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18 May 2025 | Story André Damons | Photo André Damons
Research room
Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics explains how the PEA POD® infant body composition analyser works. Dr Balekile Mzangwa, CEO of Universitas Academic Hospital, and Dr Grace London, Chief Director: District Health services at the Free State Department of Health, listens in.

In a significant stride toward improving maternal and child health in the Free State, the Universitas Academic Hospital, in collaboration with the Faculty of Health Sciences at the University of the Free State (UFS), has launched an innovative Research Room which houses the PEA POD® infant body composition analyser and the Dual-Energy X-ray Absorptiometry (DXA) machine used to assess body composition and bone mineral density.

The initiative, which marks a new era in neonatal care and research, aims to integrate cutting-edge technology into routine clinical care. The PEA POD®, a non-invasive device that uses air displacement plethysmography, allows for precise measurement of fat and fat-free mass in newborns – offering a more accurate assessment of growth and nutritional status than traditional methods. 

The research room is a newly renovated and dedicated space adjacent to the maternity and neonatal units, ensuring quick, safe access to the newborns in the hospital. Two full-time MSc Dietetics students have been trained to perform the PEAPOD® assessments and colleagues from Radiography will perform the DXA assessments. This work lays the foundation for an ongoing maternal and infant body composition database –  a valuable resource for research, clinical care, and policy guidance.

Aligned with national health priorities

According to Prof Corinna Walsh from the UFS Department of Nutrition and Dietetics, this initiative is the result of a multidisciplinary collaboration across Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics, to mention just a few of the collaborators. They are optimistic about the dual impact of this project as it advances academic and clinical research in early-life nutrition and growth as well as enhancing patient care at Universitas Hospital – bringing measurable benefits to mothers and their babies, she said. 

“This initiative is well aligned with national health priorities. According to the South African Early Childhood Review 2024, malnutrition in all its forms remains a significant challenge with short- and long-term consequences for mothers and their babies, especially during the first 1 000 days of life, from conception to the second birthday.

“We know from global and local evidence that growth patterns established during early life have profound and lasting effects on an individual’s health, development, and well-being. Our work at the University of the Free State has focused on the nutritional status of pregnant women and the early environments to which infants are exposed, both during and after pregnancy,” said Prof Walsh. 

However, she continued, in previous studies, they faced a significant challenge: the lack of specialised equipment to accurately measure infant body composition. Traditional measures such as weight and length provide only part of the picture.

 

New possibilities in healthcare, science, and service

Dr Mzangwa said the day not only marks the unveiling of state-of-the-art technology, but the beginning of a new chapter in how they will care for and understand the youngest and most vulnerable patients. The PEA POD® and DXA, which is now housed just steps away from the maternity and neonatal wards, symbolise a shared vision between the hospital and the Faculty of Health Sciences at the UFS: a vision grounded in evidence-based care, cutting-edge research, and above all, compassion.

“We express our sincere appreciation to everyone who supported this initiative. We also acknowledge the dedication of all the collaborating departments – Paediatrics and Child Health, Obstetrics and Gynaecology, Radiography, Nutrition and Dietetics –  and thank Prof Corinna Walsh and Dr Lizzy Tabane for their leadership and insight.”

Prof Janse van Vuuren, said: “Today, we do more than open a physical space. We open the door to new possibilities in healthcare, science, and service to the people of our province. It is a shining example of what can be achieved when government and academia come together, united by a common purpose – to improve lives through knowledge, innovation, and care.”

The technologies that will be used in this facility are more than just advanced instruments, they are tools that allow medical staff to better understand the human body in its earliest and most vulnerable stages, as well as throughout the lifespan. With this understanding comes the ability to make informed decisions, to intervene earlier, and to tailor care in ways that truly meet the needs of our patients, said Prof Janse van Vuuren.

“This space is more than a research centre. It is a testament to our commitment to evidence-based care. It is a place where data meets compassion, where science serves humanity. The work that will happen here will not be confined to the walls of academia –  it has the potential to ripple outward into clinics, into hospitals, and into homes. It will shape guidelines, inform policy, and ultimately, improve outcomes for patients across our province and beyond.”


News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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