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29 July 2019 | Story Leonie Bolleurs
Dr Martin Clark
Dr Martin Clark, the founder of the MAGIC (Multi-purpose Aerial Geological Image Classification) initiative. MAGIC can obtain geological and structural information that is critical for making informed decisions in exploration and mineral extraction processes.

Mining has historically been described as a boom-and-bust industry, where fluctuations in mineral prices could result in extreme success or bankruptcy. Successful mining companies closely monitor assets/expenditures, risks, and other parameters associated with their business to best ensure their longevity. In most mineral industries, there are a few competitors that dominate the delivery of a mineral resource. As a result, technological development, along with other factors, are critical to ensure that these companies’ business remains viable and protected.

This is according to post-doctoral fellow in the Department of Geology, Dr Martin Clark.

Drone technology: better, faster, safer

He says technological development in mining generally translates to how a company can extract a resource from the ground better, faster, and safer. 

Dr Clark believes the rapid development of drone technology represents a shift in the toolbox that mining companies can employ.

“Drones can collect a great deal of data randomly over vast or small areas within hours, historically accomplished by mapping campaigns which can last months to years. Drones can also collect data in areas which are difficult and dangerous for humans to get to. These include cliff faces or rock walls that are difficult and dangerous to get close to, as well as stretches of land where dense vegetation, inaccessible terrain, and even atmospheric dangers become factors which reduce or modify the scope of exploration work,” he said. 

Expanding application of drones

Dr Clark’s work specifically focuses on expanding the applications for which drones are used. “I assess what and how good the imaging capabilities of drones are, use the imagery to generate 3-D models to drive scientific observation, and yield results which can help companies to extract resources. This initiative is called MAGIC (Multi-purpose Aerial Geological Image Classification),” he said. 



“MAGIC aims to collect geological and structural information that is critical for making informed decisions in exploration and mineral extraction processes,” he added.

Dr Clark is not only the founder of MAGIC; he also drives multiple aspects of the initiative including education, research, and business development. 

In 2013, when he was busy with his doctorate, there was already a spark of interest in using drones to address geological questions. At that time, Dr Clark was working with remotely sensed high-resolution LiDAR imagery to better understand geological structures at the Sudbury Mining Camp in Canada. The interest became a reality in 2018, when he applied this initiative during his post-doctoral fellowship at the UFS.

Now and the future

“At present, there are no direct mining projects underway, but projects are expected to begin in 2020. Drone operation and image-analysis techniques are currently being refined for industry,” he said. 

Besides his work with drones, Dr Clark also work in the fields of structural geology, remote sensing, and geospatial data analysis.  

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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