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25 February 2025 | Story Anthony Mthembu | Photo Kaleidoscope Studios
G20 - 2025
G20 delegates from member countries and other invited guests in attendance at the G20 Research and Innovation Working Group (RIWG) and G20 Initiative on Bioeconomy (GIB) meetings and other side events.

Against the backdrop of the upcoming G20 Summit to be hosted by South Africa in November 2025, the University of the Free State (UFS) – in partnership with the Department of Science, Technology and Innovation (DSTI) – held the G20 Research and Innovation Working Group (RIWG) and G20 Initiative on Bioeconomy (GIB) meetings on 23 and 24 February 2025.

In her opening address to G20 delegates from member countries, national and international knowledge partners, members of the Free State provincial government, and representatives of the DSTI, Prof Hester Klopper, Vice-Chancellor and Principal of the UFS, indicated, “It is an honour for the UFS to be among the few South African universities to host this essential Research and Innovation Working Group.” In addition, she highlighted that the deliberations and discussions set to take place during this important workshop can set in motion chains of events ultimately contributing to improved lives for everyone. These sentiments were also echoed by Prof Blade Nzimande, Minister of Science, Technology and Innovation, who underscored the importance and historic nature of the upcoming G20 Summit.

In his virtual address, Minister Nzimande explained that South Africa’s chosen theme for the G20 Summit – Solidarity, Equality and Sustainability – was inspired by the general complexity of our time, “in particular the transnational nature of these complexities, such as conflict, the displacement of people, poverty”, among other things. As such, he expressed that in this case, cooperation among nations is becoming increasingly essential.

As they concluded their addresses, Prof Nzimande and Prof Klopper, wished the delegates well in their deliberations. ‘’May your discussions be successful, and your goals be achieved. And may your time with us lead to a renewed experience of the value of innovation through connection, ‘’expressed Prof Klopper.

 

Contributing events

As part of the programme at these proceedings, several side events took place. These included panel discussions with indigenous knowledge holders such as Telle Hoeses, Chief Language Practitioner for Khoi and San Languages, along with experts of indigenous medicine. The conversation focused on indigenous knowledge systems (IKS) and some of the key concerns and progress that these knowledge holders have made in the space. In addition, these knowledge holders, many of whom are business owners who sell products made from indigenous medicines, also had the opportunity to exhibit their products. According to Dan du Toit, Deputy Director-General: International Cooperation and Resources at the DSTI, these panel discussions with young people, bioeconomy researchers, and indigenous knowledge holders were an opportunity to gain access to a diversity of voices, which would not normally find expression in formal meetings. “It is also an opportunity for our international guests to get insight into who we are as a country and what some of our concerns might be,” said Du Toit.

One of the highly anticipated side events on the programme was the joint G20 RIWG and GIB event titled ‘UNESCO Women and Girls in Science’, which took place on 25 February 2025. The event took the form of a round-table discussion, in an attempt to answer the question: Based on your experiences in various roles within higher education in South Africa, Africa, and globally, what are some key insights regarding the role of universities in closing the gender gap in STEM, specifically concerning professional development and creating supportive research environments where everyone, especially women, can thrive?

Prof Anthea Rhoda; Deputy Vice-Chancellor: Academic at the UFS, was one of the contributors in this session. In response to the question, Prof Rhoda highlighted, “Universities should also be spaces characterised by intellectual freedom and freedom of expression, where archaic ideas about male superiority and patriarchy can be openly confronted and contested, without fear of victimisation. She expressed that an active way in which the UFS has committed itself to a culture of diversity and inclusion is through Vision130.

As she was wrapping up her address, Prof Rhoda also highlighted, “To address areas of underrepresentation of women in senior academic and leadership positions within the university, a Working Group on Gender Parity in Academic Leadership was established, with the critical mandate to drive attitudinal shifts, advocate for changes where necessary, and highlight barriers to women’s advancement.”

 

The programme comes to an end

The last day of the programme was reserved for comments, reflections, and discussions on deliverables. As such, there were positive responses to the way the deliberations took place. In fact, Hoese, speaking in her capacity as an indigenous knowledge holder, said, “This was a good platform for us to make progress towards language recognition and officialisation.”

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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