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06 January 2025 | Story Anthony Mthembu | Photo Supplied
Prof Solomon Werta
Prof Solomon Werta, UFS alumnus and Vice-President: Administration and Development at Dire Dawa University, continues to inspire as one of Ethiopia's youngest leaders in higher education.

Throughout the progression of his career, the UFS alumnus, Prof Solomon Werta – Vice-President: Administration and Development at the Dire Dawa University (DDU) – has been the ‘youngest’ to occupy positions of leadership in several instances. 

In fact, the DDU appointed Prof Werta as Vice-President: Research and Community Service in 2020, making him the youngest vice-president of any public university in Ethiopia. According to Prof Werta, when it comes to senior management roles in universities and government, the norm is that the positions are held by middle-aged, mature leaders. However, after a unanimous vote by senate members at the university, he assumed that role at the age of 31. “Holding such a senior position at that age makes me a role model not only for a generation of young people, but for those at the University of the Free State who may be following my career,” Prof Werta stated. 

What the role entailed 

As Vice-President: Research and Community Service, he was responsible for driving research, innovation, technology transfer, community engagement, and growth within the institution and the community at large. As such, some of his highlights within this role include establishing a university community radio station to serve both the university and the Dire Dawa community, establishing new university journals such as the Harla journal, and establishing a nationally accredited institutional review board, among others. 

He occupied this role until November 2023 when he was promoted to his current role as Vice-President: Administration and Development at the DDU. Prof Werta credits this most recent promotion to the dedication and hard work he put into his previous role, as well as the knowledge and experience he acquired during his time at the UFS. 

In recognition of his work as a researcher within the Department of Physics at the DDU, Prof Werta was also promoted to Associate Professor in Physics. As a result, he indicates that he can be regarded as the youngest associate professor of physics in Ethiopia. Therefore, he continues to contribute to his institution and beyond on these accounts. 

What the future holds 

Prof Werta indicated that he plans on continuing to make strides as his career progresses, particularly in his role as Vice-President: Administration and Development. “I’d like to focus on increasing the university’s internal revenue, particularly through urban farming and other businesses using our academics,” said Prof Werta. In addition, he would also like to work on changing the university’s internal business practices, particularly the automation and digitalisation of the university system and the implementation of a contemporary university property management system, among others. 

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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