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05 September 2025 | Story Kagiso Ngake and Dr Nitha Ramnath | Photo Stephen Collett
Consulate
Left: Stephanie Bruce, Consul General of the United States in South Africa Right: Prof Hester C. Klopper, Vice-Chancellor and Principal of the University of the Free State

The University of the Free State (UFS) recently had the honour of hosting Stephanie Bunce, Consul General of the United States (US) in South Africa, and her delegation on the Bloemfontein Campus. The visit came at a significant moment, shortly after the first 100 days of Prof Hester C. Klopper’s tenure as Vice-Chancellor and Principal. 

The meeting marked an important introduction between two leaders new in their respective roles: Prof Klopper at the UFS, and Consul General Bunce, who began her posting in Johannesburg in September 2024. Their discussions offered an opportunity to align the strategic ambitions of the UFS with the priorities of the U.S Mission in South Africa, while reflecting on the longstanding and fruitful relationship between the UFS and American universities. 

Consul General Bunce commended the depth of UFS’s academic partnerships with the United States and expressed enthusiasm about the university’s future direction. “I’m really excited to hear what you’re looking for in the next few years and how we can continue to work together,” she said.

 

Advancing clinical training and collaboration 

The delegation toured the world-class Clinical Simulation and Skills Unit (CSSU), where Prof Mathys Labuschagne, Head of Clinical Simulation and Skills Unit, School of Biomedical Sciences, and his team showcased how advanced simulation technologies prepare students for clinical practice. “Hands-on practice in a safe, non-threatening environment is one of the best ways to build confidence and skills,” explained Prof Labuschagne. 

The CSSU was developed based on a model from Penn State University following a visit 15 years ago - a collaboration that has continued to thrive. “Collaboration with US universities opens doors for joint teaching, student exchanges, and research partnerships that drive innovation,” Prof Labuschagne added. 

 

Deepening a century of partnership 

Collaboration between the UFS and the U.S universities dates back more than a century. In the 1920s, the University of Michigan established the Lamont-Hussey Observatory on Naval Hill, and Harvard University relocated the Boyden Observatory to Maselspoort. Both observatories, now part of the UFS, symbolise a legacy of shared scientific discovery. 

These historic ties have since evolved into formal agreements with universities across the United States. Between 2020 and 2024, the US was the leading country collaborating with the UFS, producing more than 929 co-authored publications across 648 institutions. Today, partnerships continue to expand through research, academic exchanges, and staff mobility programmes that leave a lasting impact on students and society alike. 

Consul General Bunce highlighted the distinctive nature of these partnerships. “In many countries, academic exchange is driven by government. Here, it grows organically from strong relationships and programmes.”

Prof Lynette Jacobs, interim Director in the Office for International Affairs, emphasised the value of these ties: “Our partnership with the United States shows how a strong and mature relationship can drive diversified internationalisation, advancing our strategic goal of global engagement with real impact. We look forward to welcoming the Consul General on our other two campuses.”   

 

Driving innovation and commercialisation

In her address, Prof Klopper outlined the university’s vision to translate research into real-world solutions and commercial opportunities. “The UFS is learning from many American universities’ innovative models, which leverage multiple income streams and strong industry partnerships,” noted Prof Klopper. Prof Klopper emphasised that diversifying income is not only about sustainability but also about ensuring research has impact. Recent spin-off companies are an example of this vision becoming reality. 

 

Charting the future 

The US delegation expressed strong interest in UFS’s areas of strength, including community engagement, entrepreneurship, and student success initiatives. They also highlighted the potential for US students to study at the UFS, with consular support services in place to assist visiting students in emergencies. 

“It is wonderful to see relationships that grow and change but continue to bring in new partnerships and exchanges,” Consul General Bunce remarked. 

With plans for new mobility schemes, joint research projects, and a shared commitment to innovation, the UFS and its US partners are well-positioned to shape the next chapter in their century-long story of collaboration.  

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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