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18 May 2025 | Story André Damons | Photo André Damons
Research room
Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics explains how the PEA POD® infant body composition analyser works. Dr Balekile Mzangwa, CEO of Universitas Academic Hospital, and Dr Grace London, Chief Director: District Health services at the Free State Department of Health, listens in.

In a significant stride toward improving maternal and child health in the Free State, the Universitas Academic Hospital, in collaboration with the Faculty of Health Sciences at the University of the Free State (UFS), has launched an innovative Research Room which houses the PEA POD® infant body composition analyser and the Dual-Energy X-ray Absorptiometry (DXA) machine used to assess body composition and bone mineral density.

The initiative, which marks a new era in neonatal care and research, aims to integrate cutting-edge technology into routine clinical care. The PEA POD®, a non-invasive device that uses air displacement plethysmography, allows for precise measurement of fat and fat-free mass in newborns – offering a more accurate assessment of growth and nutritional status than traditional methods. 

The research room is a newly renovated and dedicated space adjacent to the maternity and neonatal units, ensuring quick, safe access to the newborns in the hospital. Two full-time MSc Dietetics students have been trained to perform the PEAPOD® assessments and colleagues from Radiography will perform the DXA assessments. This work lays the foundation for an ongoing maternal and infant body composition database –  a valuable resource for research, clinical care, and policy guidance.

Aligned with national health priorities

According to Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics, this initiative is the result of a multidisciplinary collaboration across Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics, to mention just a few of the collaborators. They are optimistic about the dual impact of this project as it advances academic and clinical research in early-life nutrition and growth as well as enhancing patient care at Universitas Hospital – bringing measurable benefits to mothers and their babies, she said. 

“This initiative is well aligned with national health priorities. According to the South African Early Childhood Review 2024, malnutrition in all its forms remains a significant challenge with short- and long-term consequences for mothers and their babies, especially during the first 1 000 days of life, from conception to the second birthday.

“We know from global and local evidence that growth patterns established during early life have profound and lasting effects on an individual’s health, development, and well-being. Our work at the University of the Free State has focused on the nutritional status of pregnant women and the early environments to which infants are exposed, both during and after pregnancy,” said Prof Walsh. 

However, she continued, in previous studies, they faced a significant challenge: the lack of specialised equipment to accurately measure infant body composition. Traditional measures such as weight and length provide only part of the picture.

 

New possibilities in healthcare, science, and service

Dr Mzangwa said the day not only marks the unveiling of state-of-the-art technology, but the beginning of a new chapter in how they will care for and understand the youngest and most vulnerable patients. The PEA POD® and DXA, which is now housed just steps away from the maternity and neonatal wards, symbolise a shared vision between the hospital and the Faculty of Health Sciences at the UFS: a vision grounded in evidence-based care, cutting-edge research, and above all, compassion.

“We express our sincere appreciation to everyone who supported this initiative. We also acknowledge the dedication of all the collaborating departments – Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics –  and thank Prof Corinna Walsh and Dr Lizzy Tabane for their leadership and insight.”

Prof Janse van Vuuren, said: “Today, we do more than open a physical space. We open the door to new possibilities in healthcare, science, and service to the people of our province. It is a shining example of what can be achieved when government and academia come together, united by a common purpose – to improve lives through knowledge, innovation, and care.”

The technologies that will be used in this facility are more than just advanced instruments, they are tools that allow medical staff to better understand the human body in its earliest and most vulnerable stages, as well as throughout the lifespan. With this understanding comes the ability to make informed decisions, to intervene earlier, and to tailor care in ways that truly meet the needs of our patients, said Prof Janse van Vuuren.

“This space is more than a research centre. It is a testament to our commitment to evidence-based care. It is a place where data meets compassion, where science serves humanity. The work that will happen here will not be confined to the walls of academia –  it has the potential to ripple outward into clinics, into hospitals, and into homes. It will shape guidelines, inform policy, and ultimately, improve outcomes for patients across our province and beyond.”


News Archive

Researcher part of project aimed at producing third-generation biofuels from microalgae in Germany
2016-05-09

Description: Novagreen bioreactor  Tags: Novagreen bioreactor

Some of the researchers and technicians among the tubes of the Novagreen bioreactor (Prof Grobbelaar on left)

A researcher from the University of the Free State (UFS), Prof Johan Grobbelaar, was invited to join a group of scientists recently at the Institute for Bio- and Geo-Sciences of the Research Centre Jülich, in Germany, where microalgae are used for lipid (oil) production, and then converted to kerosene for the aviation industry.

The project is probably the first of its kind to address bio-fuel production from microalgae on such a large scale.  

“The potential of algae as a fuel source is undisputed, because it was these photoautotrophic micro-organisms that were fixing sunlight energy into lipids for millions of years, generating the petroleum reserves that modern human civilisation uses today.  However, these reserves are finite, so the challenge is marrying biology with technology to produce economically-competitive fuels without harming the environment and compromising our food security.  The fundamental ability that microalgae have to produce energy-rich biomass from CO2, nutrients, and sunlight through photosynthesis for biofuels, is commonly referred to as the Third-Generation Biofuels (3G),” said Prof Grobbelaar.

The key compounds used for bio-diesel and kerosene production are the lipids and, more particularly, the triacylglyserols commonly referred to as TAGs.  These lipids, once extracted, need to be trans-esterified for biodiesel, while a further “cracking” step is required to produce kerosene.  Microalgae can store energy as lipids and/or carbohydrates. However, for biofuels, microalgae with high TAG contents are required.  A number of such algae have been isolated, and lipid contents of up to 60% have been achieved.

According to Prof Grobbelaar, the challenge is large-scale, high-volume production, since it is easy to manipulate growth conditions in the laboratory for experimental purposes.  

The AUFWIND project (AUFWIND, a German term for up-current, or new impetus) in Germany consists of three different commercially-available photobioreactor types, which are being compared for lipid production.

Description: Lipid rich chlorella Tags: Lipid rich chlorella

Manipulated Chlorella with high lipid contents (yellow) in the Novagreen bioreactor

The photobioreactors each occupies 500 m2 of land surface area, are situated next to one another, and can be monitored continuously.  The three systems are from Novagreen, IGV, and Phytolutions.  The Novagreen photobioreactor is housed in a glass house, and consist of interconnected vertical plastic tubes roughly 150 mm in diameter. The Phytolutions system is outdoors, and consists of curtains of vertical plastic tubes with a diameter of about 90 mm.  The most ambitious photobioreactor is from IGV, and consists of horizontally-layered nets housed in a plastic growth hall, where the algae are sprayed over the nets, and allowed to grow while dripping from one net to the next.

Prof Grobbelaar’s main task was to manipulate growth conditions in such a way that the microalgae converted their stored energy into lipids, and to establish protocols to run the various photobioreactors. This was accomplished in just over two months of intensive experimentation, and included modifications to the designs of the photobioreactors, the microalgal strain selection, and the replacement of the nutrient broth with a so-called balanced one.

Prof Grobbelaar has no illusions regarding the economic feasibility of the project.  However, with continued research, optimisation, and utilisation of waste resources, it is highly likely that the first long-haul flights using microalgal-derived kerosene will be possible in the not-too-distant future.

Prof Grobbelaar from the Department of Plant Sciences, although partly retired, still serves on the editorial boards of several journals. He is also involved with the examining of PhDs, many of them from abroad.  In addition, he assisted the Technology Innovation Agency of South Africa in the formulation of an algae-biotechnology and training centre.  “The chances are good that such a centre will be established in Upington, in the Northern Cape,” Prof Grobbelaar said.

 

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