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02 January 2025 | Story Gerda-Marie van Rooyen | Photo Supplied
Prof Linus Franke
Leading the research in South Africa is Prof Linus Franke from the Department of Soil, Crop and Climate Sciences.

Scientists are actively pursuing the successful breeding of diploid hybrid potatoes from inbred lines. This is expected to revolutionise potato breeding as it holds the key to rapid genetic progress. It will introduce new varieties for commercialisation through seed. Currently, existing potato variants have a gene that renders self-pollinated seeds infertile.

Prof Linus Franke, an academic in the Department of Soil, Crop and Climate Sciences at the UFS, is leading the research in South Africa. “This technology allows the production of genetically uniform potato seed that is easy to transport and largely disease-free.” He says this differs from conventional breeding whereby only vegetative propagation is possible due to tetraploid varieties in potatoes. It also risks carrying pests and diseases from one generation to the next – leading to the accumulation of pests and diseases with each round of multiplication.

Seed innovation

Prof Franke explains that Solynta BV, a seed company based in the Netherlands that produces potato varieties that can be grown from seed, has included South Africa in their research efforts because it is one of Africa’s largest producers and exporters. Through his academic relationship with Wageningen University and Research, a Dutch institution renowned for its agricultural endeavours and food production, the UFS became involved in researching hybrid potatoes grown from seed.

Diploid seeds containing two sets of chromosomes allow easier gene manipulation to increase predictability and speedier genetic progress. The breeding approach enables the incorporation of tolerance to pests, diseases, abiotic stresses (cold, heat, drought) and other desired genetic traits.

Although Prof Franke is optimistic about this research, he is not blind to disadvantages. “Potato seeds are tiny and have little energy reserves, making it harder to grow potatoes from seed than from tubers.” He says potatoes from seed will take longer to cultivate than tubers, as farmers need to grow plantlets from seeds first, adding six weeks to the growing period. “It is possible that commercial farmers can grow potatoes directly from seed. Alternatively, perhaps more likely, specialised growers will produce tubers of potatoes from seed; these tubers are then sold as seed tubers to other potato farmers, who then continue their normal practices of producing potatoes for the market from tubers.”

Financial benefits

Prof Franke says farmers have reason to get excited. “Seed potatoes will reduce input costs, as varieties with enhanced tolerance to pests and diseases require less pesticides. Planting one hectare of potatoes requires three to four tonnes of potato tubers, but only one 25 g packet of potato seeds.” Since potatoes are a more valuable commodity than maize, this technology might also increase farmers’ income potential.

News Archive

UFS doctors fight childhood cancer
2016-09-02

Description: Childhood cancer  Tags: Childhood cancer

Prof David Stones and Dr Jan du Plessis of the
University of Free State’s paediatric oncology ward
are helping little lives, one patient at a time.
Photo: Nonsindiso Qwabe

Of 23 paediatric oncology specialists nationally, Prof David Stones and Dr Jan du Plessis of the University of Free State are the only ones in the province.

Committed to giving holistic care to their patients, the two doctors specialise in all types of childhood cancers, the most common being leukaemia, brain tumour, and nephroblastoma.

They describe the childhood malignancy as a lethal disease, unpredictability being its harshest trait. “With cancer, you can just never know. It precipitates and multiplies, and leads to the failure of other organs. You can just always hope, and keep trying,” said Du Plessis.

The paediatric oncology unit of the Universitas Academic Hospital, their unit, is the liveliest floor in the entire building. It is also the third busiest in South Africa, serving a demographic that spans the Free State and Northern Cape, as well as parts of North West, Eastern Cape and Lesotho.

Each year, the unit receives more than 100 new childhood cancer patients. In 2015, the unit had 113 newly diagnosed patients, an increase from 93 in 2014.

Lack of knowledge poses a serious challenge
According to the two experts, the lack of insight and awareness of the disease remain a big challenge to fighting it. “It is frustrating. Parents and family members don’t know anything about it. Nurses and doctors aren’t always clinically trained to pick up the early warning signs. By the time a diagnosis is made, life and death is on a 50% margin,” Stones said.

Poverty, a lack of resources, overcrowding and a range of health issues are other factors that have a profound effect on the diagnosis and treatment of the disease.

Making a contribution that will last
With a desire to see an improvement on life outcomes in the health sector, the team is focusing on educating the country’s doctors of tomorrow. Their unit is the only one in the country that actively involves medical students in an oncology unit, giving them practical experience and exposure to the individual cases each patient presents. They have also produced a substantial amount of research literature on childhood malignancies in South Africa as a developing country.

Driven by passion to see a better South Africa
The doctors are passionate about the work they do, and remain hopeful there will be a change in the incidence of childhood cancer   not just in decreased levels of the disease, but also in the overall state of well-being of young South Africans.

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