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25 July 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Plant Sciences Congress
At a public seminar, Understanding human evolution through the study of past environments in the Free State, presented by the UFS Department of Plant Sciences, were, from the left, front: Kristen Wroth, Britt Bousman; back: Prof Louis Scott, mentor in the UFS Department of Plant Sciences, and Michael Toffolo.

Florisbad, a thermal spring situated 45 km northwest of Bloemfontein on the edge of a large dry saltpan, is a well-known fossil site that used to be a large lake where giant buffalo, blue wildebeest, and hippos roamed thousands of years ago. Today, this fossil-bearing spring is not only a tourist attraction and a venue for weddings, but also an established quaternary research station that has attracted several palaeo-scientists since the 1930s, following the discovery of a remarkable human cranium and other fauna. 

Studies of past environments 

Three international researchers studying different aspects of archaeology at this and other sites in the Free State, recently presented lectures at the UFS to a multidisciplinary group of academics in plant sciences, geology, geography, and environmental management.

These lectures are part of the ongoing collaboration regarding fossil plant (pollen), fauna, and archaeological studies between the University of the Free State (UFS), the National Museum, and universities abroad.

Florisbad, a key site for understanding the appearance of modern environments as well as modern humans in Southern Africa, is the focus of the investigations of all three visiting scientists, aiming to provide a better understanding of past Free State environments where human evolution has taken place.

Michael Toffolo, a junior research chair from the University of Bordeaux Montaigne in France, focuses on the reconstruction of site-formation processes, palaeo-environments, and ancient human activities based on the study of the micro-morphology of archaeological deposits. He has been working in Southern Africa since 2013. The title of his lecture was: Reconstructing Pleistocene environments in the Free State by looking at the microscopic sedimentary record. 

Fluoride-preserved bones

Florisbad is widely known for the discovery of an archaic modern human skull of c. 260 000 years old. According to Toffolo, the human probably died, and the remains was left at the spring by the hyenas. The bones consequently absorbed fluoride from the spring water, which counteracted decomposition and helped to preserve it. 

Britt Bousman talked about middle and late Pleistocene terraces and archaeology in the Modder River Valley. He has worked in Southern Africa for the past 43 years and started his collaboration with researchers from the UFS and the National Museum in 1985. They have worked together at several sites, investigating palaeo-environments. Bousman teaches Archaeology in the Department of Anthropology at the Texas State University. 

While most scientists study early human records in rock shelters, especially those near the coast where seafood was harvested by prehistoric people, he is one of only a few researchers who studies the evolution of early human behaviour in central South Africa in the context of their activities in the open environment. 

“Rock shelters are good spaces for human behaviour,” says Bousman. He believes, however, that the Modder River area is a better space to study how humans have survived on the land under changing climatic conditions in the long term; for example, how they hunted and slaughtered animals. This can be seen from the many artefacts they left, such as spearheads, scrapers, etc. Interesting animal remains were also found, such as the bones of an extinct giant zebra at the Erfkroon site along the Modder River, with a head measuring 63 cm compared to that of a current zebra, which measures 54 cm. The only complete horn core of an extinct giant wildebeest was also found at the site. 

The first chemists

According to Bousman, technology changed in the Stone Age and included the production of more grinding stones, indicating that humans collected plants and grinded them. Observations of modern plant-collecting activities suggested that not many plant foods needed grinding. Bousman proposes that different plant components may have been grinded for medicinal mixtures, therefore these ancestors may have assumed the role of chemists. 

Kristen Wroth, a postdoctoral researcher in the Geoarchaeology Working Group at the University of Tübingen, Germany, presented a lecture on early human-environment interactions and ancient pyro technology. She uses a suite of micro-archaeological techniques such as phytolith (microscopic plant silica) analysis, micromorphology, and FTIR to understand both human and Neanderthal behaviour and to reconstruct how local environments have changed in space and through time.


News Archive

Champagne and cancer have more in common than you might think
2013-05-08

 

Photo: Supplied
08 May 2013

No, a glass of champagne will not cure cancer....

…But they have more in common than you might think.

Researchers from the Departments of Microbial Biochemical and Food Biotechnology, Physics and the Centre for Microscopy at the University of the Free State in South Africa were recently exploring the properties of yeast cells in wine and food to find out more of how yeast was able to manufacture the gas that caused bread to rise, champagne to fizz and traditional beer to foam. And the discovery they made is a breakthrough that may have enormous implications for the treatment of diseases in humans.

The team discovered that they could slice open cells with argon gas particles, and look inside. They were surprised to find a maze of tiny passages like gas chambers that allowed each cell to ‘breathe.’ It is this tiny set of ‘lungs’ that puts the bubbles in your bubbly and the bounce in your bread.

But it was the technique that the researchers used to open up the cells that caught the attention of the scientists at the Mayo Clinic (Tumor Angiogenesis and Vascular Biology Research Centre) in the US.

Using this technology, they ultimately aim to peer inside cells taken from a cancer patient to see how treatment was progressing. In this way they would be able to assist the Mayo team to target treatments more effectively, reduce dosages in order to make treatment gentler on the patient, and have an accurate view of how the cancer was being eliminated.

“Yes, we are working with the Mayo Clinic,” said Profes Lodewyk Kock from the Microbial, Biochemical and Food Biotechnology Department at the UFS.

“This technique we developed has enormous potential for cell research, whether it is for cancer treatment or any other investigation into the working of cells. Through nanotechnology, and our own invention called Auger-architectomics, we are able to see where no-one has been able to see before.”

The team of Prof Kock including Dr Chantel Swart, Kumisho Dithebe, Prof Hendrik Swart (Physics, UFS) and Prof Pieter van Wyk (Centre for Microscopy, UFS) unlocked the ‘missing link’ that explains the existence of bubbles inside yeasts, and incidentally have created a possible technique for tracking drug and chemotherapy treatment in human cells.

Their work has been published recently in FEMS Yeast Research, the leading international journal on yeast research. In addition, their discovery has been selected for display on the cover page of all 2013 issues of this journal.

One can most certainly raise a glass of champagne to celebrate that!

There are links for video lectures on the technique used and findings on the Internet at:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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