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04 June 2020 | Story Lacea Loader

It has come to the attention of the University of the Free State (UFS) that false and inaccurate statements have been circulating on Twitter on 4 June 2020, claiming that its students were not equipped or supported to study remotely during the COVID-19 lockdown. The UFS believes that it is important to engage in dialogue to correct any misconceptions and inaccuracies that are at risk of being perpetuated.

Contrary to these reports, the UFS has invested much time and resources in the development and deployment of low-tech online and distance approaches to learning and teaching. Since March 2020, the university has undertaken extensive measures to support its students after classes were suspended and to ensure the continuation of the academic programme.

Statements on Twitter include a number of inaccuracies, which the university wants to correct:

• The Institutional Student Representative Council (ISRC) was not suspended by the Rector and Vice-Chancellor, Prof Francis Petersen. In fact, the university management regularly meets with the ISRC on matters of concern to them. Student representatives also serve on a number of institutional committees – both before and during the national lockdown.
• No deregistration of any students has taken place.
• Since the end of April 2020, structured and managed data was provided to students to obtain access to academic content as well as to the academic platforms for free. However, to access this free data, students need to download the GlobalProtect app – this was communicated numerously and explained to students.  The university’s ICT Services will provide video and technical guides to all students to assist them with downloading the app.
• As of June 2020, all allowances for which students qualify and which are approved by NSFAS, have been paid by the university.
• Although online learning provides a solution to continue with programme delivery, the university is deeply aware of the fact that access may be a barrier – especially during these extraordinary times.  To assist vulnerable students, a total of 3 500 laptops have been procured by the UFS, enabling the university to assist eligible students in accessing the online platforms, obtaining learning material, and engaging with lecturers. The university is in the process of distributing the laptops to students who qualify. The Department of Higher Education, Science and Innovation’s process to provide laptops to students is separate from the 3 500 laptops procured by the UFS.  

The UFS remains committed to supporting its students in response to COVID-19 and is looking forward to working as a community to prepare for the institution’s response to the new challenges of responsibly returning to campus life from June 2020 onward. As staff and students start returning to the institution in a phased approach this month, the UFS will continue to comply with all applicable governmental directives and health guidelines to ensure the safety, health, and well-being of its students and staff.

Released by:
Lacea Loader (Director: Communication and Marketing)
Telephone: +27 51 401 2584 | +27 83 645 2454
Email: news@ufs.ac.za | loaderl@ufs.ac.za

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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