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18 May 2025 | Story André Damons | Photo André Damons
Research room
Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics explains how the PEA POD® infant body composition analyser works. Dr Balekile Mzangwa, CEO of Universitas Academic Hospital, and Dr Grace London, Chief Director: District Health services at the Free State Department of Health, listens in.

In a significant stride toward improving maternal and child health in the Free State, the Universitas Academic Hospital, in collaboration with the Faculty of Health Sciences at the University of the Free State (UFS), has launched an innovative Research Room which houses the PEA POD® infant body composition analyser and the Dual-Energy X-ray Absorptiometry (DXA) machine used to assess body composition and bone mineral density.

The initiative, which marks a new era in neonatal care and research, aims to integrate cutting-edge technology into routine clinical care. The PEA POD®, a non-invasive device that uses air displacement plethysmography, allows for precise measurement of fat and fat-free mass in newborns – offering a more accurate assessment of growth and nutritional status than traditional methods. 

The research room is a newly renovated and dedicated space adjacent to the maternity and neonatal units, ensuring quick, safe access to the newborns in the hospital. Two full-time MSc Dietetics students have been trained to perform the PEAPOD® assessments and colleagues from Radiography will perform the DXA assessments. This work lays the foundation for an ongoing maternal and infant body composition database –  a valuable resource for research, clinical care, and policy guidance.

Aligned with national health priorities

According to Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics, this initiative is the result of a multidisciplinary collaboration across Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics, to mention just a few of the collaborators. They are optimistic about the dual impact of this project as it advances academic and clinical research in early-life nutrition and growth as well as enhancing patient care at Universitas Hospital – bringing measurable benefits to mothers and their babies, she said. 

“This initiative is well aligned with national health priorities. According to the South African Early Childhood Review 2024, malnutrition in all its forms remains a significant challenge with short- and long-term consequences for mothers and their babies, especially during the first 1 000 days of life, from conception to the second birthday.

“We know from global and local evidence that growth patterns established during early life have profound and lasting effects on an individual’s health, development, and well-being. Our work at the University of the Free State has focused on the nutritional status of pregnant women and the early environments to which infants are exposed, both during and after pregnancy,” said Prof Walsh. 

However, she continued, in previous studies, they faced a significant challenge: the lack of specialised equipment to accurately measure infant body composition. Traditional measures such as weight and length provide only part of the picture.

 

New possibilities in healthcare, science, and service

Dr Mzangwa said the day not only marks the unveiling of state-of-the-art technology, but the beginning of a new chapter in how they will care for and understand the youngest and most vulnerable patients. The PEA POD® and DXA, which is now housed just steps away from the maternity and neonatal wards, symbolise a shared vision between the hospital and the Faculty of Health Sciences at the UFS: a vision grounded in evidence-based care, cutting-edge research, and above all, compassion.

“We express our sincere appreciation to everyone who supported this initiative. We also acknowledge the dedication of all the collaborating departments – Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics –  and thank Prof Corinna Walsh and Dr Lizzy Tabane for their leadership and insight.”

Prof Janse van Vuuren, said: “Today, we do more than open a physical space. We open the door to new possibilities in healthcare, science, and service to the people of our province. It is a shining example of what can be achieved when government and academia come together, united by a common purpose – to improve lives through knowledge, innovation, and care.”

The technologies that will be used in this facility are more than just advanced instruments, they are tools that allow medical staff to better understand the human body in its earliest and most vulnerable stages, as well as throughout the lifespan. With this understanding comes the ability to make informed decisions, to intervene earlier, and to tailor care in ways that truly meet the needs of our patients, said Prof Janse van Vuuren.

“This space is more than a research centre. It is a testament to our commitment to evidence-based care. It is a place where data meets compassion, where science serves humanity. The work that will happen here will not be confined to the walls of academia –  it has the potential to ripple outward into clinics, into hospitals, and into homes. It will shape guidelines, inform policy, and ultimately, improve outcomes for patients across our province and beyond.”


