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07 July 2025 | Story Martinette Brits | Photo Charl Devenish
NAS Conference
Leaders in science and innovation at the NAS Research Conference 2025. From the left: Prof Samuel Adelabu (Vice-Dean: Research and Postgraduate Studies in NAS), Prof Vasu Reddy (Deputy Vice-Chancellor: Research and Internationalisation), Prof Bonang Mohale (Chancellor), Prof Paul Oberholster (Dean of NAS), Dr Alba du Toit (Research Chair: Innovative Agro-Processing for Climate-Smart Food Systems), and Prof Daryl Codron (Department of Zoology and Entomology).

The inaugural Faculty of Natural and Agricultural Sciences (NAS) Research Conference at the University of the Free State (UFS) signalled a decisive shift in how science is being imagined and practised at the institution. The two-day gathering, which took place on 1 and 2 July 2025, not only showcased research excellence, but also marked the official launch of two flagship initiatives: the Green Futures Hub and the Complex Systems Hub. Both are designed to enable transdisciplinary research that connects across fields, responds to global and local challenges, and contributes to the university’s Vision 130 strategy.

The conference theme, Integrating science for societal impact and a sustainable future, framed the programme, which featured presentations by researchers, postgraduate students, and postdoctoral fellows across all NAS disciplines. Opening the event, Prof Paul Oberholster, Dean of the Faculty of Natural and Agricultural Sciences, said: “This is more than a research gathering. It’s a signal – a step forward in our faculty’s approach to science, innovation, and impact.”

He emphasised that in a world marked by climate instability, digital disruption, and growing inequality, science must step forward not only to understand the world, but also to help shape it. “Our goal is to create research pathways that are sustainable, collaborative, and responsive to both local and global needs,” he said. The Green Futures Hub and the Complex Systems Hub are practical, future-facing platforms that make that vision real – connecting researchers, government, industry, and communities, he explained.

 

A catalyst for agricultural and environmental transformation

Prof Wayne Truter, Executive Manager of the Green Futures Hub, introduced the initiative as a catalyst for bringing applied science and sustainability together. He asked how innovation can translate into practical solutions that serve society and the environment. “We often focus so deeply on our disciplines that we forget to ask how our work creates social and economic impact,” he said.

The Green Futures Hub is a virtual platform and flagship of agricultural and environmental stewardship and sustainable development. It fosters partnerships that unleash value through nature-based solutions, land rehabilitation, climate risk finance, water resource management, bio-energy innovations, and more – by connecting researchers with industry, government, and international stakeholders. It also supports initiatives that enhance food and water security, investigate the coexistence of mining and agriculture, and address the carbon and nitrogen economy. The hub serves as a space for funding, knowledge transfer, and community transformation.

Prof Truter noted that complex societal challenges – from sustainable agriculture to the energy transition – cannot be solved by isolated disciplines. “Research must be applied in ways that industry and communities can understand and value,” he said. “If we want businesses to believe in science, we must speak their language and show relevance. The Green Futures Hub exists to bridge that gap.”

 

Science that responds to complexity

Prof Oberholster explained that the faculty’s second major initiative – the Complex Systems Hub – is designed to equip researchers to solve pressing problems in a digitally interconnected age. By bringing together data science, AI, advanced modelling, and interdisciplinary design, the hub strengthens the university’s ability to respond to global challenges.

“These are not abstract concepts,” he said. “They are practical responses to the question: how can we do science that matters?”

Dr Jacques Maritz, Head of the Unit for Engineering Sciences, who presented the launch, emphasised that complexity is not a threat to science – it is a source of innovation. “Scalability, unpredictability, nonlinearity, and emergence – these aren’t just buzzwords. They define the future of research.”

The Complex Systems Hub is a digital platform that enables agile, multidisciplinary teams to develop integrated responses to major issues such as climate change, pandemics, and space science. It connects NAS entities such as the Green Futures Hub, the One Health Centre of Excellence, and Advanced Materials Research to foster collaboration and innovation.

Dr Maritz explained that the hub bridges academic research and real-world application by creating spaces where diverse fields intersect. “If we want research to move from lab scale to real-world solutions, we need diverse teams working together – no single field can do this alone.”

Current projects include eco-friendly materials for sustainable construction, scientific water management using algae, and genomic surveillance for public health – all united by one goal: to turn complexity into opportunity and data into direction.

 

Bringing research closer to impact

Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, officially opened the conference and praised the faculty for its foresight and leadership. “This conference is not only about exchanging ideas,” he said, “but about igniting conversations that matter.” Science, he noted, is not a luxury of the privileged, but “the lifeblood of progress,” and its success must be measured not only in citations but in consequences.

He reminded delegates that global challenges such as climate change, food insecurity, and biodiversity loss are no longer distant threats, but urgent realities. “Science must respond – not with silence, but with solutions and deeper questions.”

Referencing the university’s Vision 130 strategy, Prof Reddy said the goal is not just to be research-intensive, but to reimagine the role of science in society. “The world doesn’t necessarily need more data,” he said. “It needs more direction. If our research does not touch lives, it is not reaching far enough.”

He described the conference as a space to “plant ideas, cross-pollinate disciplines, and harvest innovation,” and applauded the launch of the two new research hubs as engines of hope and practical impact. Addressing postgraduate students and early-career researchers directly, he encouraged them to be curious, collaborative, and courageous: “You are not simply here to follow footsteps. You are here to forge new paths.”

 

Building a future grounded in our own narratives

Prof Bonang Mohale, the Chancellor, reminded delegates that science cannot be separated from history, context, or social justice. Quoting Emeritus Professor J Edward Chamberlin, he asked: “If this is your land, where are your stories?” He challenged researchers to ensure that science is not only excellent but also rooted in African realities and driven by the desire to transform society.

“Those nations that make English compulsory but agriculture optional are destined to produce a citizenry that speaks fluently – but on an empty stomach,” he said. “We must do science that describes, defines, and shapes this country in our own image.”

 

A faculty on the move

Over the two-day programme, students and researchers presented cutting-edge work aligned with the faculty’s wide range of disciplines and the university’s strategic research goals. The conference replaced the Flash Fact competition as NAS’s flagship research platform.

In closing, Prof Oberholster invited delegates to make the most of the opportunity to engage across disciplines. “Let’s ensure that the science we do here continues to transform lives – locally, nationally, and globally.”

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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