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13 May 2025 | Story André Damons | Photo Supplied
Prof Martin Nyaga
Prof Martin Nyaga, Full Professor in the Division of Virology and Head of the Next Generation Sequencing Unit (UFS-NGS Unit) at the University of the Free State.

Prof Martin Nyaga, an NRF B-Rated Full Professor in the Division of Virology and Head of the Next Generation Sequencing (UFS-NGS) Unit at the University of the Free State (UFS), has been selected as one of the cohort II fellows of the prestigious Calestous Juma Science Leadership Fellowship

Prof Nyaga, who is one of 12 individuals from six African countries (Ethiopia, Ghana, Kenya, Malawi, South Africa, and Zambia) selected to this cohort, says he is profoundly honoured. Through the prestigious fellowship, inspired by Professor Juma’s visionary legacy, he envisions advancing Africa’s capacity to combat infectious diseases by developing robust, mNGS-based surveillance systems that detect and characterise emerging pathogens early enough.

“The opportunity to join a cohort of exceptional African scientists, united by a shared commitment to addressing global health challenges, is both humbling and inspiring. I feel a deep sense of responsibility to uphold the fellowship’s mission of fostering sustainable development through cutting-edge research and policy engagement, particularly in the context of my work on genomic disease surveillance. 

“I am deeply inspired by Professor Calestous Juma’s legacy of harnessing science for sustainable development, and I am committed to embodying his optimism and interdisciplinary approach. The fellowship represents a transformative platform to advance scientific innovation and leadership in Africa. I would like to extend my gratitude to the Gates Foundation for this opportunity, and I look forward to contributing to a transformative era of African scientific leadership,” says Prof Nyaga.

 

Advantages of the Fellowship

The Calestous Juma Science Leadership Fellowship focuses on bringing together accomplished innovators to form a community of global health opinion shapers and influencers. The programme provides targeted professional development to support fellows as they expand their networks, amplify their voices, and continue to build and strengthen a dynamic, resilient research & development (R&D) ecosystem that changes the lives of people living not only in Africa but around the world.

Among the new cohort are experts in virology (including HIV and rota), bacteriology (including TB and strep), immunology, malaria, modelling, maternal immunisation, epidemiology, chemistry, drug discovery and development, vaccine discovery, clinical trials, and controlled human infection models to name just a few examples. 

According to Prof Nyaga, Director of a WHO Collaborating Centre for Vaccine Preventable Diseases (VPD) Surveillance and Pathogen Genomics, selection for the Fellowship is a rigorous and competitive process, designed to identify African scientists with exceptional research portfolios and leadership potential. Candidates are typically invited based on their established track record in transformative science, as well as their ability to anchor health and R&D initiatives within their communities. Successful applicants are evaluated for their scientific excellence, interdisciplinary networks, and commitment to mentoring the next generation of African scientists, aligning with the fellowship’s holistic view of leadership.

The NRF B3-rated scientist says he is eager to engage with the fellowship’s vibrant community of scientists from multiple African countries, fostering collaborations that amplify our collective impact on global health. He anticipates benefiting from the fellowship’s non-scientific training in communication, policy engagement, and institution strengthening. Participating in networking opportunities will broaden his perspectives and strengthen his capacity to drive innovative solutions in Africa’s genomic R&D ecosystem.

“I believe my work in pathogen surveillance research using genomics, aligns closely with the fellowship's objectives. As a fellow, I bring a wealth of experience in leading multi-country projects, establishing regional collaborations, and fostering capacity development through training and mentorship. 

“In addition, my ongoing work at the UFS-NGS Unit, including projects on enteric and respiratory virus surveillance, vaccine monitoring and efficacy using next generation sequencing, which will enrich discussions on public health. Conversely, the fellowship will enhance my scientific development by providing advanced training in leadership and policy advocacy, enabling me to translate research findings into actionable health policies. This synergy will elevate my capacity to lead transformative R&D initiatives and mentor future African scientists.” 

 

Contributing to the betterment of people 

Prof Nyaga believes his research on vaccine efficacy and metagenomics of gut and respiratory virome will contribute to the betterment of not only Africans, but also people around the world by informing targeted interventions in vaccine efficacy monitoring and development. This research will also contribute to the reduction of morbidity and mortality applicable to enteric and respiratory infections in vulnerable populations. 

Furthermore, he explains, the fellowship’s emphasis on networking and policy engagement will amplify these efforts, enabling him to advocate for evidence-based health policies across Africa. Globally, their collective work as Calestous Juma Science Leadership fellows will strengthen the R&D ecosystem, fostering innovation that addresses pandemic preparedness and other health challenges. By building resilient scientific communities, the fellowship will contribute to sustainable development, improving lives in Africa and beyond.

News Archive

Early diagnosis of hearing loss is important
2017-09-11

  Description: Magteld small Tags: birth defects, hearing loss, Dr Magteld Smith, Department of Otorhinolaryngology

Dr Magteld Smith, lecturer in the
Department of Otorhinolaryngology
at the University of the Free State (UFS)
Photo: Supplied


One of the most common, misunderstood and neglected birth defects in developing countries is hearing loss, which can most severely impair and have a dramatic impact of the quality of life the of the person with hearing loss. 

This is according to Dr Magteld Smith, lecturer in the Department of Otorhinolaryngology at the University of the Free State (UFS). 

“Hearing loss refers to all the different types and levels of hearing loss, from slight to profound hearing loss,” she said. 

Derived from a number of retrospective studies in South Africa, it was found 17 people a day are born with hearing loss. More than 95% of those children are born to hearing parents. This estimate excludes children and adults who lost their hearing after birth. 

According to Dr Smith, hearing loss strikes at the very essence of being human, because it hinders communication with others. To enable people to communicate with those with hearing loss, the university’s Department of South African Sign Language teaches students sign language. This year, the department enrolled 230 students. A number of these students are from the Faculty of Education. These students could from 2017 for the first time choose sign language as a subject.

“Studies have shown that important language skills are learned before the age of three because hearing and learning language are closely tied together. Brain development of the auditory pathways and language cortex is occurring in young children as they respond to auditory and visual language. In families that are part of deaf culture, these parents automatically sign from day one, so the baby is learning visual (sign) language, and the appropriate brain development is occurring.

Beskrywing: Doof readmore Sleutelwoorde: geboorte-afwykings, gehoorverlies, dr Magteld Smith, Departement Otorinolaringologie

About 230 students are enrolled for the subject, South African 
Sign Language, at the UFS. As an assignment some of the students 
were asked to design posters to create deaf awareness among 
others on campus. From the left are: Poleliso Mpahane, 
Masajin Koalepe, Ntshitsa Mosase, and Zoleka Ncamane. 
Photo: Leonie Bolleurs

“However, if a child has an undiagnosed hearing loss and the parents are unaware, the child will not receive the needed language stimulation — and the hoped-for development won’t take place. It is critical to understand that children with hearing loss have their own talents, different levels of intelligence, socioeconomic circumstances and different abilities, just like hearing children. Therefore, one size does not fit all,” Dr Smith said. 

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