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16 January 2025 | Story Dr Cindé Greyling | Photo Supplied
Green Futures Hub
Prof Wayne Truter, who is leading the Green Futures Hub at the UFS, highlights that mining and agriculture are important yet competing industries in South Africa. The hub aims to find sustainable ways for them to coexist.

Our earth is very resilient, and a green future is possible, but we must make changes. At the forefront of this mission is the Green Futures Hub, spearheaded by Prof Wayne Truter at the UFS. Prof Truter holds a PhD in Integrated Agricultural and Environmental Sciences, with more than 25 years of experience. He is a leader in the field of forage, pasture, and land regeneration – particularly those impacted by mining. 

The Green Futures Hub is a virtual platform that bridges academic research and industry gaps, aiming to solve real-world challenges with scientific insights. It is designed to showcase and integrate the research happening across various disciplines at the University of the Free State (UFS), making it accessible to industry and communities alike. “People often lose faith in academic institutions, thinking that the research done there has no practical value,” Prof Truter notes. “The Green Futures Hub aims to change that by making scientific findings accessible and relevant to daily life.” 

This platform offers a unique opportunity for industries to connect with researchers working on solutions related to climate change, sustainable agriculture, or environmental rehabilitation. “Our hub is a space where industries can come to us with their challenges, and we can offer solutions based on research,” Prof Truter explains. “It’s about creating real impact.” 

Collaboration and integration are central to the Green Futures Hub’s approach. “Through interdisciplinary collaboration and a commitment to environmental stewardship, we want to develop solutions to the complex development challenges related to ecosystems, agroecosystems, water resources, biodiversity, infrastructure, and communities,” says Prof Truter. 

One of the hub’s projects that is close to Prof Truter’s heart, is the future coexistence of mining and agriculture. Mining and agriculture are two important industries in South Africa, often competing for land. However, the hub seeks to bridge this gap by exploring how these industries can coexist sustainably.  

“The future coexistence of mining and agriculture is critical,” says Prof Truter. “While mining often uses the land intensively, they have the responsibility and capability to rehabilitate it for agricultural use, ensuring that it is as productive – if not more – than it was before. Farmers and miners have much to gain from each other,” he explains. “By partnering with industries, we can help rehabilitate the land that has been mined, and in turn, farmers can harness and bring back the productivity to that land with the financial inputs of mining companies.” 

Prof Truter also emphasises the importance of science communication. “We need to do better at communicating the value of the research we’re doing. Many times, industries don’t understand the significance of what we’re working on because it’s not explained in a way that resonates with them. The hub ensures that research findings are accessible, understandable, and applicable to real-world issues.”  

The Green Futures Hub is more than just a research platform; it is a testament to the power of collaboration between academia and industry. “We’re not just conducting research,” Prof Truter concludes, “we’re developing solutions.” 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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