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07 July 2025 | Story Martinette Brits | Photo Charl Devenish
NAS Conference
Leaders in science and innovation at the NAS Research Conference 2025. From the left: Prof Samuel Adelabu (Vice-Dean: Research and Postgraduate Studies in NAS), Prof Vasu Reddy (Deputy Vice-Chancellor: Research and Internationalisation), Prof Bonang Mohale (Chancellor), Prof Paul Oberholster (Dean of NAS), Dr Alba du Toit (Research Chair: Innovative Agro-Processing for Climate-Smart Food Systems), and Prof Daryl Codron (Department of Zoology and Entomology).

The inaugural Faculty of Natural and Agricultural Sciences (NAS) Research Conference at the University of the Free State (UFS) signalled a decisive shift in how science is being imagined and practised at the institution. The two-day gathering, which took place on 1 and 2 July 2025, not only showcased research excellence, but also marked the official launch of two flagship initiatives: the Green Futures Hub and the Complex Systems Hub. Both are designed to enable transdisciplinary research that connects across fields, responds to global and local challenges, and contributes to the university’s Vision 130 strategy.

The conference theme, Integrating science for societal impact and a sustainable future, framed the programme, which featured presentations by researchers, postgraduate students, and postdoctoral fellows across all NAS disciplines. Opening the event, Prof Paul Oberholster, Dean of the Faculty of Natural and Agricultural Sciences, said: “This is more than a research gathering. It’s a signal – a step forward in our faculty’s approach to science, innovation, and impact.”

He emphasised that in a world marked by climate instability, digital disruption, and growing inequality, science must step forward not only to understand the world, but also to help shape it. “Our goal is to create research pathways that are sustainable, collaborative, and responsive to both local and global needs,” he said. The Green Futures Hub and the Complex Systems Hub are practical, future-facing platforms that make that vision real – connecting researchers, government, industry, and communities, he explained.

 

A catalyst for agricultural and environmental transformation

Prof Wayne Truter, Executive Manager of the Green Futures Hub, introduced the initiative as a catalyst for bringing applied science and sustainability together. He asked how innovation can translate into practical solutions that serve society and the environment. “We often focus so deeply on our disciplines that we forget to ask how our work creates social and economic impact,” he said.

The Green Futures Hub is a virtual platform and flagship of agricultural and environmental stewardship and sustainable development. It fosters partnerships that unleash value through nature-based solutions, land rehabilitation, climate risk finance, water resource management, bio-energy innovations, and more – by connecting researchers with industry, government, and international stakeholders. It also supports initiatives that enhance food and water security, investigate the coexistence of mining and agriculture, and address the carbon and nitrogen economy. The hub serves as a space for funding, knowledge transfer, and community transformation.

Prof Truter noted that complex societal challenges – from sustainable agriculture to the energy transition – cannot be solved by isolated disciplines. “Research must be applied in ways that industry and communities can understand and value,” he said. “If we want businesses to believe in science, we must speak their language and show relevance. The Green Futures Hub exists to bridge that gap.”

 

Science that responds to complexity

Prof Oberholster explained that the faculty’s second major initiative – the Complex Systems Hub – is designed to equip researchers to solve pressing problems in a digitally interconnected age. By bringing together data science, AI, advanced modelling, and interdisciplinary design, the hub strengthens the university’s ability to respond to global challenges.

“These are not abstract concepts,” he said. “They are practical responses to the question: how can we do science that matters?”

Dr Jacques Maritz, Head of the Unit for Engineering Sciences, who presented the launch, emphasised that complexity is not a threat to science – it is a source of innovation. “Scalability, unpredictability, nonlinearity, and emergence – these aren’t just buzzwords. They define the future of research.”

The Complex Systems Hub is a digital platform that enables agile, multidisciplinary teams to develop integrated responses to major issues such as climate change, pandemics, and space science. It connects NAS entities such as the Green Futures Hub, the One Health Centre of Excellence, and Advanced Materials Research to foster collaboration and innovation.

Dr Maritz explained that the hub bridges academic research and real-world application by creating spaces where diverse fields intersect. “If we want research to move from lab scale to real-world solutions, we need diverse teams working together – no single field can do this alone.”

Current projects include eco-friendly materials for sustainable construction, scientific water management using algae, and genomic surveillance for public health – all united by one goal: to turn complexity into opportunity and data into direction.

 

Bringing research closer to impact

Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, officially opened the conference and praised the faculty for its foresight and leadership. “This conference is not only about exchanging ideas,” he said, “but about igniting conversations that matter.” Science, he noted, is not a luxury of the privileged, but “the lifeblood of progress,” and its success must be measured not only in citations but in consequences.

He reminded delegates that global challenges such as climate change, food insecurity, and biodiversity loss are no longer distant threats, but urgent realities. “Science must respond – not with silence, but with solutions and deeper questions.”

Referencing the university’s Vision 130 strategy, Prof Reddy said the goal is not just to be research-intensive, but to reimagine the role of science in society. “The world doesn’t necessarily need more data,” he said. “It needs more direction. If our research does not touch lives, it is not reaching far enough.”

He described the conference as a space to “plant ideas, cross-pollinate disciplines, and harvest innovation,” and applauded the launch of the two new research hubs as engines of hope and practical impact. Addressing postgraduate students and early-career researchers directly, he encouraged them to be curious, collaborative, and courageous: “You are not simply here to follow footsteps. You are here to forge new paths.”

 

Building a future grounded in our own narratives

Prof Bonang Mohale, the Chancellor, reminded delegates that science cannot be separated from history, context, or social justice. Quoting Emeritus Professor J Edward Chamberlin, he asked: “If this is your land, where are your stories?” He challenged researchers to ensure that science is not only excellent but also rooted in African realities and driven by the desire to transform society.

“Those nations that make English compulsory but agriculture optional are destined to produce a citizenry that speaks fluently – but on an empty stomach,” he said. “We must do science that describes, defines, and shapes this country in our own image.”

 

A faculty on the move

Over the two-day programme, students and researchers presented cutting-edge work aligned with the faculty’s wide range of disciplines and the university’s strategic research goals. The conference replaced the Flash Fact competition as NAS’s flagship research platform.

In closing, Prof Oberholster invited delegates to make the most of the opportunity to engage across disciplines. “Let’s ensure that the science we do here continues to transform lives – locally, nationally, and globally.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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