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21 July 2025 | Story Dr Nitha Ramnath | Photo Supplied
Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, and Prof Saleem Badat, Research Professor in the UFS Department of History, launch a new book honouring Ruth First’s activist legacy and scholarly impact.

On 16 July, during the Free State Arts Festival, the University of the Free State (UFS) launched Research and Activism: Ruth First & Activist Research, an incisive edited volume by Professors Vasu Reddy, Deputy Vice-Chancellor, Research and Internationalisation at the UFS, and Saleem Badat, Research Professor in the UFS Department of History

The event was facilitated by Prof Christian Williams, Associate Professor of Anthropology, with Prof Reddy delivering the keynote address and Dr Lazlo Passemiers, Senior Lecturer in History, serving as respondent.

The important new work pays tribute to Ruth First - South African freedom fighter, journalist, intellectual, and scholar-activist, who’s unflinching pursuit of justice continues to resonate. Far from a closed chapter in South Africa’s struggle history, First’s legacy remains a compelling call to action for contemporary scholars, activists, and institutions: to confront injustice, speak with conviction, and pursue research rooted in ethical action. 

 

A legacy of fearless scholarship

Ruth First’s activism was grounded in refusal to remain silent in the face of injustice. As a tenacious investigative journalist and public intellectual, she exposed the systemic violence of apartheid and challenged power through sharp incisive analysis and courageous advocacy. Her life, and her assassination by apartheid operatives in 1982, exemplify the personal and political costs of speaking truth to power.

Prof Vasu Reddy reflected that First “theorised, analysed, and connected the dots between racism, capitalism, and oppression, and refused to dilute her message for mass appeal.” Her words”, he said, “unsettled because they were true. Her activism “compels us to speak courageously, think critically, and act ethically. She turned ideas into instruments of liberation.”

 

Beyond the ivory tower 

With contributions from 17 scholars, the volume examines themes ranging from climate justice and activism in Marikana to the ethics of legal practice, community engagement, and the role of the university in social transformation. 

Prof Reddy emphasised that Ruth First’s example disrupts the traditional notions of academia. “Universities must be engines of social change, not ivory towers,” he argued. “Her legacy reminds us that activist research is about standing with the marginalised, and not merely studying them.” 

Dr Passemiers echoed this view, describing First as one of South Africa’s foremost examples of blending impactful activism with rigorous scholarship. “Her activism was often transnational, connecting South Africa’s liberation struggle with broader regional movements. This perspective is especially relevant today, as many of our challenges transcend national borders.”

He added that the book should be required reading for students in the social sciences and humanities, as it “challenges misconceptions about activist research and shows how scholarship can contribute meaningfully to public life, beyond academic debate.”

 

Redefining academic activism 

Prof Christian Williams underscored one of the book’s central provocations: to set a litmus test for genuine activist research. He argued that activism and scholarship can compete with one another, but should, following First’s example, be intersecting commitments. “There is no true academic neutrality,” he noted.

Members of the audience also touched on related themes pertaining to the role of universities in society, responding to the book’s content as narrated at the launch. For example, the collection interrogates how universities often claim to be ‘engaged’ while aligning primarily with business, the state, and elite interests. True activist research, the contributors argue, must connect with social movements and confront power, not shy away from it. Members of the audience reflected on this point, considering what it means for researchers to do activist research amidst attacks on social justice-oriented programmes in higher education globally. 

In Prof Reddy’s final comments, he returned to the importance of First for debates about the university’s role. “This is unfinished business. The story of Ruth First, and of activist scholarship, is not fully told”, says Prof Reddy. As he noted, Research and Activism offers both a tribute to Ruth First and a powerful reminder of the work still to be done. “Her life triggers us to think deeply about real-world issues, not as abstract concepts but as urgent matters of justice and humanity.”

Research and Activism: Ruth First & Activist Research is available for free download via the ESI Press website.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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