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23 February 2025 | Story André Damons | Photo Supplied
UFS Main Building
The University of the Free State in partnership with the Department of Science, Technology and Innovation (DSTI), will form the backdrop for the G20 Research and Innovation Working Group (RIWG) and G20 Initiative on Biochemistry (GIB) meetings in February.

The University of the Free State (UFS) will form the backdrop for the G20 Research and Innovation Working Group (RIWG) and G20 Initiative on Bioeconomy (GIB) meetings on 23 and 24 February 2024.

UFS has, over the years, distinguished itself as a leader in the research and development, particularly in the biodiversity space through its African Medicines, Innovations and Technologies Development (AMITD) platform, which was established in collaboration with the Department of Science, Technology and Innovation (DSTI) and its entity, the Technology Innovation Agency.  It was therefore an obvious choice for the institution to again partner with the DSTI to host the G20 meetings.

The G20 is an international forum comprising many of the world's largest developing and developed economies, established to tackle pressing global economic and financial issues.

South Africa holds the G20 Presidency this year – only five years before the UN's 2030 Agenda for Sustainable Development deadline.  This is the first time the G20 is being hosted on African soil.

South Africa's presidency takes place when the world is facing a series of overlapping and mutually reinforcing crises, including climate change, underdevelopment, inequality, poverty, hunger, unemployment, technological changes, and geopolitical instability.

The G20 RIWG provides a platform for addressing global challenges through research, technology and innovation.  The DSTI will lead the RIWG under the leadership of Minister Blade Nzimande and explore this year's theme, "Equity in science and innovation-based approaches to sustainable development".

Prof Nzimande, along with Prof Hester Klopper, Vice-Chancellor and Principal of UFS, will both deliver opening remarks at the meeting.

The session on 23 February will be the first to include G20 officials engaging with indigenous knowledge holders, students and researchers in the bioeconomy.

Prof Motlalepula Matsabisa, Director of the Department of Pharmacology and AMITD at UFS, says the university was an excellent choice to host the sessions because of its trusted relationships with indigenous communities and focus on inclusive research and development.

The G20 dialogues aim to be inclusive and provide a space for members of the public to voice their aspirations and to capture their needs around the indigenous knowledge and biodiversity in which they play an integral role.

"I am honoured to be part of this global event.  I am so happy that AMITD is now globally recognised.  We will exhibit our research conducted with communities on the internationalisation of South African science research in traditional medicines and biodiversity, and its formal commercialisation," said Prof Matsabisa.

"We are the leader in traditional medicines research and development.

"South Africa always leads in global debates and sets the stage for African views to be heard.  We will contribute to policies on global biodiversity and bioeconomy and commercialisation of our natural resources through equity, sustainability and solidarity.

Prof Matsabisa believes this event will also highlight the goals of the DSTI's 2019 White Paper on Science, Technology and Innovation and the implementation of its 2022-2032 Decadal Plan.

He hopes to see tangible and meaningful outcomes from the G20 discussions that will be implemented by the USA when it takes over the G20 Presidency for 2026.

News Archive

Collaboration between UFS and Mayo Clinic to revolutionise cancer treatment
2014-06-27



Attending the lecture were, from the left: Dr Chantel Swart, Prof Lodewyk Kock, Prof Debabrata Mukhopadhyay, Prof James du Preez; back: Prof Pieter van Wyk.
Dr Swart, Profs Kock and Du Preez are from the Department of Microbial, Biochemical and Food Biotechnology. Prof Mukhopadhyay is from the Mayo Clinic (US) and Prof Van Wyk is from the Centre for Microscopy at the UFS.
Photo: Supplied
The UFS made a discovery that may have enormous implications for the treatment of diseases in humans.

Since the discovery, the UFS joined forces with the Mayo Clinic in Rochester, US, in the fight against cancer.

In this collective effort, UFS researchers would be able to assist the Mayo team to:
• see how treatment in cancer patients is progressing,
• target treatments more effectively,
• reduce dosages in order to make treatment gentler on the patient,
• track the effectiveness of the chemotherapy drugs used, and
• gain an accurate view of how the cancer is being eliminated.

Prof Lodewyk Kock, Outstanding Professor at the Department of Microbial, Biochemical and Food Biotechnology, and his team incidentally created a technique to use argon gas particles for the first time on biological material to slice open cells to look inside.

The team that supported Prof Kock includes Dr Chantel Swart, Khumisho Dithebe (PhD student), Prof Hendrik Swart (Department of Physics) and Prof Pieter van Wyk (Centre for Microscopy).

Prof Debabrata Mukhopadhyay from the Mayo Clinic in Rochester, US, got to hear about this breakthrough at the UFS and a collaboration between the two institutions was established.

During a visit to the Bloemfontein Campus, Prof Mukhopadhyay explained novel techniques that make use of gold nanoparticles. These particles attach to chemotherapeutic drugs to selectively target cancer cells – dramatically decreasing the side effects to normal human cells.

For these new drugs (coupled to gold nanoparticles) to be accepted into clinical practice, visual and chemical proof is needed, though. This is where the technique developed by the UFS will play a vital role.

With the technique to look inside cells, the composition, location and metabolism of these drugs can be determined. This will aid in a proof of concept for the application of the nano-drugs. Furthermore, it will enable approval for use of these drugs in clinical trials and eventually could revolutionise cancer treatment as a whole.

For video lectures on the technique used, as well as its findings, follow these links:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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