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02 January 2025 | Story Gerda-Marie van Rooyen | Photo Supplied
Prof Linus Franke
Leading the research in South Africa is Prof Linus Franke from the Department of Soil, Crop and Climate Sciences.

Scientists are actively pursuing the successful breeding of diploid hybrid potatoes from inbred lines. This is expected to revolutionise potato breeding as it holds the key to rapid genetic progress. It will introduce new varieties for commercialisation through seed. Currently, existing potato variants have a gene that renders self-pollinated seeds infertile.

Prof Linus Franke, an academic in the Department of Soil, Crop and Climate Sciences at the UFS, is leading the research in South Africa. “This technology allows the production of genetically uniform potato seed that is easy to transport and largely disease-free.” He says this differs from conventional breeding whereby only vegetative propagation is possible due to tetraploid varieties in potatoes. It also risks carrying pests and diseases from one generation to the next – leading to the accumulation of pests and diseases with each round of multiplication.

Seed innovation

Prof Franke explains that Solynta BV, a seed company based in the Netherlands that produces potato varieties that can be grown from seed, has included South Africa in their research efforts because it is one of Africa’s largest producers and exporters. Through his academic relationship with Wageningen University and Research, a Dutch institution renowned for its agricultural endeavours and food production, the UFS became involved in researching hybrid potatoes grown from seed.

Diploid seeds containing two sets of chromosomes allow easier gene manipulation to increase predictability and speedier genetic progress. The breeding approach enables the incorporation of tolerance to pests, diseases, abiotic stresses (cold, heat, drought) and other desired genetic traits.

Although Prof Franke is optimistic about this research, he is not blind to disadvantages. “Potato seeds are tiny and have little energy reserves, making it harder to grow potatoes from seed than from tubers.” He says potatoes from seed will take longer to cultivate than tubers, as farmers need to grow plantlets from seeds first, adding six weeks to the growing period. “It is possible that commercial farmers can grow potatoes directly from seed. Alternatively, perhaps more likely, specialised growers will produce tubers of potatoes from seed; these tubers are then sold as seed tubers to other potato farmers, who then continue their normal practices of producing potatoes for the market from tubers.”

Financial benefits

Prof Franke says farmers have reason to get excited. “Seed potatoes will reduce input costs, as varieties with enhanced tolerance to pests and diseases require less pesticides. Planting one hectare of potatoes requires three to four tonnes of potato tubers, but only one 25 g packet of potato seeds.” Since potatoes are a more valuable commodity than maize, this technology might also increase farmers’ income potential.

News Archive

New research informs improved treatment of brain inflammation
2017-10-13

Description: Sebolai and Ogundeji Tags: Microbiologist, Dr Adepemi Ogundeji,  

Dr Adepemi Ogundeji, researcher in the Department of Microbial,
Biochemical and Food Biotechnology at the
University of the Free State,
and Dr Olihile Sebolai,
her study leader from the same department.
Photo: Charl Devenish



Microbiologist Dr Adepemi Ogundeji has uncovered a new use for an old medicine that can potentially save lives and money. Under the guidance of her study leader, Dr Olihile Sebolai, Dr Ogundeji set out to fight a fungal disease caused by Cryptococcus neoformans. Drs Ogundeji and Sebolai are from the University of the Free State Department of Microbial, Biochemical and Food Biotechnology. 

Dr Ogundeji is passionate about education. “My aim will always be to transfer knowledge and skills in the microbiology field,” she said. “Dr Ogundeji’s study is celebrated in that it found a new purpose for existing medicines. An advantage of repositioning old medicines is by-passing clinical trials, which sometimes take 20 years, and the safety of such medicines is already known,” Dr Sebolai, explained.

Cryptococcus infections are difficult to control and often lead to brain inflammation. In layman’s terms: “Your brain is on fire”. People with HIV/Aids are especially vulnerable, surviving only about three months without treatment. Such patients may present with a Cryptococcus-emergent psychosis, and some with an out-of-control inflammatory condition when initiated on ARVs. 

Dr Ogundeji found that the clinically recommended dosage of aspirin (anti-inflammatory medicine), and quetiapine (anti-psychotic medicine) is sufficient to control the infection. Her exceptional work was readily published in some of the foremost journals in her field, namely, Antimicrobial Agents and Chemotherapy and Frontiers in Microbiology

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