News Archive

New world-class Chemistry facilities at UFS
2011-11-22

 

A world-class research centre was introduced on Friday 18 November 2011 when the new Chemistry building on the Bloemfontein Campus of the University of the Free State (UFS) was officially opened.
The upgrading of the building, which has taken place over a period of five years, is the UFS’s largest single financial investment in a long time. The building itself has been renovated at a cost of R60 million and, together with the new equipment acquired, the total investment exceeds R110 million. The university has provided the major part of this, with valuable contributions from Sasol and the South African Research Foundation (NRF), which each contributed more than R20 million for different facets and projects.
The senior management of Sasol, NECSA (The South African Nuclear Energy Corporation), PETLabs Pharmaceuticals, and visitors from Sweden attended the opening.

Prof. Andreas Roodt, Head of the Department of Chemistry, states the department’s specialist research areas includes X-ray crystallography, electrochemistry, synthesis of new molecules, the development of new methods to determine rare elements, water purification, as well as the measurement of energy and temperatures responsible for phase changes in molecules, the development of agents to detect cancer and other defects in the body, and many more.

“We have top expertise in various fields, with some of the best equipment and currently competing with the best laboratories in the world. We have collaborative agreements with more than twenty national and international chemistry research groups of note.

“Currently we are providing inputs about technical aspects of the acid mine water in Johannesburg and vicinity, as well as the fracking in the Karoo in order to release shale gas.”

New equipment installed during the upgrading action comprises:

  • X-ray diffractometers (R5 million) for crystal research. Crystals with unknown compounds are researched on an X-ray diffractometer, which determines the distances in angstroms (1 angstrom is a ten-billionth of a metre) and corners between atoms, as well as the arrangement of the atoms in the crystal, and the precise composition of the molecules in the crystal.
  • Differential scanning calorimeter (DSC) for thermographic analyses (R4 million). Heat transfer and the accompanying changes, as in volcanoes, and catalytic reactions for new motor petrol are researched. Temperature changes, coupled with the phase switchover of fluid crystals (liquid crystals -watches, TV screens) of solid matter to fluids, are measured.
  • Nuclear-magnetic resonance (NMR: Bruker 600 MHz; R12 million, one of the most advanced systems in Africa). A NMR apparatus is closely linked with the apparatus for magnetic resonance imaging, which is commonly used in hospitals. NMR is also used to determine the structure of unknown compounds, as well as the purity of the sample. Important structural characteristics of molecules can also be identified, which is extremely important if this molecule is to be used as medication, as well as to predict any possible side effects of it.
  • High-performance Computing Centre (HPC, R5 million). The UFS’ HPC consists of approximately 900 computer cores (equal to 900 ordinary personal computers) encapsulated in one compact system handling calculations at a billion-datapoint level It is used to calculate the geometry and spatial arrangements, energy and characteristics of molecules. The bigger the molecule that is worked with, the more powerful the computers must be doing the calculations. Computing chemistry is particularly useful to calculate molecular characteristics in the absence of X-ray crystallographic or other structural information. Some reactions are so quick that the intermediary products cannot be characterised and computing chemistry is of invaluable value in that case.
  • Catalytic and high-pressure equipment (R6 million; some of the most advanced equipment in the world). The pressures reached (in comparison with those in car tyres) are in gases (100 times bigger) and in fluids (1 500 times) in order to study very special reactions. The research is undertaken, some of which are in collaboration with Sasol, to develop new petrol and petrol additives and add value to local chemicals.
  • Reaction speed equipment (Kinetics: R5 million; some of the most advanced equipment in the world). The tempo and reactions can be studied in the ultraviolet, visible and infrared area at millisecond level; if combined with the NMR, up to a microsecond level (one millionth of a second.

Typical reactions are, for example, the human respiratory system, the absorption of agents in the brain, decomposition of nanomaterials and protein, acid and basis polymerisation reactions (shaping of water-bottle plastic) and many more.

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