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3MT crowns its 2025 PhD national competition winner

28 October 2025 | Story Andile Mbowana | Photo Supplied

PhD candidates at the 2025 National 3MT Competition, hosted at the University of the Free State.

The University of the Free State Centre for Graduate Support (CGS) hosted the 2025 National Three-Minute Thesis (3MT) Competition on 24 October in the Albert Wessels Auditorium, bringing together some of South Africa’s brightest PhD minds under one roof. The annual event, which has become a highlight on the national academic calendar, challenges doctoral candidates from universities across the country to present their complex research in just three minutes, using language accessible to a non-specialist audience.

This year’s competition drew impressive presentations from top scholars representing various disciplines – from health sciences and agriculture to humanities – all showcasing the depth and diversity of South Africa’s research landscape.

Delivering the keynote address, Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation at the UFS, reflected on The Essence of Postgraduate Studies and Success in South Africa. He emphasised that postgraduate research plays a critical role in shaping innovation and addressing the country’s most pressing challenges. “As postgraduates, you represent a powerful tool of transformation, equity, and innovation, and every thesis is a story of resilience and a long journey of research,” he said. Prof Reddy also talked about how “competitions like the 3MT not only celebrate research excellence but also teach scholars how to communicate their ideas to inspire real-world impact,” praising the competition for opening opportunities for postgraduate scholars.

The University of the Free State was represented by two candidates, Rentia du Plessis from the Faculty of The Humanities, who presented her 3MT title, Exploring Instructional Communication Strategic for Holistic Student Development, and Naquita Fernandes from the Faculty of Economic and Management Sciences, with her 3MT title, Triggering Online Review Generation Behaviour.

Other universities, such as the Nelson Mandela University, Unisa, the University of KwaZulu-Natal, the University of the Western Cape, the University of Johannesburg, and the University of Pretoria, were also present.

After a series of captivating presentations, Robinah Nakawunde from Stellenbosch University claimed the top prize. Representing the Faculty of Medicine and Health Sciences, her presentation titled, Cured but Not Healed: Uncovering the Lung’s Struggles after TB, captured the attention of both the judges and the audience. Her research sheds light on how pulmonary tuberculosis continues to affect lung function even after successful treatment, highlighting the need for improved post-TB health-care interventions.

The first runner-up position went to Aaron Harvey from the University of Pretoria’s Faculty of Natural and Agricultural Sciences, whose research explores how avocado plants fight root rot disease using RNA interference mechanisms. His presentation, titled How Avocado Cells Fight Against the Root Rot Disease Caused by Phytophthora cinnamomi, Using RNAi Gatekeepers, impressed the judges with its clarity and scientific depth.

Morgan Lee from the University of Cape Town’s Faculty of Humanities took home the second runner-up prize. Her presentation, Locked In: The Hidden Barriers to Sustainable Agriculture, tackled the challenges facing South Africa’s commercial grain sector in transitioning towards more sustainable practices, offering insights that bridge environmental and social considerations.

The 2025 3MT National Competition once again demonstrated the power of concise, impactful communication in research. As the curtain closed, it was evident that South Africa’s future of research and innovation remains in capable hands, ones that can not only investigate deeply, but also explain passionately

News Archive

#Women'sMonth: Save the children

2017-08-10

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach
When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.”

A future without rotavirus vaccination?
Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said.

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