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16 May 2025 | Story André Damons | Photo Supplied
Prof Wynand Goosen
Prof Wynand Goosen, Professor and Lead for One Health in the Department of Microbiology and Biochemistry at the University of the Free State was nominated in the TW Kambule-NSTF Award: Researcher category of the 2024/25 NSTF-South32 Awards.

Being nominated for a ‘Science Oscar’ is exciting and validates nominees’ efforts, particularly in a field as challenging and essential as infectious diseases, for which they are recognised at the highest level. 

This is according to Prof Wynand Goosen, Professor and Lead for One Health in the Department of Microbiology and Biochemistry at the University of the Free State (UFS). He was nominated in the TW Kambule-NSTF Award: Researcher category of the 2024/25 NSTF-South32 Awards for his landmark discovery of Mycobacterium bovis infection in humans in South Africa – the first confirmed cases in the country. 

Prof Goosen, who previously won the NSTF-South32 Emerging Researcher Award, says the nomination is a powerful affirmation of the impact that focused, interdisciplinary research can have. It reflects not only his personal commitment but also the dedication of a talented and hard-working team. “I am honoured and humbled to be nominated. It is also a testament to the support and vision of UFS, particularly as we position ourselves as leaders in One Health research in South Africa,” he says. 

 

Focus of research 

He was nominated by Prof Vasu Reddy, UFS Deputy Vice-Chancellor: Research and Internationalisation, and Prof Paul Oberholster, Dean for the Faculty of Natural and Agricultural Sciences (NAS) at the UFS, and Prof Nico Gey van Pittius and Prof Elmi Muller from Stellenbosch University (US). The NSTF Awards, known as the ‘Science Oscars’of SA, honour, reward, celebrate, profile and promote outstanding contributions to science, engineering and technology (SET) and innovation in South Africa.

“The nomination,” Prof Goosen continues, “recognises our work in the field of zoonotic tuberculosis (TB) and other emerging infectious diseases at the human-animal-environment interface. Our research focuses on the molecular detection and characterisation of pathogenic mycobacteria in wildlife, livestock, and human populations, with the aim of informing better surveillance, diagnostics, and control strategies — particularly in high-risk ecosystems. This includes novel applications in wildlife TB surveillance and understanding the transmission dynamics between animals and people.”

 

Establishing a Kovsie One Health Research Unit

This research is critically important as South Africa continues to face a high burden of tuberculosis, including zoonotic TB, which often goes under-detected in rural and wildlife-rich areas. Understanding how these pathogens circulate between humans, animals, and the environment, explains Prof Goosen, is essential for effective disease control and to mitigate future pandemics. This work directly supports national health priorities, informs policy, and contributes to global strategies for One Health.

Prof Goosen and the team are in the process of laying the groundwork for the establishment of a Kovsie One Health Research Unit, which will serve as a collaborative platform for research spanning human, animal, and environmental health. One of their key projects involves expanding TB and AMR surveillance in wildlife-livestock-human interfaces, using cutting-edge diagnostics and genomic tools. They are also initiating partnerships with industry and international institutions to address emerging zoonoses and environmental pathogens in a transdisciplinary manner.

News Archive

Plant scientists address wheat rust diseases at SASPP congress
2015-02-02

Pictured from the left are: Prof Zakkie Pretorius, Dr Botma Visser and Howard Castelyn.
Photo: Supplied

In his research, Dr Botma Visser, researcher in the Department of Plant Sciences at the University of the Free State, highlighted the population dynamics of the stem rust fungus (Puccinia graminis f. sp. tritici) in Southern Africa. In recent years, two foreign stem rust races were introduced to South Africa, and a local virulence adaptation occurred in a third.

All of these races form part of the Ug99 group, a highly virulent collection of rust races endangering wheat production in many parts of the world. Despite the fact that half of the members of the Ug99 race group is prevalent in South Africa, Dr Visser’s work has clearly shown that Ug99 did not have its origin here. This emphasised the need to include neighbouring countries in the annual stem rust surveys, to proactively identify new races that could threaten local wheat production. In his research, Dr Visser also mentioned the way in which he has optimised modern molecular tools to accurately detect Ug99 isolates.

Dr Visser is one of three scientists from the Department of Plant Sciences that addressed delegates attending the biennial congress of the Southern African Society for Plant Pathology (SASPP) on the Bloemfontein Campus earlier this month on progress regarding research on wheat rust diseases conducted at the UFS.

Howard Castelyn, a PhD student in Plant Sciences, presented his research on quantifying fungal growth of the stem rust pathogen in wheat varieties displaying genetic resistance. This resistance, which is best expressed in adult plants, has the potential to remain durable in the presence of new rust variants. His presentation at the congress focused on optimising microscopic and molecular techniques to track fungal development in stem tissues of adult plants. These results now allow scientists to link rust infection levels and cellular responses with particular resistance genes expressed by the wheat plant, and contributing to the understanding and exploitation of durable resistance.

Prof Zakkie Pretorius presented his research, explaining how new genetic diversity for resistance to the stripe (yellow) rust fungus (Puccinia striiformis) is discovered, analysed and applied in South Africa. This research, conducted in collaboration with Dr Renée Prins and her team at CenGen, is unravelling the genetic basis of stripe rust resistance in a promising wheat line identified by Dr Willem Boshoff, a plant breeder at Pannar. The line and DNA markers to track the resistance genes will soon be introduced to South African wheat breeding programmes.

The rust research programme at the UFS contributes significantly to the successful control of these important crop diseases.

In addition to the contributions by the UFS, rust fungi featured prominently at the SASPP, with first reports of new diseases on sugar cane and Acacia and Eucalyptus trees in South Africa. A case study of the use of a rust fungus as a biological control agent for invasive plant species in the Western Cape, was also presented.

 

For more information or enquiries contact news@ufs.ac.za .

 

 

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