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21 July 2025 | Story Dr Nitha Ramnath | Photo Supplied
Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, and Prof Saleem Badat, Research Professor in the UFS Department of History, launch a new book honouring Ruth First’s activist legacy and scholarly impact.

On 16 July, during the Free State Arts Festival, the University of the Free State (UFS) launched Research and Activism: Ruth First & Activist Research, an incisive edited volume by Professors Vasu Reddy, Deputy Vice-Chancellor, Research and Internationalisation at the UFS, and Saleem Badat, Research Professor in the UFS Department of History

The event was facilitated by Prof Christian Williams, Associate Professor of Anthropology, with Prof Reddy delivering the keynote address and Dr Lazlo Passemiers, Senior Lecturer in History, serving as respondent.

The important new work pays tribute to Ruth First - South African freedom fighter, journalist, intellectual, and scholar-activist, who’s unflinching pursuit of justice continues to resonate. Far from a closed chapter in South Africa’s struggle history, First’s legacy remains a compelling call to action for contemporary scholars, activists, and institutions: to confront injustice, speak with conviction, and pursue research rooted in ethical action. 

 

A legacy of fearless scholarship

Ruth First’s activism was grounded in refusal to remain silent in the face of injustice. As a tenacious investigative journalist and public intellectual, she exposed the systemic violence of apartheid and challenged power through sharp incisive analysis and courageous advocacy. Her life, and her assassination by apartheid operatives in 1982, exemplify the personal and political costs of speaking truth to power.

Prof Vasu Reddy reflected that First “theorised, analysed, and connected the dots between racism, capitalism, and oppression, and refused to dilute her message for mass appeal.” Her words”, he said, “unsettled because they were true. Her activism “compels us to speak courageously, think critically, and act ethically. She turned ideas into instruments of liberation.”

 

Beyond the ivory tower 

With contributions from 17 scholars, the volume examines themes ranging from climate justice and activism in Marikana to the ethics of legal practice, community engagement, and the role of the university in social transformation. 

Prof Reddy emphasised that Ruth First’s example disrupts the traditional notions of academia. “Universities must be engines of social change, not ivory towers,” he argued. “Her legacy reminds us that activist research is about standing with the marginalised, and not merely studying them.” 

Dr Passemiers echoed this view, describing First as one of South Africa’s foremost examples of blending impactful activism with rigorous scholarship. “Her activism was often transnational, connecting South Africa’s liberation struggle with broader regional movements. This perspective is especially relevant today, as many of our challenges transcend national borders.”

He added that the book should be required reading for students in the social sciences and humanities, as it “challenges misconceptions about activist research and shows how scholarship can contribute meaningfully to public life, beyond academic debate.”

 

Redefining academic activism 

Prof Christian Williams underscored one of the book’s central provocations: to set a litmus test for genuine activist research. He argued that activism and scholarship can compete with one another, but should, following First’s example, be intersecting commitments. “There is no true academic neutrality,” he noted.

Members of the audience also touched on related themes pertaining to the role of universities in society, responding to the book’s content as narrated at the launch. For example, the collection interrogates how universities often claim to be ‘engaged’ while aligning primarily with business, the state, and elite interests. True activist research, the contributors argue, must connect with social movements and confront power, not shy away from it. Members of the audience reflected on this point, considering what it means for researchers to do activist research amidst attacks on social justice-oriented programmes in higher education globally. 

In Prof Reddy’s final comments, he returned to the importance of First for debates about the university’s role. “This is unfinished business. The story of Ruth First, and of activist scholarship, is not fully told”, says Prof Reddy. As he noted, Research and Activism offers both a tribute to Ruth First and a powerful reminder of the work still to be done. “Her life triggers us to think deeply about real-world issues, not as abstract concepts but as urgent matters of justice and humanity.”

Research and Activism: Ruth First & Activist Research is available for free download via the ESI Press website.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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