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08 May 2025 | Story André Damons | Photo Supplied
Nosicelo Madushana
Nosicelo Madushana, a third-year medical student at the UFS, was four years old when she sustained third-degree burn wounds on 70% of her body.

With winter fast approaching, healthcare professionals in the Free State are gearing up for an increase in burn injuries during these cold months. Many of these injuries are preventable, and doctors and medical staff believe educating communities about common preventive practices can help keep them safe.

Dr Hilge du Preez, Paediatric Surgeon from the University of the Free State (UFS), says they observe an increase in burn injuries, which can be devastating, causing serious bodily harm, long-term disability, and even death, during the winter months.

“As healthcare professionals, we do all we can to help burn injury patients recover and regain their health and activity. However, as with many other conditions, the best treatment for a burn injury is prevention. Thermal burns are the most common type of burn we see. These are caused by contact with hot substances or fluids, such as flames or boiling water. Children and adults sustain burn injuries in different ways.

“While children can suffer burns from flames, they are more likely to burn themselves by spilling hot liquids or food. We also see cases where children accidentally fall into a tub of hot water that is being prepared for a bath,” says Dr Du Preez.

According to Dr Du Preez, when cooking, it is safer to have pot and pan handles turned inward, rather than outward where children can reach them. Kettle cords and tablecloths should be tucked in and kept out of reach to prevent children from pulling them and spilling hot substances.

 

A turning point

Nosicelo Madushana, a third-year medical student at the UFS, was four years old when she sustained third degree burn wounds on 70% of her body after a large pot of boiling water, fell on her. However, she would only later really understand the impact of this accident on her life.

 “It wasn’t until I was in Grade 3 that I began to understand that I was perceived as different. During an Eskom educational session on the dangers of electricity, the presenter used the analogy of turning into a "chicken roast" when tampering with electric circuits. In that moment, a number of my peers turned, pointed, and laughed, likening me to the example given.

“That experience marked a turning point in my self-awareness and emotional resilience. It shaped me profoundly. I became emotionally guarded, not violent, but verbally defensive. I often felt I had to exist in survival mode rather than being allowed to simply be myself,” Nosicelo recalls.

As a result of these experiences, she explains, she developed a deep-seated need to constantly prove that she belonged in every space she entered. She wanted to ensure that any opportunity or recognition she received was based solely on merit and not influenced by perceptions of her physical appearance or sympathy for her circumstances. It became an unhealthy cycle of overcompensation and striving to validate her presence.

This is demonstrated in her academic achievements as she first did a Bachelor of Sciences in Medical Bioscience degree, followed by a postgraduate diploma in Augment and Virtual Reality (Comp Science) (both at University of the Western Cape). She followed this up with an Honours degree in Anatomical Pathology at Sefako Makgathu Health Sciences University.

 

Apply correct first aid treatment immediately

Dr Du Preez says they also recommend that children should never be left unsupervised around hot substances, whether food or fire. When running a bath for a child, add cold water to the tub first, then hot water to reach the desired temperature. This is safer because, if a child falls into the tub, they will only encounter cold water rather than hot, which could prevent a severe, potentially life-threatening injury.

Adults, on the other hand, explains Dr Du Preez, typically sustain severe burns due to flames, which may result from house fires or accidents involving fire. Paraffin stoves are responsible for a significant number of house fires in South Africa, and healthcare professionals strongly advise against their use.

In the era of load-shedding, people need to be mindful of safe practices when using candles, says Dr Du Preez. Candles should never be left unattended and should always be placed in a container that covers the flame. This helps prevent the risk of a candle setting a room on fire if it falls over.

“If someone suffers a burn injury, correct first aid treatment should be applied immediately. Remove any clothing and jewellery from the affected area, and ensure any burning debris is removed. Cool the burn by running it under lukewarm tap water for 10-15 minutes. Cover the wound with a clean, damp cloth and seek medical attention. Do not apply “home remedies” such as toothpaste, raw egg, or shoe polish, as these can impair healing and increase the risk of infection and scarring.

“In the event of a fire, remember to ‘stop, drop, and roll’ to extinguish any flames. Remove burning clothes and debris, cover the person with a clean towel, and seek urgent medical care.”

 

Being burned victim is her normal

Nosicelo, whose passion lies in research and the fight against cancer, being a burn victim is her normal. She has no memory or photographic evidence of herself without burns. “What I dislike the most is the empathetic gaze, the unsolicited pity, the assumption that I am a victim in constant need of help. I am not a tragic story. I am a woman who is brave, resilient, beautiful, and forging her own path.

“My life is not defined by the incident, but by the choices I make and the legacy I intend to leave. I am a three-time graduate, and I will not stop until I attain the prestigious FCPath(SA) qualification (the Fellowship of the College of Pathologists of South Africa, a recognised postgraduate qualification in pathology for medical practitioners in South Africa.) My journey is one of strength, not sorrow. I am committed to being a part of the global effort to eliminate this disease. Until that day comes, I dedicate myself to being a voice for cancer education, prevention, and early detection, empowering individuals with knowledge that can save lives.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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