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18 June 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Christine Engelbrecht from the Agricultural Research Council
Dr Christine Engelbrecht from the Agricultural Research Council presented the keynote lecture on climate dynamics, predicting that El Niños will double in frequency towards the end of the century.

The world will need nearly double the current food supply by 2050 to feed an ever-increasing world population. This is a mammoth, almost impossible task.

Building on knowledge

According to UFS Rector and Vice-Chancellor, Prof Francis Petersen, if we approach challenges such as these with scientific level-headedness, systematically build on knowledge and experience gained, and draw on similar inputs from other specialist fields, the seemingly impossible becomes possible.

“To what extent do we integrate our knowledge across sectors – within the university and outside the university; on the continent as well as globally?” he asked the 300-plus delegates, which included animal scientists, students, and various other role players in the livestock sector, at the 51st South African Society of Animal Science (SASAS) congress on the Bloemfontein Campus of the University of the Free State (UFS). 

Willingness to adapt to new strategies


The theme of this year’s congress was: Managing the ecological footprint of livestock through efficient production. The congress provided a platform for discussions on the impact of livestock production – bringing in elements of critical thinking, as well as the willingness to adopt new strategies. 

During the congress, workshops on topics such as silage, predation management, intensive sheep production, prickly-pear utilisation, and animal welfare provided delegates with the opportunity to discuss challenges faced by the South African livestock producer.

Dr Christine Engelbrecht (Meteorology) from the Agricultural Research Council presented the first keynote address, focusing on climate dynamics. 

“We have high-impact weather systems across Southern Africa. It is projected that strong El Niños are to double in frequency towards the end of the 21st century,” said Dr Engelbrecht. 

She further predicted temperature increases of between 4 and 7 degrees Celsius in the interior before the end of the century. Over the Free State, Northern Cape, and North-West Province, we can expect shorter frost seasons, significant increases in maximum temperatures for both summer and winter, as well as more frequent El Niño-induced droughts. 

Ecological footprint of food

Improved production outputs need to be achieved by using less land, water, and available energy, while ensuring that the degradation and pollution of natural resources are limited. A scientific approach would be a viable option to improve the efficiency of livestock production.

SASAS President, Prof Este van Marle-Köster from the University of Pretoria, pointed out that all food had an ecological impact.

Dr Frikkie Maré, Head of the Department of Agricultural Economics at the UFS, presented a keynote lecture on managing the footprint of beef through efficient production. Comparing the water footprint of different cattle breeds, his question was what could be done to reduce this. 

Animal welfare was introduced to the congress for the first time. Prof Cathy Dwyer from Scotland’s Rural College presented a session on, ‘Can animal welfare contribute to improved production efficiency?’

The oldest conception of animal welfare is the five freedoms adapted to the five welfare needs of animals, namely a suitable environment, a suitable diet, exhibiting normal behaviour patterns, being with or being apart from other animals, and protection from pain, injury, suffering, and disease. Studies demonstrate that animal welfare can be an important and effective part of production efficiency, and that animal welfare should be seen as an integral component of improving the sustainability of livestock. 

Prof HO de Waal from the Predation Management Centre at the UFS presented a session on the impact of predation on livestock production, with the tile: The need for coordinated predation management in South Africa – quo vadis? He said: “The current approach to predation management is fragmented and uncoordinated. Solutions for the management of human-wildlife conflict require a South African institutional memory. Most of the information on predation and the hunting of predators is held by specialist predator hunters and farmers. In a system of coordinated predation management, farmers and government are equal partners, each with specific responsibilities.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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