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07 July 2025 | Story Martinette Brits | Photo Charl Devenish
NAS Conference
Leaders in science and innovation at the NAS Research Conference 2025. From the left: Prof Samuel Adelabu (Vice-Dean: Research and Postgraduate Studies in NAS), Prof Vasu Reddy (Deputy Vice-Chancellor: Research and Internationalisation), Prof Bonang Mohale (Chancellor), Prof Paul Oberholster (Dean of NAS), Dr Alba du Toit (Research Chair: Innovative Agro-Processing for Climate-Smart Food Systems), and Prof Daryl Codron (Department of Zoology and Entomology).

The inaugural Faculty of Natural and Agricultural Sciences (NAS) Research Conference at the University of the Free State (UFS) signalled a decisive shift in how science is being imagined and practised at the institution. The two-day gathering, which took place on 1 and 2 July 2025, not only showcased research excellence, but also marked the official launch of two flagship initiatives: the Green Futures Hub and the Complex Systems Hub. Both are designed to enable transdisciplinary research that connects across fields, responds to global and local challenges, and contributes to the university’s Vision 130 strategy.

The conference theme, Integrating science for societal impact and a sustainable future, framed the programme, which featured presentations by researchers, postgraduate students, and postdoctoral fellows across all NAS disciplines. Opening the event, Prof Paul Oberholster, Dean of the Faculty of Natural and Agricultural Sciences, said: “This is more than a research gathering. It’s a signal – a step forward in our faculty’s approach to science, innovation, and impact.”

He emphasised that in a world marked by climate instability, digital disruption, and growing inequality, science must step forward not only to understand the world, but also to help shape it. “Our goal is to create research pathways that are sustainable, collaborative, and responsive to both local and global needs,” he said. The Green Futures Hub and the Complex Systems Hub are practical, future-facing platforms that make that vision real – connecting researchers, government, industry, and communities, he explained.

 

A catalyst for agricultural and environmental transformation

Prof Wayne Truter, Executive Manager of the Green Futures Hub, introduced the initiative as a catalyst for bringing applied science and sustainability together. He asked how innovation can translate into practical solutions that serve society and the environment. “We often focus so deeply on our disciplines that we forget to ask how our work creates social and economic impact,” he said.

The Green Futures Hub is a virtual platform and flagship of agricultural and environmental stewardship and sustainable development. It fosters partnerships that unleash value through nature-based solutions, land rehabilitation, climate risk finance, water resource management, bio-energy innovations, and more – by connecting researchers with industry, government, and international stakeholders. It also supports initiatives that enhance food and water security, investigate the coexistence of mining and agriculture, and address the carbon and nitrogen economy. The hub serves as a space for funding, knowledge transfer, and community transformation.

Prof Truter noted that complex societal challenges – from sustainable agriculture to the energy transition – cannot be solved by isolated disciplines. “Research must be applied in ways that industry and communities can understand and value,” he said. “If we want businesses to believe in science, we must speak their language and show relevance. The Green Futures Hub exists to bridge that gap.”

 

Science that responds to complexity

Prof Oberholster explained that the faculty’s second major initiative – the Complex Systems Hub – is designed to equip researchers to solve pressing problems in a digitally interconnected age. By bringing together data science, AI, advanced modelling, and interdisciplinary design, the hub strengthens the university’s ability to respond to global challenges.

“These are not abstract concepts,” he said. “They are practical responses to the question: how can we do science that matters?”

Dr Jacques Maritz, Head of the Unit for Engineering Sciences, who presented the launch, emphasised that complexity is not a threat to science – it is a source of innovation. “Scalability, unpredictability, nonlinearity, and emergence – these aren’t just buzzwords. They define the future of research.”

The Complex Systems Hub is a digital platform that enables agile, multidisciplinary teams to develop integrated responses to major issues such as climate change, pandemics, and space science. It connects NAS entities such as the Green Futures Hub, the One Health Centre of Excellence, and Advanced Materials Research to foster collaboration and innovation.

Dr Maritz explained that the hub bridges academic research and real-world application by creating spaces where diverse fields intersect. “If we want research to move from lab scale to real-world solutions, we need diverse teams working together – no single field can do this alone.”

Current projects include eco-friendly materials for sustainable construction, scientific water management using algae, and genomic surveillance for public health – all united by one goal: to turn complexity into opportunity and data into direction.

 

Bringing research closer to impact

Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, officially opened the conference and praised the faculty for its foresight and leadership. “This conference is not only about exchanging ideas,” he said, “but about igniting conversations that matter.” Science, he noted, is not a luxury of the privileged, but “the lifeblood of progress,” and its success must be measured not only in citations but in consequences.

He reminded delegates that global challenges such as climate change, food insecurity, and biodiversity loss are no longer distant threats, but urgent realities. “Science must respond – not with silence, but with solutions and deeper questions.”

Referencing the university’s Vision 130 strategy, Prof Reddy said the goal is not just to be research-intensive, but to reimagine the role of science in society. “The world doesn’t necessarily need more data,” he said. “It needs more direction. If our research does not touch lives, it is not reaching far enough.”

He described the conference as a space to “plant ideas, cross-pollinate disciplines, and harvest innovation,” and applauded the launch of the two new research hubs as engines of hope and practical impact. Addressing postgraduate students and early-career researchers directly, he encouraged them to be curious, collaborative, and courageous: “You are not simply here to follow footsteps. You are here to forge new paths.”

 

Building a future grounded in our own narratives

Prof Bonang Mohale, the Chancellor, reminded delegates that science cannot be separated from history, context, or social justice. Quoting Emeritus Professor J Edward Chamberlin, he asked: “If this is your land, where are your stories?” He challenged researchers to ensure that science is not only excellent but also rooted in African realities and driven by the desire to transform society.

“Those nations that make English compulsory but agriculture optional are destined to produce a citizenry that speaks fluently – but on an empty stomach,” he said. “We must do science that describes, defines, and shapes this country in our own image.”

 

A faculty on the move

Over the two-day programme, students and researchers presented cutting-edge work aligned with the faculty’s wide range of disciplines and the university’s strategic research goals. The conference replaced the Flash Fact competition as NAS’s flagship research platform.

In closing, Prof Oberholster invited delegates to make the most of the opportunity to engage across disciplines. “Let’s ensure that the science we do here continues to transform lives – locally, nationally, and globally.”

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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