Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
25 June 2025 | Story Andre Damons | Photo Andre Damons
Prof Matlalepula Matsabisa
Prof Motlalepula Matsabisa, renowned African Traditional Medicine expert and pharmacology researcher from the University of the Free State (UFS) will co-chair the World Health Organisation Global Traditional Medicine Summit steering committee.

Prof Motlalepula Matsabisa, renowned African Traditional Medicine expert and pharmacology researcher from the University of the Free State (UFS) has recently been elected a co-chairperson of the World Health Organisation (WHO) Global Traditional Medicine Summit steering committee. The other co-chairperson is Dr Goh Cheng Soon from Malaysia. 

The steering committee, which is appointed for one year, will help the WHO to organise the WHO Traditional Medicines Global Summit taking place later this year in New Delhi, India. The steering committee is also an advisory body to the WHO and the Global Traditional Medicine Centre to provide reviews and recommendations for the WHO Traditional Medicine Global Summit coordination, propose summit sessions and session speakers. This committee has 15 members from South Africa, Malaysia, Saudi Arabia, Ghana, India, China, Bhutan, Germany, Brazil, Egypt, New Zealand, US, Netherlands, Switzerland and Bolivia.

Prof Matsabisa, Research Director of the African Medicines Innovations and Technologies Development (AMITD) platform at the UFS, is also the chairperson of the WHO Africa Regional Expert Advisory Committee on Traditional Medicine (REACT)

 

Responsibility of the committee 

“Once more this is an honour for me to take this task and lead a group of experts – not just from the African continent where I am currently the chairperson of the WHO Afro REACT committee, but now I chair experts from all the continents and all six WHO geographical regions – namely Africa (Afro), the Americas (AMRO), the eastern Mediterranean (EMRO), Europe (EURO), South East Asia (SEARO) and the Western Pacific (WPRO). I chair a worldwide group of experts,” says Prof Matsabisa. 

According to him, the committee will work with WHO to design the summit programme, identify summit sessions and session speakers, as well as recommend ministers to be in the round-table discussions. The committee will also be responsible for the design of the exhibitions that will showcase traditional medicine products and practices across all six WHO regions. The identification of the sessions will be around action and delivery on the priority agenda from the past 2023 WHO Global summit as well as from the deliverables of the WHO 2025-2034 Traditional Medicines strategy. 

The theme for the WHO Traditional Medicines Global Summit is “Restoring balance for people and planet. The science and practice of health and well-being”. They anticipate attracting 6 000 people, from all over, to attend the summit with at least 1 000 in-person attendees and another 5 000 online participants. 

The committee will look at the first WHO 2023 Traditional Medicines Global summit and its Gujarat Declaration where the Traditional Medicine (TM) priority agenda was set – this priority agenda included global leadership, research and evidence, universal health coverage (UHC), primary health care (PHC) health systems, data and routine information systems, biodiversity and sustainability.

 

Market the UFS 

When a call for applications to serve on the steering committee went out, Prof Matsabisa applied and was later approached by the WHO to chair the steering and advisory committee. “I see this as an opportunity to serve the WHO and use my knowledge and skills to serve the world. I felt very honoured to have been approached for such an important job and role to undertake. As a chairperson, I will guide the committee, take responsibility for the planning and implementation of the summit. I will market the summit. I shall be the direct link between the WHO in Geneva and the committee.”

Prof Matsabisa indicated that he will use the chairmanship to market and internationalise the UFS AMITD programme and give it a further global outlook. He will also find new collaborators and potential funders and investors for projects and activities of the UFS and secure activities that will help find and fund global postdoctoral fellows and visiting scholars. This will be good for the AMITD platform.

“The steering committee shall set the 2nd WHO Traditional Medicine Global Summit theme for scale up learning, collaboration and action,” says Prof Matsabisa. “Therefore, the committee will design the summit programme to address these and take themes and discussions from high-level political commitments, building on UNGA, WHA, G20, BRICS, and AU etc. Launches of the WHO Global TM Library on Traditional Medicine; WHO Bulletin special issue on Traditional Medicine; TM Innovation and Investment Initiative; Global TM Research Roadmap; Global TM Data Network; and Learnings from Indigenous Knowledge will also take place.”

Furthermore, advancements of healthy ecosystems and TM integration and encouraging indigenous people's knowledge exchange; and AI and TM governance course/ brief as well as the advancing of cross-cutting frameworks for TM-related ethics, rights, IP, equitable access and benefits are on the agenda. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept