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18 May 2025 | Story André Damons | Photo André Damons
Research room
Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics explains how the PEA POD® infant body composition analyser works. Dr Balekile Mzangwa, CEO of Universitas Academic Hospital, and Dr Grace London, Chief Director: District Health services at the Free State Department of Health, listens in.

In a significant stride toward improving maternal and child health in the Free State, the Universitas Academic Hospital, in collaboration with the Faculty of Health Sciences at the University of the Free State (UFS), has launched an innovative Research Room which houses the PEA POD® infant body composition analyser and the Dual-Energy X-ray Absorptiometry (DXA) machine used to assess body composition and bone mineral density.

The initiative, which marks a new era in neonatal care and research, aims to integrate cutting-edge technology into routine clinical care. The PEA POD®, a non-invasive device that uses air displacement plethysmography, allows for precise measurement of fat and fat-free mass in newborns – offering a more accurate assessment of growth and nutritional status than traditional methods. 

The research room is a newly renovated and dedicated space adjacent to the maternity and neonatal units, ensuring quick, safe access to the newborns in the hospital. Two full-time MSc Dietetics students have been trained to perform the PEAPOD® assessments and colleagues from Radiography will perform the DXA assessments. This work lays the foundation for an ongoing maternal and infant body composition database –  a valuable resource for research, clinical care, and policy guidance.

Aligned with national health priorities

According to Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics, this initiative is the result of a multidisciplinary collaboration across Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics, to mention just a few of the collaborators. They are optimistic about the dual impact of this project as it advances academic and clinical research in early-life nutrition and growth as well as enhancing patient care at Universitas Hospital – bringing measurable benefits to mothers and their babies, she said. 

“This initiative is well aligned with national health priorities. According to the South African Early Childhood Review 2024, malnutrition in all its forms remains a significant challenge with short- and long-term consequences for mothers and their babies, especially during the first 1 000 days of life, from conception to the second birthday.

“We know from global and local evidence that growth patterns established during early life have profound and lasting effects on an individual’s health, development, and well-being. Our work at the University of the Free State has focused on the nutritional status of pregnant women and the early environments to which infants are exposed, both during and after pregnancy,” said Prof Walsh. 

However, she continued, in previous studies, they faced a significant challenge: the lack of specialised equipment to accurately measure infant body composition. Traditional measures such as weight and length provide only part of the picture.

 

New possibilities in healthcare, science, and service

Dr Mzangwa said the day not only marks the unveiling of state-of-the-art technology, but the beginning of a new chapter in how they will care for and understand the youngest and most vulnerable patients. The PEA POD® and DXA, which is now housed just steps away from the maternity and neonatal wards, symbolise a shared vision between the hospital and the Faculty of Health Sciences at the UFS: a vision grounded in evidence-based care, cutting-edge research, and above all, compassion.

“We express our sincere appreciation to everyone who supported this initiative. We also acknowledge the dedication of all the collaborating departments – Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics –  and thank Prof Corinna Walsh and Dr Lizzy Tabane for their leadership and insight.”

Prof Janse van Vuuren, said: “Today, we do more than open a physical space. We open the door to new possibilities in healthcare, science, and service to the people of our province. It is a shining example of what can be achieved when government and academia come together, united by a common purpose – to improve lives through knowledge, innovation, and care.”

The technologies that will be used in this facility are more than just advanced instruments, they are tools that allow medical staff to better understand the human body in its earliest and most vulnerable stages, as well as throughout the lifespan. With this understanding comes the ability to make informed decisions, to intervene earlier, and to tailor care in ways that truly meet the needs of our patients, said Prof Janse van Vuuren.

“This space is more than a research centre. It is a testament to our commitment to evidence-based care. It is a place where data meets compassion, where science serves humanity. The work that will happen here will not be confined to the walls of academia –  it has the potential to ripple outward into clinics, into hospitals, and into homes. It will shape guidelines, inform policy, and ultimately, improve outcomes for patients across our province and beyond.”


News Archive

Champagne and cancer have more in common than you might think
2013-05-08

 

Photo: Supplied
08 May 2013

No, a glass of champagne will not cure cancer....

…But they have more in common than you might think.

Researchers from the Departments of Microbial Biochemical and Food Biotechnology, Physics and the Centre for Microscopy at the University of the Free State in South Africa were recently exploring the properties of yeast cells in wine and food to find out more of how yeast was able to manufacture the gas that caused bread to rise, champagne to fizz and traditional beer to foam. And the discovery they made is a breakthrough that may have enormous implications for the treatment of diseases in humans.

The team discovered that they could slice open cells with argon gas particles, and look inside. They were surprised to find a maze of tiny passages like gas chambers that allowed each cell to ‘breathe.’ It is this tiny set of ‘lungs’ that puts the bubbles in your bubbly and the bounce in your bread.

But it was the technique that the researchers used to open up the cells that caught the attention of the scientists at the Mayo Clinic (Tumor Angiogenesis and Vascular Biology Research Centre) in the US.

Using this technology, they ultimately aim to peer inside cells taken from a cancer patient to see how treatment was progressing. In this way they would be able to assist the Mayo team to target treatments more effectively, reduce dosages in order to make treatment gentler on the patient, and have an accurate view of how the cancer was being eliminated.

“Yes, we are working with the Mayo Clinic,” said Profes Lodewyk Kock from the Microbial, Biochemical and Food Biotechnology Department at the UFS.

“This technique we developed has enormous potential for cell research, whether it is for cancer treatment or any other investigation into the working of cells. Through nanotechnology, and our own invention called Auger-architectomics, we are able to see where no-one has been able to see before.”

The team of Prof Kock including Dr Chantel Swart, Kumisho Dithebe, Prof Hendrik Swart (Physics, UFS) and Prof Pieter van Wyk (Centre for Microscopy, UFS) unlocked the ‘missing link’ that explains the existence of bubbles inside yeasts, and incidentally have created a possible technique for tracking drug and chemotherapy treatment in human cells.

Their work has been published recently in FEMS Yeast Research, the leading international journal on yeast research. In addition, their discovery has been selected for display on the cover page of all 2013 issues of this journal.

One can most certainly raise a glass of champagne to celebrate that!

There are links for video lectures on the technique used and findings on the Internet at:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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