for the internationalisation strategy revision process at the UFS,” she states, adding that spending time at the HSMW gave her a unique understanding of the development and implementation of internationalisation strategies in a different context.

Besides reviewing the HSMW’s 2018 internationalisation strategy, Prof Jacobs has also collaborated on other research projects. She co-authored both a Routledge book chapter and a manuscript of a scientific article by Prof Kusche, Dr Hagenmeier, and others. As a result of the contacts she made during her visiting professorship, she is also now involved in the guest-editing of a special issue of the journal Internationalisation of Higher Education – Policy and Practice with the theme Institutional Internationalisation Strategies in a Rapidly Changing Global Environment.

Prof Jacobs delivered a number of guest lectures during her stay in Saxony, for instance, ‘Different ways of knowing, being and relating’ (to master’s students) and ‘South African culture, Ubuntu and Pan-Africanism’ (to undergraduate students).  She furthermore engaged in various dialogue sessions and workshops with lecturers and researchers at the HSMW, focusing on the integration of international and intercultural dimensions in curricula or in their research. She participated in discussions with some young female academics on science and career development and contributed to an international workshop on Institutional Internationalisation Strategies in a Rapidly Changing Global Environment, where initial research findings were presented that will inform the strategy's upcoming revision.

The young but growing partnership between the UFS and the HSMW promises benefits for both institutions. Two complementary face-to-face internationalisation colloquium sessions are scheduled for 2025:  the first during the HSMW International Week in June, and the second on the UFS Bloemfontein Campus in September.  This will further deepen the collaboration, building a shared understanding of integrated internationalisation, contributing to scholarship of internationalisation, and enriching the academic and cultural exchange between the universities. Collaboration in terms of mentorship programmes between the two universities is on the cards, while specific departments at the UFS (e.g. the Department of Social Work and the Department of Facilities) have already started their collaboration in 2024.

For more information about partnerships, contact the Office for International Affairs at partnerships@ufs.ac.za.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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