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09 September 2025 | Story Martinette Brits | Photo Stephen Collett
Prof Botma Visser
Prof Botma Visser delivered his inaugural lecture at the University of the Free State, highlighting nearly two decades of research on wheat rust and global food security.

Safeguarding one of the world’s most vital staple foods was at the heart of the inaugural lecture delivered by Prof Botma Visser, Professor in the Department of Plant Sciences at the University of the Free State (UFS), on Wednesday 3 September 2025. Prof Visser shared insights from nearly two decades of research into wheat rust – a devastating crop disease that threatens both South Africa’s harvests and global food security.

“Wheat production in South Africa is threatened by three fungal pathogens that cause rust disease on the crop. Understanding the factors that contribute to virulence on locally grown cultivars is crucial to ensure continued wheat production,” said Prof Visser.

 

The fight against evolving wheat rusts

For the past 17 years, Prof Visser’s research has focused on the genetic structure of rust populations and the risks they pose to food security. His work has shown that these populations are dynamic and constantly changing due to genetic mutations within existing races, as well as the introduction of new races into South Africa.

“Computer modelling showed that rust can spread over vast distances by prevailing winds. During the 20th Century, at least four Southern African stem rust races managed to move across the Indian Ocean from Southern Africa to Australia. South Africa, in turn, received multiple new races from mid-Africa across Zambia and Zimbabwe, without any means of stopping these introductions,” he explained.

To respond to this challenge, his team recently implemented MARPLE (Mobile And Real-time Plant disEase) diagnostics using fourth-generation nanopore sequencing technology. This approach allows the rapid characterisation of fungal isolates, specifically targeting genes linked to fungicide resistance and virulence.

“This work,” Prof Visser noted, “is part of an effort to safeguard global wheat production.”

His research is a collaborative effort with Prof Willem Boshoff (Department of Plant Sciences, UFS) and Dr Tarekegn Terefe (Agricultural Research Council – Small Grain, Bethlehem). Together, their work has positioned the UFS as an internationally recognised centre of excellence in wheat rust research.

 

About Prof Botma Visser

Prof Botma Visser obtained his BSc in Botany and Microbiology (1988), BSc Honours in Microbiology (1989), and MSc in Botany (1993) at the University of the Free State, where he also completed his PhD in Botany in 2004.

His career spans more than 18 years of research into wheat rust pathogens, combining annual surveys, race pathotyping, molecular genetics, and cutting-edge sequencing technologies. His expertise has not only advanced understanding of rust population dynamics in South Africa but also contributed to global collaborative studies on crop disease.

News Archive

UFS responds to revocation of the accreditation of the SA Doping Control Laboratory by WADA
2017-07-01

The World Anti-Doping Agency (WADA) yesterday informed the South African Doping Control Laboratory (SADoCoL) at the University of the Free State (UFS) that the WADA accreditation status of the laboratory has been revoked.

This revocation does, however, not include the analysis of blood samples for the Athlete Biological Passport for which SADoCoL has been re-accredited in August 2016 and which the laboratory will continue to perform. It also does not impact at all on the testing of urine sport samples by the South African Institute of Drug-free Sport (SAIDS), who will continue to send such samples for testing to other WADA accredited laboratories, while blood samples will be tested at SADoCoL as before.

The revocation follows a year long period of suspension in which the laboratory had to develop its analytical capabilities and instate new systems and methodologies.  “In this period the laboratory worked diligently to realize all of these requirements and according to an inspection team from the WADA Laboratory Expert Group who visited the laboratory in February 2017, much has been done and the Laboratory is in a much better state than it was before the suspension in May 2016,” says prof Marthinus van der Merwe, Director of SADoCoL.

“However, there were certain aspects of these requirements that the laboratory could not achieve within the time-frame stipulated by WADA and therefore the organisation is bound by its rules and regulations to now revoke the accreditation status of the laboratory. Since much effort and resources have been invested in the laboratory in the last two years, the management of SADoCoL together with senior leadership of the UFS decided to go ahead and finalise all development in order to re-apply for WADA accreditation,” says prof van der Merwe. 

“The UFS fully acknowledges the hard work of SADoCoL during the period of development and is committed to support the laboratory in its endeavors to re-attain its status within the very specialised and highly regulated community of world-wide doping control laboratories.  The premium goal of the laboratory is still to fully serve the sporting community of South Africa and Africa according to the WADA guidelines for anti-doping control in Sport and it is confident to attain that with the support of all role players in this field,” says Prof Witthuhn, Vice-Rector: Research at the UFS.

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