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09 September 2025 | Story Martinette Brits | Photo Stephen Collett
Prof Botma Visser
Prof Botma Visser delivered his inaugural lecture at the University of the Free State, highlighting nearly two decades of research on wheat rust and global food security.

Safeguarding one of the world’s most vital staple foods was at the heart of the inaugural lecture delivered by Prof Botma Visser, Professor in the Department of Plant Sciences at the University of the Free State (UFS), on Wednesday 3 September 2025. Prof Visser shared insights from nearly two decades of research into wheat rust – a devastating crop disease that threatens both South Africa’s harvests and global food security.

“Wheat production in South Africa is threatened by three fungal pathogens that cause rust disease on the crop. Understanding the factors that contribute to virulence on locally grown cultivars is crucial to ensure continued wheat production,” said Prof Visser.

 

The fight against evolving wheat rusts

For the past 17 years, Prof Visser’s research has focused on the genetic structure of rust populations and the risks they pose to food security. His work has shown that these populations are dynamic and constantly changing due to genetic mutations within existing races, as well as the introduction of new races into South Africa.

“Computer modelling showed that rust can spread over vast distances by prevailing winds. During the 20th Century, at least four Southern African stem rust races managed to move across the Indian Ocean from Southern Africa to Australia. South Africa, in turn, received multiple new races from mid-Africa across Zambia and Zimbabwe, without any means of stopping these introductions,” he explained.

To respond to this challenge, his team recently implemented MARPLE (Mobile And Real-time Plant disEase) diagnostics using fourth-generation nanopore sequencing technology. This approach allows the rapid characterisation of fungal isolates, specifically targeting genes linked to fungicide resistance and virulence.

“This work,” Prof Visser noted, “is part of an effort to safeguard global wheat production.”

His research is a collaborative effort with Prof Willem Boshoff (Department of Plant Sciences, UFS) and Dr Tarekegn Terefe (Agricultural Research Council – Small Grain, Bethlehem). Together, their work has positioned the UFS as an internationally recognised centre of excellence in wheat rust research.

 

About Prof Botma Visser

Prof Botma Visser obtained his BSc in Botany and Microbiology (1988), BSc Honours in Microbiology (1989), and MSc in Botany (1993) at the University of the Free State, where he also completed his PhD in Botany in 2004.

His career spans more than 18 years of research into wheat rust pathogens, combining annual surveys, race pathotyping, molecular genetics, and cutting-edge sequencing technologies. His expertise has not only advanced understanding of rust population dynamics in South Africa but also contributed to global collaborative studies on crop disease.

News Archive

Plant scientist, Prof Zakkie Pretorius, contributes to food security with his research
2014-08-26

 
Many plant pathologists spend entire careers trying to outwit microbes, in particular those that cause diseases of economically important plants. In some cases control measures are simple and successful. In others, disease management remains an ongoing battle. 

Prof Zakkie Pretorius, Professor in the Department of Plant Sciences, works on a group of wheat diseases known as rusts. The name is derived from the powdery and brown appearance of these fungi.

Over the course of history wheat rusts have undergone what are notoriously known as boom and bust cycles. During boom periods the disease is controlled by means of heritable resistance in a variety, resulting in good yields. This resistance, though, is more often than not busted by the appearance of new rust strains with novel parasitic abilities. For resistance to remain durable, complex combinations of effective genes and chromosome regions have to be added in a single wheat variety.

In recent years, Prof Pretorius has focused on identifying and characterising resistance sources that have the potential to endure the onslaught of new rust races. His group has made great progress in the control of stripe rust – where several chromosome regions conditioning effective resistance have been identified.

Dr Renée Prins of CenGen and an affiliated UFS staff member, developed molecular markers for these resistance sources. These are now routinely applied in wheat breeding programmes in South Africa. In addition, Prof Pretorius collaborates with several countries to transfer newly discovered stem rust resistance genes to wheat, and in characterising effective sources of resistance in existing wheat collections.

His work is closely supported by research conducted by UFS colleagues, students and other partners on the genetics of the various wheat rust pathogens. These studies aim to answer questions about:
• the origin and relatedness of rust races,
• their highly successful parasitic ability, and
• their adaptation in different environments.

The UFS wheat rust programme adds significantly to the development of resistant varieties and thus more sustainable production of this important crop. 

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