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07 July 2025 | Story Martinette Brits | Photo Charl Devenish
NAS Conference
Leaders in science and innovation at the NAS Research Conference 2025. From the left: Prof Samuel Adelabu (Vice-Dean: Research and Postgraduate Studies in NAS), Prof Vasu Reddy (Deputy Vice-Chancellor: Research and Internationalisation), Prof Bonang Mohale (Chancellor), Prof Paul Oberholster (Dean of NAS), Dr Alba du Toit (Research Chair: Innovative Agro-Processing for Climate-Smart Food Systems), and Prof Daryl Codron (Department of Zoology and Entomology).

The inaugural Faculty of Natural and Agricultural Sciences (NAS) Research Conference at the University of the Free State (UFS) signalled a decisive shift in how science is being imagined and practised at the institution. The two-day gathering, which took place on 1 and 2 July 2025, not only showcased research excellence, but also marked the official launch of two flagship initiatives: the Green Futures Hub and the Complex Systems Hub. Both are designed to enable transdisciplinary research that connects across fields, responds to global and local challenges, and contributes to the university’s Vision 130 strategy.

The conference theme, Integrating science for societal impact and a sustainable future, framed the programme, which featured presentations by researchers, postgraduate students, and postdoctoral fellows across all NAS disciplines. Opening the event, Prof Paul Oberholster, Dean of the Faculty of Natural and Agricultural Sciences, said: “This is more than a research gathering. It’s a signal – a step forward in our faculty’s approach to science, innovation, and impact.”

He emphasised that in a world marked by climate instability, digital disruption, and growing inequality, science must step forward not only to understand the world, but also to help shape it. “Our goal is to create research pathways that are sustainable, collaborative, and responsive to both local and global needs,” he said. The Green Futures Hub and the Complex Systems Hub are practical, future-facing platforms that make that vision real – connecting researchers, government, industry, and communities, he explained.

 

A catalyst for agricultural and environmental transformation

Prof Wayne Truter, Executive Manager of the Green Futures Hub, introduced the initiative as a catalyst for bringing applied science and sustainability together. He asked how innovation can translate into practical solutions that serve society and the environment. “We often focus so deeply on our disciplines that we forget to ask how our work creates social and economic impact,” he said.

The Green Futures Hub is a virtual platform and flagship of agricultural and environmental stewardship and sustainable development. It fosters partnerships that unleash value through nature-based solutions, land rehabilitation, climate risk finance, water resource management, bio-energy innovations, and more – by connecting researchers with industry, government, and international stakeholders. It also supports initiatives that enhance food and water security, investigate the coexistence of mining and agriculture, and address the carbon and nitrogen economy. The hub serves as a space for funding, knowledge transfer, and community transformation.

Prof Truter noted that complex societal challenges – from sustainable agriculture to the energy transition – cannot be solved by isolated disciplines. “Research must be applied in ways that industry and communities can understand and value,” he said. “If we want businesses to believe in science, we must speak their language and show relevance. The Green Futures Hub exists to bridge that gap.”

 

Science that responds to complexity

Prof Oberholster explained that the faculty’s second major initiative – the Complex Systems Hub – is designed to equip researchers to solve pressing problems in a digitally interconnected age. By bringing together data science, AI, advanced modelling, and interdisciplinary design, the hub strengthens the university’s ability to respond to global challenges.

“These are not abstract concepts,” he said. “They are practical responses to the question: how can we do science that matters?”

Dr Jacques Maritz, Head of the Unit for Engineering Sciences, who presented the launch, emphasised that complexity is not a threat to science – it is a source of innovation. “Scalability, unpredictability, nonlinearity, and emergence – these aren’t just buzzwords. They define the future of research.”

The Complex Systems Hub is a digital platform that enables agile, multidisciplinary teams to develop integrated responses to major issues such as climate change, pandemics, and space science. It connects NAS entities such as the Green Futures Hub, the One Health Centre of Excellence, and Advanced Materials Research to foster collaboration and innovation.

Dr Maritz explained that the hub bridges academic research and real-world application by creating spaces where diverse fields intersect. “If we want research to move from lab scale to real-world solutions, we need diverse teams working together – no single field can do this alone.”

Current projects include eco-friendly materials for sustainable construction, scientific water management using algae, and genomic surveillance for public health – all united by one goal: to turn complexity into opportunity and data into direction.

 

Bringing research closer to impact

Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, officially opened the conference and praised the faculty for its foresight and leadership. “This conference is not only about exchanging ideas,” he said, “but about igniting conversations that matter.” Science, he noted, is not a luxury of the privileged, but “the lifeblood of progress,” and its success must be measured not only in citations but in consequences.

He reminded delegates that global challenges such as climate change, food insecurity, and biodiversity loss are no longer distant threats, but urgent realities. “Science must respond – not with silence, but with solutions and deeper questions.”

Referencing the university’s Vision 130 strategy, Prof Reddy said the goal is not just to be research-intensive, but to reimagine the role of science in society. “The world doesn’t necessarily need more data,” he said. “It needs more direction. If our research does not touch lives, it is not reaching far enough.”

He described the conference as a space to “plant ideas, cross-pollinate disciplines, and harvest innovation,” and applauded the launch of the two new research hubs as engines of hope and practical impact. Addressing postgraduate students and early-career researchers directly, he encouraged them to be curious, collaborative, and courageous: “You are not simply here to follow footsteps. You are here to forge new paths.”

 

Building a future grounded in our own narratives

Prof Bonang Mohale, the Chancellor, reminded delegates that science cannot be separated from history, context, or social justice. Quoting Emeritus Professor J Edward Chamberlin, he asked: “If this is your land, where are your stories?” He challenged researchers to ensure that science is not only excellent but also rooted in African realities and driven by the desire to transform society.

“Those nations that make English compulsory but agriculture optional are destined to produce a citizenry that speaks fluently – but on an empty stomach,” he said. “We must do science that describes, defines, and shapes this country in our own image.”

 

A faculty on the move

Over the two-day programme, students and researchers presented cutting-edge work aligned with the faculty’s wide range of disciplines and the university’s strategic research goals. The conference replaced the Flash Fact competition as NAS’s flagship research platform.

In closing, Prof Oberholster invited delegates to make the most of the opportunity to engage across disciplines. “Let’s ensure that the science we do here continues to transform lives – locally, nationally, and globally.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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