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08 May 2025 | Story André Damons | Photo Supplied
Nosicelo Madushana
Nosicelo Madushana, a third-year medical student at the UFS, was four years old when she sustained third-degree burn wounds on 70% of her body.

With winter fast approaching, healthcare professionals in the Free State are gearing up for an increase in burn injuries during these cold months. Many of these injuries are preventable, and doctors and medical staff believe educating communities about common preventive practices can help keep them safe.

Dr Hilge du Preez, Paediatric Surgeon from the University of the Free State (UFS), says they observe an increase in burn injuries, which can be devastating, causing serious bodily harm, long-term disability, and even death, during the winter months.

“As healthcare professionals, we do all we can to help burn injury patients recover and regain their health and activity. However, as with many other conditions, the best treatment for a burn injury is prevention. Thermal burns are the most common type of burn we see. These are caused by contact with hot substances or fluids, such as flames or boiling water. Children and adults sustain burn injuries in different ways.

“While children can suffer burns from flames, they are more likely to burn themselves by spilling hot liquids or food. We also see cases where children accidentally fall into a tub of hot water that is being prepared for a bath,” says Dr Du Preez.

According to Dr Du Preez, when cooking, it is safer to have pot and pan handles turned inward, rather than outward where children can reach them. Kettle cords and tablecloths should be tucked in and kept out of reach to prevent children from pulling them and spilling hot substances.

 

A turning point

Nosicelo Madushana, a third-year medical student at the UFS, was four years old when she sustained third degree burn wounds on 70% of her body after a large pot of boiling water, fell on her. However, she would only later really understand the impact of this accident on her life.

 “It wasn’t until I was in Grade 3 that I began to understand that I was perceived as different. During an Eskom educational session on the dangers of electricity, the presenter used the analogy of turning into a "chicken roast" when tampering with electric circuits. In that moment, a number of my peers turned, pointed, and laughed, likening me to the example given.

“That experience marked a turning point in my self-awareness and emotional resilience. It shaped me profoundly. I became emotionally guarded, not violent, but verbally defensive. I often felt I had to exist in survival mode rather than being allowed to simply be myself,” Nosicelo recalls.

As a result of these experiences, she explains, she developed a deep-seated need to constantly prove that she belonged in every space she entered. She wanted to ensure that any opportunity or recognition she received was based solely on merit and not influenced by perceptions of her physical appearance or sympathy for her circumstances. It became an unhealthy cycle of overcompensation and striving to validate her presence.

This is demonstrated in her academic achievements as she first did a Bachelor of Sciences in Medical Bioscience degree, followed by a postgraduate diploma in Augment and Virtual Reality (Comp Science) (both at University of the Western Cape). She followed this up with an Honours degree in Anatomical Pathology at Sefako Makgathu Health Sciences University.

 

Apply correct first aid treatment immediately

Dr Du Preez says they also recommend that children should never be left unsupervised around hot substances, whether food or fire. When running a bath for a child, add cold water to the tub first, then hot water to reach the desired temperature. This is safer because, if a child falls into the tub, they will only encounter cold water rather than hot, which could prevent a severe, potentially life-threatening injury.

Adults, on the other hand, explains Dr Du Preez, typically sustain severe burns due to flames, which may result from house fires or accidents involving fire. Paraffin stoves are responsible for a significant number of house fires in South Africa, and healthcare professionals strongly advise against their use.

In the era of load-shedding, people need to be mindful of safe practices when using candles, says Dr Du Preez. Candles should never be left unattended and should always be placed in a container that covers the flame. This helps prevent the risk of a candle setting a room on fire if it falls over.

“If someone suffers a burn injury, correct first aid treatment should be applied immediately. Remove any clothing and jewellery from the affected area, and ensure any burning debris is removed. Cool the burn by running it under lukewarm tap water for 10-15 minutes. Cover the wound with a clean, damp cloth and seek medical attention. Do not apply “home remedies” such as toothpaste, raw egg, or shoe polish, as these can impair healing and increase the risk of infection and scarring.

“In the event of a fire, remember to ‘stop, drop, and roll’ to extinguish any flames. Remove burning clothes and debris, cover the person with a clean towel, and seek urgent medical care.”

 

Being burned victim is her normal

Nosicelo, whose passion lies in research and the fight against cancer, being a burn victim is her normal. She has no memory or photographic evidence of herself without burns. “What I dislike the most is the empathetic gaze, the unsolicited pity, the assumption that I am a victim in constant need of help. I am not a tragic story. I am a woman who is brave, resilient, beautiful, and forging her own path.

“My life is not defined by the incident, but by the choices I make and the legacy I intend to leave. I am a three-time graduate, and I will not stop until I attain the prestigious FCPath(SA) qualification (the Fellowship of the College of Pathologists of South Africa, a recognised postgraduate qualification in pathology for medical practitioners in South Africa.) My journey is one of strength, not sorrow. I am committed to being a part of the global effort to eliminate this disease. Until that day comes, I dedicate myself to being a voice for cancer education, prevention, and early detection, empowering individuals with knowledge that can save lives.”

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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